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Volumn 115, Issue 6, 2007, Pages 687-700

Latent transforming growth factor binding protein 4 (LTBP-4) is downregulated in human mammary adenocarcinomas in vitro and in vivo

Author keywords

Carcinogenesis tumour suppressor gene; Human mammary tumour; LTBP 4; TGF

Indexed keywords

BINDING PROTEIN; LATENT TRANSFORMING GROWTH FACTOR BINDING PROTEIN 4; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

EID: 34249827577     PISSN: 09034641     EISSN: 16000463     Source Type: Journal    
DOI: 10.1111/j.1600-0463.2007.apm_453.x     Document Type: Article
Times cited : (18)

References (38)
  • 1
    • 0029813731 scopus 로고    scopus 로고
    • Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils
    • Taipale J, Saharinen J, Hedman K, Keski-Oja J. Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils. J Histochem Cytochem 1996 44 : 875 89.
    • (1996) J Histochem Cytochem , vol.44 , pp. 875-89
    • Taipale, J.1    Saharinen, J.2    Hedman, K.3    Keski-Oja, J.4
  • 2
    • 0028180315 scopus 로고
    • The TGF-beta superfamily: New members, new receptors, and new genetic tests of function in different organisms
    • Kingsley DM. The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 1994 8 : 133 46.
    • (1994) Genes Dev , vol.8 , pp. 133-46
    • Kingsley, D.M.1
  • 3
    • 0023786978 scopus 로고
    • Comparison of the biological actions of TGF beta-1 and TGF beta-2: Differential activity in endothelial cells
    • Jennings JC, Mohan S, Linkhart TA, Widstrom R, Baylink DJ. Comparison of the biological actions of TGF beta-1 and TGF beta-2: differential activity in endothelial cells. J Cell Physiol 1988 137 : 167 72.
    • (1988) J Cell Physiol , vol.137 , pp. 167-72
    • Jennings, J.C.1    Mohan, S.2    Linkhart, T.A.3    Widstrom, R.4    Baylink, D.J.5
  • 4
    • 0026701960 scopus 로고
    • Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form
    • Miyazono K, Thyberg J, Heldin CH. Retention of the transforming growth factor-beta 1 precursor in the Golgi complex in a latent endoglycosidase H-sensitive form. J Biol Chem 1992 267 : 5668 75.
    • (1992) J Biol Chem , vol.267 , pp. 5668-75
    • Miyazono, K.1    Thyberg, J.2    Heldin, C.H.3
  • 5
    • 0025244163 scopus 로고
    • Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues
    • Tsuji T, Okada F, Yamaguchi K, Nakamura T. Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues. Proc Natl Acad Sci U S A 1990 87 : 8835 9.
    • (1990) Proc Natl Acad Sci U S a , vol.87 , pp. 8835-9
    • Tsuji, T.1    Okada, F.2    Yamaguchi, K.3    Nakamura, T.4
  • 6
    • 0028582165 scopus 로고
    • Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein
    • Moren A, Olofsson A, Stenman G, Sahlin P, Kanzaki T, Claesson-Welsh L, et al. Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein. J Biol Chem 1994 269 : 32469 78.
    • (1994) J Biol Chem , vol.269 , pp. 32469-78
    • Moren, A.1    Olofsson, A.2    Stenman, G.3    Sahlin, P.4    Kanzaki, T.5    Claesson-Welsh, L.6
  • 7
    • 0028900639 scopus 로고
    • Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3)
    • Yin W, Smiley E, Germiller J, Mecham RP, Florer JB, Wenstrup RJ, et al. Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3). J Biol Chem 1995 270 : 10147 60.
