Enantioselective synthesis of (R)-deoxydysibetaine and (-)-4-epi-dysibetaine

Tetrahedron Letters

Volumn 48, Issue 27, 2007, Pages 4691-4694

  Katoh, Miho ^a   Hisa, Chihiro ^a   Honda, Toshio ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

, Disubstituted amino acid; ( ) 4 epi Dysibetaine; (R) Deoxydydibetaine; Reductive carbon nitrogen bond cleavage; Samarium iodide

Indexed keywords

4 EPI DYSIBETAINE; AMINO ACID DERIVATIVE; CARBON; DEOXYDYSIBATAINE; NITROGEN; PROLINE DERIVATIVE; SAMARIUM; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; DRUG SYNTHESIS; ENANTIOSELECTIVITY;

EID: 34249904687     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.05.007     Document Type: Article

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19. 1H NMR analysis.
20. In this reaction, all the starting materials were converted to the desired compound on TLC monitoring, however, the yield of γ-lactam 13 might be decreased during deprotection of Boc group with TFA and subsequent recyclization sequences.
21. ++1): 229.1560. Found 229.1552.
22. +): 344.1947. Found 344.1946.