Sorting out the clinical consequences of ischemic lesions in brain aging: A clinicopathological approach

Journal of the Neurological Sciences

Volumn 257, Issue 1-2, 2007, Pages 17-22

  Gold, Gabriel ^a   Kovari, Enikö ^a   Hof, Patrick R ^c   Bouras, Constantin ^a,c   Giannakopoulos, Panteleimon ^a,b  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b University of Lausanne Medical Center   (Switzerland)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Aging; Brain ischemia; Cognition; Lacunes; Vascular dementia

Indexed keywords

AGING; ALZHEIMER DISEASE; ARTICLE; AUTOPSY; BASAL GANGLION; BRAIN INFARCTION; BRAIN ISCHEMIA; BRAIN MAPPING; CLINICAL FEATURE; COGNITIVE DEFECT; DEMYELINATION; DIFFUSE LEWY BODY DISEASE; DISEASE CLASSIFICATION; FRONTAL LOBE; GLIOSIS; HUMAN; IMAGE ANALYSIS; INTELLECTUAL IMPAIRMENT; INTELLIGENCE; NEUROIMAGING; NEUROPATHOLOGY; PARIETAL LOBE; PRIORITY JOURNAL; RISK FACTOR; TEMPORAL LOBE; THALAMIC LACUNE; THALAMUS; WHITE MATTER;

AGED; AGING; BRAIN; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBRAL ARTERIES; COGNITION DISORDERS; DEMENTIA, VASCULAR; HUMANS; MICROCIRCULATION; NERVE FIBERS, MYELINATED;

EID: 34249830165     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2007.01.020     Document Type: Article

References (44)

1. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS). Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Lancet 357 (2001) 169-175
2. Alzheimer A. Die arteriosklertische Atrophie des Gehirns. Allg Z Psychiatr 51 (1895) 1809-1812
3. Bowler J.V., Steenhuis R., and Hachinski V. Conceptual background to vascular cognitive impairment. Alzheimer Dis Assoc Disord 13 Suppl 3 (1999) S30-S37
4. Braak H., and Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol 82 (1991) 239-259
5. Bracco L., Campani D., Baratti E., Lippi A., Inzitari D., Pracucci G., et al. Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: a longitudinal study. J Neurol Sci 120 (1993) 131-136
6. Bracco L., Piccini C., Moretti M., Mascalchi M., Sforza A., Nacmias B., et al. Alzheimer's disease: role of size and location of white matter changes in determining cognitive deficits. Dement Geriatr Cogn Disord 20 (2005) 358-366
7. Desmond D.W., Moroney J.T., Sano M., and Stern Y. Incidence of dementia after ischemic stroke: results of a longitudinal study. Stroke 33 (2002) 2254-2260
8. Erkinjuntti T. Subcortical vascular dementia. Cerebrovasc Dis 13 (2002) 58-60
9. Esiri M.M. Which vascular lesions are of importance in vascular dementia?. Ann N Y Acad Sci 903 (2000) 239-243
10. Garde E., Mortensen E.L., Krabbe K., Rostrup E., and Larsson H.B. Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study. Lancet 356 (2000) 628-634
11. Giannakopoulos P., Hermann F.R., Bouras C., Kovari E., Perl D.P., Morrison J.H., et al. Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease. Neurology 60 (2003) 1495-1500
12. Gold G., Bouras C., Canuto A., Bergallo M.F., Herrmann F.R., Hof P.R., et al. Clinicopathological validation study of four sets of clinical criteria for vascular dementia. Am J Psychiatry 159 (2002) 82-87
13. Gold G., Bouras C., Kovari E., Canuto A., Glaria B.G., Malky A., et al. Clinical validity of Braak neuropathological staging in the oldest-old. Acta Neuropathol (Berl) 99 (2000) 579-582 [discussion 583-574]
14. Gold G., Bouras C., Michel J.-P., Hof P.R., and Giannakopoulos P. Vascular Dementia. In: Hof P.R., and Mobbs C.V. (Eds). Functional neurobiology of aging (2001), Academic Press, San Diego 131-143
15. Gold G., Giannakopoulos P., Montes-Paixao Junior C., Herrmann F.R., Mulligan R., Michel J.P., et al. Sensitivity and specificity of newly proposed clinical criteria for possible vascular dementia. Neurology 49 (1997) 690-694
16. Gold G., Kovari E., Corte G., Herrmann F.R., Canuto A., Bussiere T., et al. Clinical validity of A beta-protein deposition staging in brain aging and Alzheimer disease. J Neuropathol Exp Neurol 60 (2001) 946-952
17. Gold G., Kovari E., Herrmann F.R., Canuto A., Hof P.R., Michel J.P., et al. Cognitive consequences of thalamic, basal ganglia, and deep white matter lacunes in brain aging and dementia. Stroke 36 (2005) 1184-1188
18. Hachinski V. Vascular dementia: a radical redefinition. Dementia 5 (1994) 130-132
19. Hachinski V.D., Lassen N.A., and Marshall J. Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet 2 (1974) 207-210
20. Hughes C.P., Berg L., Danziger W.L., Coben L.A., and Martin R.L. A new clinical scale for the staging of dementia. Brit J Psychiat 140 (1982) 566-572
21. Jellinger K.A., and Attems J. Incidence of cerebrovascular lesions in Alzheimer's disease: a postmortem study. Acta Neuropathol (Berl) 105 (2003) 14-17
22. Kovari E., Gold G., Herrmann F.R., Canuto A., Hof P.R., Michel J.P., et al. Cortical microinfarcts and demyelination significantly affect cognition in brain aging. Stroke 35 (2004) 410-414
23. Lee J.H., Olichney J.M., Hansen L.A., Hofstetter C.R., and Thal L.J. Small concomitant vascular lesions do not influence rates of cognitive decline in patients with alzheimer disease [in process citation]. Arch Neurol 57 (2000) 1474-1479
24. Loeb C. The history of vascular dementia. J Hist Neurosci 4 (1995) 121-126
25. Longstreth Jr. W.T., Manolio T.A., Arnold A., Burke G.L., Bryan N., Jungreis C.A., et al. Clinical correlates of white matter findings on cranial magnetic resonance imaging of 3301 elderly people. The Cardiovascular Health Study. Stroke 27 (1996) 1274-1282
26. Mackowiak-Cordoliani M.A., Bombois S., Memin A., Henon H., and Pasquier F. Poststroke dementia in the elderly. Drugs Aging 22 (2005) 483-493
27. Morris J.C. The Clinical Dementia Rating (CDR): current version and scoring rules. Neurology 43 (1993) 2412-2414
28. O'Brien J.T., Erkinjuntti T., Reisberg B., Roman G., Sawada T., Pantoni L., et al. Vascular cognitive impairment. Lancet Neurol 2 (2003) 89-98
29. Roman G.C., Erkinjuntti T., Wallin A., Pantoni L., and Chui H.C. Subcortical ischaemic vascular dementia. Lancet Neurol 1 (2002) 426-436
30. Roman G.C., and Royall D.R. Executive control function: a rational basis for the diagnosis of vascular dementia. Alzheimer Dis Assoc Disord 13 Suppl 3 (1999) S69-S80
31. Schmidt R., Schmidt H., Kapeller P., Lechner A., and Fazekas F. Evolution of white matter lesions. Cerebrovasc Dis 13 (2002) 16-20
32. Schmidtke K., and Hull M. Cerebral small vessel disease: how does it progress?. J Neurol Sci 229-230 (2005) 13-20
33. Snowdon D.A., Greiner L.H., Mortimer J.A., Riley K.P., Greiner P.A., and Markesbery W.R. Brain infarction and the clinical expression of Alzheimer disease. The Nun Study. Jama 277 (1997) 813-817
34. Tang W.K., Chan S.S., Chiu H.F., Ungvari G.S., Wong K.S., Kwok T.C., et al. Frequency and determinants of poststroke dementia in Chinese. Stroke 35 (2004) 930-935
35. Tatemichi T.K., Paik M., Bagiella E., Desmond D.W., Stern Y., Sano M., et al. Risk of dementia after stroke in a hospitalized cohort: results of a longitudinal study. Neurology 44 (1994) 1885-1891
36. Thal D.R., Rub U., Schultz C., Sassin I., Ghebremedhin E., Del Tredici K., et al. Sequence of Abeta-protein deposition in the human medial temporal lobe. J Neuropathol Exp Neurol 59 (2000) 733-748
37. Tomlinson B.E., Blessed G., and Roth M. Observations on the brains of demented old people. J Neurol Sci 11 (1970) 205-242
38. Tomlinson B.E., Blessed G., and Roth M. Observations on the brains of non-demented old people. J Neurol Sci 7 (1968) 331-356
39. Udaka F., Sawada H., and Kameyama M. White matter lesions and dementia: MRI-pathological correlation. Ann N Y Acad Sci 977 (2002) 411-415
40. van der Flier W.M., van Straaten E.C., Barkhof F., Verdelho A., Madureira S., Pantoni L., et al. Small vessel disease and general cognitive function in nondisabled elderly: the LADIS study. Stroke 36 (2005) 2116-2120
41. Vermeer S.E., Prins N.D., den Heijer T., Hofman A., Koudstaal P.J., and Breteler M.M. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 348 (2003) 1215-1222
42. Wallin A., and Blennow K. Clinical subgroups of the Alzheimer syndrome. Acta Neurol Scand 165 (1996) 51-57 [Suppl]
43. Wen H.M., Mok V.C., Fan Y.H., Lam W.W., Tang W.K., Wong A., et al. Effect of white matter changes on cognitive impairment in patients with lacunar infarcts. Stroke 35 (2004) 1826-1830
44. Ylikoski A., Erkinjuntti T., Raininko R., Sarna S., Sulkava R., and Tilvis R. White matter hyperintensities on MRI in the neurologically nondiseased elderly. Analysis of cohorts of consecutive subjects aged 55 to 85 years living at home. Stroke 26 (1995) 1171-1177