    • (1995) J Biol Chem , vol.270 , pp. 10147-60
    • Yin, W.1    Smiley, E.2    Germiller, J.3    Mecham, R.P.4    Florer, J.B.5    Wenstrup, R.J.6
  • 8
    • 0028857166 scopus 로고
    • Bovine latent transforming growth factor beta 1-binding protein 2: Molecular cloning, identification of tissue isoforms, and immunolocalization to elastin-associated microfibrils
    • Gibson MA, Hatzinikolas G, Davis EC, Baker E, Sutherland GR, Mecham RP. Bovine latent transforming growth factor beta 1-binding protein 2: molecular cloning, identification of tissue isoforms, and immunolocalization to elastin-associated microfibrils. Mol Cell Biol 1995 15 : 6932 42.
    • (1995) Mol Cell Biol , vol.15 , pp. 6932-42
    • Gibson, M.A.1    Hatzinikolas, G.2    Davis, E.C.3    Baker, E.4    Sutherland, G.R.5    Mecham, R.P.6
  • 9
    • 0027976521 scopus 로고
    • Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein
    • Taipale J, Miyazono K, Heldin CH, Keski-Oja J. Latent transforming growth factor-beta 1 associates to fibroblast extracellular matrix via latent TGF-beta binding protein. J Cell Biol 1994 124 : 171 81.
    • (1994) J Cell Biol , vol.124 , pp. 171-81
    • Taipale, J.1    Miyazono, K.2    Heldin, C.H.3    Keski-Oja, J.4
  • 10
    • 0032493659 scopus 로고    scopus 로고
    • Recombinant latent transforming growth factor beta-binding protein 2 assembles to fibroblast extracellular matrix and is susceptible to proteolytic processing and release
    • Hyytiainen M, Taipale J, Heldin CH, Keski-Oja J. Recombinant latent transforming growth factor beta-binding protein 2 assembles to fibroblast extracellular matrix and is susceptible to proteolytic processing and release. J Biol Chem 1998 273 : 20669 76.
    • (1998) J Biol Chem , vol.273 , pp. 20669-76
    • Hyytiainen, M.1    Taipale, J.2    Heldin, C.H.3    Keski-Oja, J.4
  • 11
    • 0027199916 scopus 로고
    • Increased mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor beta 1 levels during monoterpene-induced regression of mammary tumors
    • Jirtle RL, Haag JD, Ariazi EA, Gould MN. Increased mannose 6-phosphate/insulin-like growth factor II receptor and transforming growth factor beta 1 levels during monoterpene-induced regression of mammary tumors. Cancer Res 1993 53 : 3849 52.
    • (1993) Cancer Res , vol.53 , pp. 3849-52
    • Jirtle, R.L.1    Haag, J.D.2    Ariazi, E.A.3    Gould, M.N.4
  • 12
    • 20244383746 scopus 로고    scopus 로고
    • Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk
    • Kaklamani VG, Baddi L, Liu J, Rosman D, Phukan S, Bradley C, et al. Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk. Cancer Res 2005 65 : 3454 61.
    • (2005) Cancer Res , vol.65 , pp. 3454-61
    • Kaklamani, V.G.1    Baddi, L.2    Liu, J.3    Rosman, D.4    Phukan, S.5    Bradley, C.6
  • 13
    • 2942571940 scopus 로고    scopus 로고
    • Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer?
    • Elkak AE, Newbold RF, Thomas V, Mokbel K. Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer? Cancer Cell Int 2003 3 : 9.
    • (2003) Cancer Cell Int , vol.3 , pp. 9
    • Elkak, A.E.1    Newbold, R.F.2    Thomas, V.3    Mokbel, K.4
  • 14
    • 0038756352 scopus 로고    scopus 로고
    • Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer
    • Jeruss JS, Sturgis CD, Rademaker AW, Woodruff TK. Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer. Cancer Res 2003 63 : 3783 90.
    • (2003) Cancer Res , vol.63 , pp. 3783-90
    • Jeruss, J.S.1    Sturgis, C.D.2    Rademaker, A.W.3    Woodruff, T.K.4
  • 16
    • 21844480415 scopus 로고    scopus 로고
    • TGF-beta1 could be a missing link in the interplay between ER and HER-2 in breast cancer
    • Todorovic-Rakovic N. TGF-beta1 could be a missing link in the interplay between ER and HER-2 in breast cancer. Med Hypotheses 2005 65 : 546 51.
