Methylation of the BIN1 gene promoter CpG island associated with breast and prostate cancer

Journal of Carcinogenesis

Volumn 6, Issue , 2007, Pages

  Kuznetsova, Ekaterina B ^a,b   Kekeeva, Tatiana V ^a,b   Larin, Sergei S ^c   Zemlyakova, Valeria V ^a,b   Khomyakova, Anastasiya V ^b   Babenko, Olga V ^a,b   Nemtsova, Marina V ^a,b   Zaletayev, Dmitry V ^a,b   Strelnikov, Vladimir V ^a,b  

^a RESEARCH CENTRE FOR MEDICAL GENETICS   (Russian Federation)

^b I M SECHENOV FIRST MOSCOW STATE MEDICAL UNIVERSITY   (Russian Federation)

^c INSTITUTE OF GENE BIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; BRIDGING INTEGRATOR 1 PROTEIN; PROTEIN BIN1; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL STRAIN LNCAP; CELL STRAIN MCF 7; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE; MALE; MICROSATELLITE MARKER; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROSTATE CANCER; REAL TIME POLYMERASE CHAIN REACTION;

EID: 34249812700     PISSN: None     EISSN: 14773163     Source Type: Journal    
DOI: 10.1186/1477-3163-6-9     Document Type: Article

References (18)

1. Sakamuro D Elliott KJ Wechsler-Reya R Prendergast GC BIN1 is a novel MYC-interacting protein with features of a tumour suppressor Nat Genet 1996 14 1 69-77 10.1038/ng0996-69 8782822
2. Kerangueven F Noguchi T Coulier F Allione F Wargniez V Simony-Lafontaine J Longy M Jacquemier J Sobol H Eisinger F Birnbaum D Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas Cancer Res 1997 57 5469-5474 9407952
3. Ge K Duhadaway J Sakamuro D Wechsler-Reya R Reynolds C Prendergast GC Losses of the tumor suppressor BIN1 in breast carcinoma are frequent and reflect deficits in programmed cell death capacity Int J Cancer 2000 85 3 376-383 10.1002/ (SICI)1097-0215(20000201)85:3<376::AID-IJC14>3.0.CO;2-1 10652430
4. Ge K Minhas F Duhadaway J Mao NC Wilson D Buccafusca R Sakamuro D Nelson P Malkowicz SB Tomaszewski J Prendergast GC Loss of heterozygosity and tumor suppressor activity of Bin1 in prostate carcinoma Int J Cancer 2000 86 2 155-161 10.1002/ (SICI)1097-0215(20000415)86:2<155::AID-IJC2>3.0.CO;2-M 10738240
5. Wechsler-Reya R Sakamuro D Zhang J Duhadaway J Prendergast GC Structural Analysis of the Human BIN1 Gene. Evidence for tissue-specific transcriptional regulation and alternate RNA splicing J Biol Chem 1997 272 31453-31458 10.1074/jbc.272.50.31453 9395479
6. Lodygin D Epanchintsev A Menssen A Diebold J Hermeking H Functional Epigenomics Identifies Genes Frequently Silenced in Prostate Cancer Cancer Res 2005 65 4218-4227 10.1158/0008-5472.CAN-04-4407 15899813
7. Liang G Gonzalgo ML Salem C Jones PA Identification of DNA methylation differences during tumorigenesis by methylation-sensitive arbitrarily primed polymerase chain reaction Methods 2002 27 2 150-155 10.1016/ S1046-2023(02)00068-3 12095274
8. Zemliakova VV Strel'nikov VV Zborovskaia IB Balukova OV Maiorova OA Vasil'ev EV Zaletaev DV Nemtsova MV Abnormal methylation of p16/CDKN2A AND p14/ARF genes GpG Islands in non-small cell lung cancer and in acute lymphoblastic leukemia Mol Biol (Mosk) 2004 38 6 966-972 15612580
9. Deng WH Wu YY Yang L Tang WQ Wang S Expression of estrogen sulfotransferase (EST) gene and bridging integrator protein-1 (BIN1) gene and their significance in breast tissues Ai Zheng 2004 23 11 1302-1305 15522178
10. Ge K DuHadaway J Du W Herlyn M Rodeck U Prendergast GC Mechanism for elimination of a tumor suppressor: Aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma PNAS 1999 96 9689-9694 22271 10449755 10.1073/pnas.96.17.9689
11. Tsutsumi M Tsai YC Gonzalgo ML Nichols PW Jones PA Early acquisition of homozygous deletions of p16/p19 during squamous cell carcinogenesis and genetic mosaicism in bladder cancer Oncogene 1998 17 23 3021-3027 10.1038/sj.onc.1202228 9881704
12. Abe M Okochi E Kuramoto T Kaneda A Takato T Sugimura T Ushijima T Cloning of the 5′ upstream region of the rat p16 gene and its role in silencing Jpn J Cancer Res 2002 93 10 1100-1106 12417039
13. Yan PS Shi H Rahmatpanah F Hsiau TH-C Hsiau AH-A Leu Y-W Liu JC Huang TH-M Differential Distribution of DNA Methylation within the RASSF1A CpG Island in Breast Cancer Cancer Res 2003 63 6178-6186 14559801
14. Deng G Chen A Hong J Chae HS Kim YS Methylation of CpG in a Small Region of the hMLH1 Promoter Invariably Correlates with the Absence of Gene Expression Cancer Res 1999 59 2029-2033 10232580
15. Miyakura Y Sugano K Konishi F Ichikawa A Maekawa M Shitoh K Igarashi S Kotake K Koyama Y Nagai H Extensive methylation of hMLH1 promoter region predominates in proximal colon cancer with microsatellite instability Gastroenterology 2001 121 6 1300-1309 10.1053/gast.2001.29616 11729109
16. Kaneda A Kaminishi M Yanagihara K Sugimura T Ushijima T Identification of Silencing of Nine Genes in Human Gastric Cancers Cancer Res 2002 62 6645-6650 12438262
17. Hagihara A Miyamoto K Furuta J Hiraoka N Wakazono K Seki S Fukushima S Tsao MS Sugimura T Ushijima T Identification of 27 5′ CpG islands aberrantly methylated and 13 genes silenced in human pancreatic cancers Oncogene 2004 23 53 8705-8710 10.1038/sj.onc.1207783 15467763
18. Ushijima T Detection and interpretation of altered methylation patterns in cancer cells Nat Rev Cancer 2005 5 3 223-231 10.1038/nrc1571 15719030