Colorimetric microarray detection system for ghrelin using aptamer-technology

Analytical Letters

Volumn 40, Issue 7, 2007, Pages 1386-1399

  Mascini, Marcello ^a,b   Guilbault, George G ^a   Lebrun, Stewart J ^c   Compagnone, Dario ^b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY OF TERAMO   (Italy)

^c Miragene Inc   (United States)

Author keywords

Colorimetric microarray; ELONA; Ghrelin; Spiegelmer

Indexed keywords

EID: 34249864490     PISSN: 00032719     EISSN: 1532236X     Source Type: Journal    
DOI: 10.1080/00032710701327062     Document Type: Article

References (23)

1. Christensen, C.B.V. 2002. Arrays in biological and chemical analysis. Talanta, 56: 289-299.
2. Churchill, G.A. 2002. Fundamentals of experimental design for cDNA microarrays. Nature Genetics, 32: 490-495.
3. De Ambrogi, M., Volpe, S., and Tamanini, C. 2003. Ghrelin: central and peripheral effects of a novel peptidyl hormone. Medical Science Monitoring, 9: 217-224.
4. Ekins, R.P. 1989. Multi-analyte immunoassay. Biomed Anal., 7: 155-168.
5. Helmling, S., Maasch, C., Eulberg, D., Buchner, K., Schroder, W., Lange, C., Vonhoff, S., Wlotzka, B., Tschop, M.H., Rosewicz, S., and Klussmann, S. 2004. Inhibition of ghrelin action in vitro and in vivo by an RNA-Spiegelmer. Proc. Natl Acad. Sci. USA, 101: 13174-13179.
6. Jarosch, F., Buchner, K., and Klussmann, S. 2006. In vitro selection using a dual RNA library that allows primerless selection. Nucleic Acids Res., 34: e86.
7. Kojima, M., Hosoda, H., Date, Y., Nakazato, M., Matsuo, H., and Kangawa, K. 1999. Ghrelin is a growth hormone releasing acylated peptide from stomach. Nature, 402: 656-660.
8. Lebrun, S.J. 2004. Development of a low-cost colorimetric protein array system to measure human autoimmune disease. Preclinica, 2 (4): 267-174.
9. Lebrun, S.J., Petchpud, W.N., Hui, A., and McLaughlin, C.S. 2005. Development of a sensitive, colorometric microarray assay for allergen-responsive human IgE. J. Immunol. Methods, 300: 24-31.
10. Lebrun, S.J. and Van Renterghem, B. 2006. Performance characteristics of colorimetric protein microarrays compared to ELISA. Assay Drug Dev Technol., 4: 197-202.
11. Leva, S., Lichte, A., Burmeister, J., Muhn, P., Jahnke, B., Fesser, D., Erfurth, J., Burgstaller, P., and Klussmann, S. 2002. GnRH-binding RNA and DNA Spiegelmers-a novel approach towards GnRH antagonism. Chem. Biol., 9: 351-359.
12. Liang, R.Q., Tan, C.Y., and Ruan, K.C. 2004. Colorimetric detection of protein microarrays based on nanogold probe coupled with silver enhancement. J. Immunol. Methods, 285: 157-163.
13. Lopez, M.F. and Pluskal, M.G. 2003. Protein micro- and macro-arrays: digitizing the proteome. J. Chromatogr. B, 787: 19-27.
14. Luzi, E., Minunni, M., Tombelli, S., and Mascini, M. 2003. New trends in affinity sensing: aptamers for ligand binding. Trends Anal. Chem., 22: 810-818.
15. MacBeath, G. and Schreiber, S.L. 2000. Printing proteins as microarrays for high-throughput function determination. Science, 289: 1760-1763.
16. Mascini, M., Papamichael, K., Mevola, I., Pravda, M., and Guilbault, G.G. 2007. A mini-review: ghrelin detection using spiegelmer-capture molecules. Anal. Lett., 40: 403-430.
17. Purschke, G., Radtke, F., Kleinjung, F., and Klussmann, S. 2003. A DNA Spiegelmer to staphylococcal enterotoxin B. Nucleic Acids Res., 31: 3027-3032.
18. Robinson, W.H., DiGennaro, C., Hueber, W., Haab, B.B., Kamachi, M., Dean, E.J., Fournel, S., Fong, D., Genovese, M.C., de Vegvar, H.E., Skriner, K., Hirschberg, D.L., Morris, R.I., Muller, S., Pruijn, G.J., van Venrooij, W.J., Smolen, J.S., Brown, P.O., Steinman, L., and Utz, P.J. 2002. Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat. Med., 8: 295-301.
19. Suslick, K.S., Rakow, N.A., and Sen, A. 2004. Colorimetric sensor arrays for molecular recognition. Tetrahedron, 60: 11133-11138.
20. Taussig, M.J. and Landegren, U. 2003. Progress in antibody arrays. Drug discovery Today: Targets, 2: 169-176.
21. Tombelli, S., Minunni, A., and Mascini, M. 2005. Analytical applications of aptamers. Biosensors & Bioelectronics, 20: 2424-2434.
22. Wlotzka, B., Leva, S., Eschgfaller, B., Burmeister, J., Kleinjung, F., Kaduk, C., Muhn, P., Hess-Stumpp, H., and Klussmann, S. 2002. In vivo properties of an anti-GnRH Spiegelmer: an example of an oligonucleotide-based therapeutic substance class. Proc. Nat. Acad. Sci., 99: 8898-8902.
23. Young, R.A. 2000. Biomedical discovery with DNA arrays. Cell, 102: 9-15.