    • (2005) Med Hypotheses , vol.65 , pp. 546-51
    • Todorovic-Rakovic, N.1
  • 17
    • 22944453695 scopus 로고    scopus 로고
    • Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor alpha positive breast cancer cells
    • Li Q, Wu L, Oelschlager DK, Wan M, Stockard CR, Grizzle WE, et al. Smad4 inhibits tumor growth by inducing apoptosis in estrogen receptor alpha positive breast cancer cells. J Biol Chem 2005 280 : 27022 8.
    • (2005) J Biol Chem , vol.280 , pp. 27022-8
    • Li, Q.1    Wu, L.2    Oelschlager, D.K.3    Wan, M.4    Stockard, C.R.5    Grizzle, W.E.6
  • 18
    • 10344249892 scopus 로고    scopus 로고
    • Transforming growth factor (TGF)-beta in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells
    • Kim ES, Kim MS, Moon A. Transforming growth factor (TGF)-beta in conjunction with H-ras activation promotes malignant progression of MCF10A breast epithelial cells. Cytokine 2005 29 : 84 91.
    • (2005) Cytokine , vol.29 , pp. 84-91
    • Kim, E.S.1    Kim, M.S.2    Moon, A.3
  • 19
    • 0027237465 scopus 로고
    • Lack of the latent transforming growth factor beta binding protein in malignant, but not benign prostatic tissue
    • Eklov S, Funa K, Nordgren H, Olofsson A, Kanzaki T, Miyazono K, et al. Lack of the latent transforming growth factor beta binding protein in malignant, but not benign prostatic tissue. Cancer Res 1993 53 : 3193 7.
    • (1993) Cancer Res , vol.53 , pp. 3193-7
    • Eklov, S.1    Funa, K.2    Nordgren, H.3    Olofsson, A.4    Kanzaki, T.5    Miyazono, K.6
  • 20
    • 0025364777 scopus 로고
    • TGF-beta 1 binding protein: A component of the large latent complex of TGF-beta 1 with multiple repeat sequences
    • Kanzaki T, Olofsson A, Moren A, Wernstedt C, Hellman U, Miyazono K, et al. TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences. Cell 1990 61 : 1051 61.
    • (1990) Cell , vol.61 , pp. 1051-61
    • Kanzaki, T.1    Olofsson, A.2    Moren, A.3    Wernstedt, C.4    Hellman, U.5    Miyazono, K.6
  • 21
    • 0028302076 scopus 로고
    • Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein
    • Dallas SL, Park-Snyder S, Miyazono K, Twardzik D, Mundy GR, Bonewald LF. Characterization and autoregulation of latent transforming growth factor beta (TGF beta) complexes in osteoblast-like cell lines. Production of a latent complex lacking the latent TGF beta-binding protein. J Biol Chem 1994 269 : 6815 21.
    • (1994) J Biol Chem , vol.269 , pp. 6815-21
    • Dallas, S.L.1    Park-Snyder, S.2    Miyazono, K.3    Twardzik, D.4    Mundy, G.R.5    Bonewald, L.F.6
  • 22
    • 0032729963 scopus 로고    scopus 로고
    • Independent promoters regulate the expression of two amino terminally distinct forms of latent transforming growth factor-beta binding protein-1 (LTBP-1) in a cell type-specific manner
    • Koski C, Saharinen J, Keski-Oja J. Independent promoters regulate the expression of two amino terminally distinct forms of latent transforming growth factor-beta binding protein-1 (LTBP-1) in a cell type-specific manner. J Biol Chem 1999 274 : 32619 30.
