Inhibin A, inhibin B and activin A in the follicular fluid of regularly cycling women

Human Reproduction

Volumn 12, Issue 8, 1997, Pages 1714-1719

  Magoffin, D A ^a,c   Jakimiuk, A J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDICAL UNIVERSITY OF LUBLIN   (Poland)

^c Department of Obstetrics ^*  (United States)

Author keywords

Activin; Follicular fluid; Inhibin; Ovary

Indexed keywords

ACTIVIN A; ANDROSTENEDIONE; ESTRADIOL; FOLLITROPIN; INHIBIN;

ADULT; ARTICLE; FEMALE; FOLLITROPIN RELEASE; HUMAN; NORMAL HUMAN; OVARY FOLLICLE DEVELOPMENT; OVARY FOLLICLE FLUID;

EID: 0030964535     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/12.8.1714     Document Type: Article

References (24)

1. Brailly, S., Gougeon, A., Milgrom, E. et al. (1981) Androgens and progestins in the human ovarian follicle: differences in the evolution of preovulatory, healthy nonovulatory, and atretic follicles. J. Clin. Endocrinol. Metab., 53, 128-134.
2. 2 induces inhibin-α and βA-subunit mRNA and secretion of dimeric inhibin A in cultured human granulosa-luteal cells. Mol. Hum. Reprod., 2, 815-822.
3. Erickson, G.F. Chung, D., Sit, A. et al. (1995) Follistatin concentrations in follicular fluid of normal and polycystic ovaries. Hum. Reprod., 10, 2120-2124.
4. Findlay, J.K. (1993) An update on the roles of inhibin, activin and follistatin as local regulators of folliculogenesis. Biol. Reprod., 48, 15-23.
5. Franchimont, P., Hazee-Hagelstein, M.T., Charlet-Renand, C. et al. (1990) Correlation between follicular fluid content and the results of in vitro fertilization and embryo transfer. II. Inhibin and aromatase inhibitor activity. J. Clin. Endocrinol. Metab., 71, 748-754.
6. Fraser, H.M., Tsonis, C.G. (1994) Manipulation of inhibin during the lutealfollicular phase transition of the primate menstrual cycle fails to affect FSH secretion. J. Endocrinol., 142, 181-186.
7. Groome, N.P., Illingworth, P.J., O'Brien, M. et al. (1994) Detection of dimeric inhibin throughout the human menstrual cycle by two-site enzyme immunoassay. Clin. Endocrinol. (Oxf), 40, 717-723.
8. Groome, N.P., Illingworth, P.J., O'Brien, M. et al. (1996) Measurement of dimeric inhibin B throughout the human menstrual cycle. J. Clin. Endocrinol. Metab., 81, 1401-1405.
9. Hillier, S.G. (1991) Regulatory functions for inhibin and activin in human ovaries. J. Endocrinol, 131, 171-175.
10. Hillier, S.G., Yong, E.L., Illingworth, P.J. et al. (1991) Effect of recombinant inhibin on androgen synthesis in cultured human thecal cells. Molec. Cell Endocrinol., 75, Rl-6.
11. Hsueh, A.J.W., Dahl, K.D., Vaughan, J. et al. (1987) Heterodimers and homodimers of inhibin subunits have different paracrine action in the modulation of luteinizing hormone-stimulated androgen biosynthesis. Proc. Natl Acad. Sci. USA, 84, 5082-5086.
12. Magoffin, D.A. and Erickson, G.F. (1982) Primary culture of differentiating ovarian androgen-producing cells in defined medium. J. Biol Chem., 257, 4507-513.
13. McNatty, K.P. and Baird, D.T. (1978) Relationship between follicle-stimulating hormone, androstenedione and oestradiol in human follicular fluid. J. Endocrinol., 76, 527-531.
14. McNatty, K.P., Hunter, W.M., McNeilly, A.S. et al. (1975) Changes in the concentration of pituitary and steroid hormones in the follicular fluid of human graafian follicles throughout the menstrual cycle. J. Endocrinol., 64, 555-571.
15. McNatty, K.P., Smith, D.M., Makris, A. et al. (1979) The microenvironment of the human antral follicle: interrelationships among the steroid levels in antral fluid, the population of granulosa cells, and the status of the oocyte in vivo and in vitro. J. Clin. Endocrinol Metab., 49, 851-860.
16. McNeilly, A.S., Crow, W. and Campbell, B.K. (1991) Effect of follicular fluid and inhibin immunoneutralization on FSH-induced preovulatory follicle growth in the ewe. J. Endocrinol, 131, 401-409.
17. Miro, F. and Hillier, S.G. (1992) Relative effects of activin and inhibin on steroid hormone synthesis in primate granulosa cells. J. Clin. Endocrinol Metab., 75, 1556-1561.
18. Miyanaga, K., Erickson, G.F., DePaolo, L.V. et al. (1993) Differential control of activin, inhibin and follistatin proteins in cultured rat granulosa cells. Biochem. Biophys. Res. Commun., 194, 253-258.
19. Muttukrishna, S., Fowler, P.A., George, L. et al. (1996) Changes in peripheral serum levels of total activin A during the human menstrual cycle and pregnancy. J. Clin. Endocrinol Metab., 81, 3328-3334,
20. Smyth, C.D., Miro, F., Whitelaw, P.F. et al. (1993) Ovarian thecal/interstitial androgen synthesis is enhanced by a follicle-stimulating hormone-stimulated paracrine mechanism. Endocrinology, 133, 1532-1538.
21. Smyth, C.D., Gosden, R.G., McNeilly, A.S. et al. (1994) Effect of inhibin immunoneutralization on steroidogenesis in rat ovarian follicles in vitro. J. Endocrinol., 140, 437-443.
22. Woodruff, T.K., Lyon, R.J., Hansen, S.E. et al. (1990) Inhibin and activin locally regulate rat ovarian folliculogenesis. Endocrinology, 127, 3196-3205.
23. Zachow, R J. and Magoffin, D.A. (1995) Granulosa cell modulation of luteinizing hormone-dependent androgen production by ovarian thecainterstitial cells: a temporal switch from suppression to augmentation stimulated by follicle-stimulating hormone in vitro. Biol. Reprod., 3, 758-765.
24. Zeleznik, A.J. and Fairchild-Benyo, D. (1994) Control of follicular development, corpus luteum function, and the recognition of pregnancy in higher primates. In Knobil, E. and Neill, J.D. (eds), The Physiology of Reproduction. Raven Press, New York, p. 751.