    • (1999) J Biol Chem , vol.274 , pp. 32619-30
    • Koski, C.1    Saharinen, J.2    Keski-Oja, J.3
  • 23
    • 0034672359 scopus 로고    scopus 로고
    • The latent transforming growth factor beta binding protein (LTBP) family
    • Oklu R, Hesketh R. The latent transforming growth factor beta binding protein (LTBP) family. Biochem J 2000 352 (Pt 3 601 10.
    • (2000) Biochem J , vol.352 , Issue.3 , pp. 601-10
    • Oklu, R.1    Hesketh, R.2
  • 24
    • 0034816067 scopus 로고    scopus 로고
    • Evidence for the decreased expression of the latent TGF-beta binding protein and its splice form in human liver tumours
    • Roth-Eichhorn S, Heitmann B, Flemming P, Kubicka S, Trautwein C. Evidence for the decreased expression of the latent TGF-beta binding protein and its splice form in human liver tumours. Scand J Gastroenterol 2001 36 : 1204 10.
    • (2001) Scand J Gastroenterol , vol.36 , pp. 1204-10
    • Roth-Eichhorn, S.1    Heitmann, B.2    Flemming, P.3    Kubicka, S.4    Trautwein, C.5
  • 25
    • 0029117933 scopus 로고
    • Expression and prognostic significance of TGF-beta isotypes, latent TGF-beta 1 binding protein, TGF-beta type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms
    • Henriksen R, Gobl A, Wilander E, Oberg K, Miyazono K, Funa K. Expression and prognostic significance of TGF-beta isotypes, latent TGF-beta 1 binding protein, TGF-beta type I and type II receptors, and endoglin in normal ovary and ovarian neoplasms. Lab Invest 1995 73 : 213 20.
    • (1995) Lab Invest , vol.73 , pp. 213-20
    • Henriksen, R.1    Gobl, A.2    Wilander, E.3    Oberg, K.4    Miyazono, K.5    Funa, K.6
  • 26
    • 0028567762 scopus 로고
    • Expression of transforming growth factors beta 1, beta 2, beta 3 in neuroendocrine tumors of the digestive system
    • Chaudhry A, Oberg K, Gobl A, Heldin CH, Funa K. Expression of transforming growth factors beta 1, beta 2, beta 3 in neuroendocrine tumors of the digestive system. Anticancer Res 1994 14 : 2085 91.
    • (1994) Anticancer Res , vol.14 , pp. 2085-91
    • Chaudhry, A.1    Oberg, K.2    Gobl, A.3    Heldin, C.H.4    Funa, K.5
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001 25 : 402 8.
    • (2001) Methods , vol.25 , pp. 402-8
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 0003747224 scopus 로고
    • Verlag Urban & Schwarzenberg: München, Wien, Baltimore
    • Romeis B. Mikroskopische Technik. 17 ed : Verlag Urban & Schwarzenberg : München, Wien, Baltimore, 1989.
    • (1989) Mikroskopische Technik. 17 Ed
    • Romeis, B.1
  • 29
    • 0033775615 scopus 로고    scopus 로고
    • Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
    • Bustin SA. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol 2000 25 : 169 93.
    • (2000) J Mol Endocrinol , vol.25 , pp. 169-93
    • Bustin, S.A.1
  • 30
    • 0025765844 scopus 로고
    • A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1
    • Miyazono K, Olofsson A, Colosetti P, Heldin CH. A role of the latent TGF-beta 1-binding protein in the assembly and secretion of TGF-beta 1. Embo J 1991 10 : 1091 101.
    • (1991) Embo J , vol.10 , pp. 1091-101
    • Miyazono, K.1    Olofsson, A.2    Colosetti, P.3    Heldin, C.H.4
  • 31
    • 0036713792 scopus 로고    scopus 로고
    • Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer
    • Sterner-Kock A, Thorey IS, Koli K, Wempe F, Otte J, Bangsow T, et al. Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. Genes Dev 2002 16 : 2264 73.
    • (2002) Genes Dev , vol.16 , pp. 2264-73
    • Sterner-Kock, A.1    Thorey, I.S.2    Koli, K.3    Wempe, F.4    Otte, J.5    Bangsow, T.6
  • 32
    • 5444255239 scopus 로고    scopus 로고
    • Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung
    • Koli K, Wempe F, Sterner-Kock A, Kantola A, Komor M, Hofmann WK, et al. Disruption of LTBP-4 function reduces TGF-beta activation and enhances BMP-4 signaling in the lung. J Cell Biol 2004 167 : 123 33.
    • (2004) J Cell Biol , vol.167 , pp. 123-33
    • Koli, K.1    Wempe, F.2    Sterner-Kock, A.3    Kantola, A.4    Komor, M.5    Hofmann, W.K.6
  • 33
    • 0034865421 scopus 로고    scopus 로고
    • Novel non-TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition
    • Koli K, Saharinen J, Karkkainen M, Keski-Oja J. Novel non-TGF-beta-binding splice variant of LTBP-4 in human cells and tissues provides means to decrease TGF-beta deposition. J Cell Sci 2001 114 : 2869 78.
    • (2001) J Cell Sci , vol.114 , pp. 2869-78
    • Koli, K.1    Saharinen, J.2    Karkkainen, M.3    Keski-Oja, J.4
  • 34
    • 0024389620 scopus 로고
    • Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2
    • Bascom CC, Wolfshohl JR, Coffey RJ Jr., Madisen L, Webb NR, Purchio AR, et al. Complex regulation of transforming growth factor beta 1, beta 2, and beta 3 mRNA expression in mouse fibroblasts and keratinocytes by transforming growth factors beta 1 and beta 2. Mol Cell Biol 1989 9 : 5508 15.
    • (1989) Mol Cell Biol , vol.9 , pp. 5508-15
    • Bascom, C.C.1    Wolfshohl, J.R.2    Coffey Jr., R.J.3    Madisen, L.4    Webb, N.R.5    Purchio, A.R.6
  • 35
    • 0024503360 scopus 로고
    • Regulation of epithelial cell proliferation by transforming growth factors
    • Bascom CC, Sipes NJ, Coffey RJ, Moses HL. Regulation of epithelial cell proliferation by transforming growth factors. J Cell Biochem 1989 39 : 25 32.
    • (1989) J Cell Biochem , vol.39 , pp. 25-32
    • Bascom, C.C.1    Sipes, N.J.2    Coffey, R.J.3    Moses, H.L.4
  • 37
    • 0027404055 scopus 로고
    • Immunoelectron microscopic localization of transforming growth factor beta 1 and latent transforming growth factor beta 1 binding protein in human gastrointestinal carcinomas: Qualitative difference between cancer cells and stromal cells
    • Mizoi T, Ohtani H, Miyazono K, Miyazawa M, Matsuno S, Nagura H. Immunoelectron microscopic localization of transforming growth factor beta 1 and latent transforming growth factor beta 1 binding protein in human gastrointestinal carcinomas: qualitative difference between cancer cells and stromal cells. Cancer Res 1993 53 : 183 90.
    • (1993) Cancer Res , vol.53 , pp. 183-90
    • Mizoi, T.1    Ohtani, H.2    Miyazono, K.3    Miyazawa, M.4    Matsuno, S.5    Nagura, H.6
  • 38
    • 0032415040 scopus 로고    scopus 로고
    • Cellular and extracellular biology of the latent transforming growth factor-beta binding proteins
    • Sinha S, Nevett C, Shuttleworth CA, Kielty CM. Cellular and extracellular biology of the latent transforming growth factor-beta binding proteins. Matrix Biol 1998 17 : 529 45.
    • (1998) Matrix Biol , vol.17 , pp. 529-45
    • Sinha, S.1    Nevett, C.2    Shuttleworth, C.A.3    Kielty, C.M.4


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