Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells

Human Gene Therapy

Volumn 18, Issue 5, 2007, Pages 413-422

  Kobinger, Gary P ^a,b   Limberis, Maria P ^c   Somanathan, Suri ^c   Schumer, Gregory ^d   Bell, Peter ^c   Wilson, James M ^c,e  

^a PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d Hydrobiotech   (Canada)

^e Translational Research Laboratories   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; COMPLEMENTARY DNA; CYTOKINE; HUMAN IMMUNODEFICIENCY VIRUS VECTOR; LENTIVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; VIRUS RNA; VIRUS SPIKE PROTEIN; VIRUS VECTOR; ZIDOVUDINE;

AIRWAY; ALPHA 1 ANTITRYPSIN DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; DENDRITIC CELL; ELECTRON MICROSCOPY; EPITHELIUM CELL; GENE TRANSFER; GENETIC DISORDER; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; LUNG DISEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROMOTER REGION; PROTEIN EXPRESSION; RESPIRATORY EPITHELIUM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SARS CORONAVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; TRANSGENE; VIRAL RESPIRATORY TRACT INFECTION; VIRUS ENVELOPE; VIRUS VIRULENCE; WESTERN BLOTTING;

ANIMALS; CELLS, CULTURED; DENDRITIC CELLS; EPITHELIAL CELLS; GENE THERAPY; GENETIC VECTORS; HIV; HUMANS; LAC OPERON; LUNG DISEASES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; RESPIRATORY SYSTEM; SARS VIRUS; TRANSDUCTION, GENETIC; VIRAL ENVELOPE PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS; MURINAE; SARS CORONAVIRUS; ZAIRE EBOLAVIRUS;

EID: 34249787358     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2006.194     Document Type: Article

References (33)

1. BABCOCK, G.J., ESSHAKI, D.J., THOMAS, W.D., Jr., and AMBROSINO, D.M. (2004). Amino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor. J. Virol. 78, 4552-4560.
2. BLOMER, U., NALDINI, L., KAFRI, T., TRONO, D., VERMA, I.M., and GAGE, F.H. (1997). Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector. J. Virol. 71, 6641-6649.
3. DROSTEN, C., GUNTHER, S., PREISER, W., VAN DER WERF, S., BRODT, H.R., BECKER, S., RABENAU, H., PANNING, M., KOLESNIKOVA, L., FOUCHIER, R.A., BERGER, A., BURGUIERE, A.M., CINATL, J., EICKMANN, M., ESCRIOU, N., GRYWNA, K., KRAMME, S., MANUGUERRA, J.C., MULLER, S., RICKERTS, V., STURMER, M., VIETH, S., KLENK, H.D., OSTERHAUS, A.D., SCHMITZ, H., and DOERR, H.W. (2003). Identification of a novel coronavirus in patients with severe acute respiratory syndrome. N. Engl. J. Med. 348, 1967-1976.
4. FRANKS, T.J., CHONG, P.Y., CHUI, P., GALVIN, J.R., LOURENS, R.M., REID, A.H., SELBS, E., McEVOY, C.P., HAYDEN, C.D., FUKUOKA, J., TAUBENBERGER, J.K., and TRAVIS, W.D. (2003). Lung pathology of severe acute respiratory syndrome (SARS): A study of 8 autopsy cases from Singapore. Hum. Pathol. 34, 743-748.
5. HAMMING, I., TIMENS, W., BULTHUIS, M.L., LELY, A.T., NAVIS, G.J., and VAN GOOR, H. (2004). Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus: A first step in understanding SARS pathogenesis. J. Pathol. 203, 631-637.
6. HOFMANN, H., HATTERMANN, K., MARZI, A., GRAMBERG, T., GEIER, M., KRUMBIEGEL, M., KUATE, S., UBERLA, K., NIEDRIG, M., and POHLMANN, S. (2004). S protein of severe acute respiratory syndrome-associated coronavirus mediates entry into hepatoma cell lines and is targeted by neutralizing antibodies in infected patients. J. Virol. 78, 6134-6142.
7. HOFMANN, H., and POHLMANN, S. (2004). Cellular entry of the SARS coronavirus. Trends Microbiol. 12, 466-472.
8. HOGAN, R.J., GAO, G., ROWE, T., BELL, P., FLIEDER, D., PARAGAS, J., KOBINGER, G.P., WIVEL, N.A., CRYSTAL, R.G., BOYER, J., FELDMANN, H., VOSS, T.G., and WILSON, J.M. (2004). Resolution of primary severe acute respiratory syndrome-associated coronavirus infection requires Statl. J. Virol. 78, 11416-11421.
9. JIA, H.P., LOOK, D.C., SHI, L., HICKEY, M., PEWE, L., NETLAND, J., FARZAN, M., WOHLFORD-LENANE, C., PERLMAN, S., and McCRAY, P.B., Jr. (2005). ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J. Virol. 79, 14614-14621.
10. JOHNSON, L.G., OLSEN, J.C., NALDINI, L., and BOUCHER, R.C. (2000). Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo. Gene Ther. 7, 568-574.
11. KOBINGER, G.P., WEINER, D.J., YU, Q.C., and WILSON, J.M. (2001). Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo. Nat. Biotechnol. 19, 225-230.
12. LEE, N., HUI, D., WU, A., CHAN, P., CAMERON, P., JOYNT, G.M., AHUJA, A., YUNG, M.Y., LEUNG, C.B., TO, K.F., LUI, S.F., SZETO, C.C., CHUNG, S., and SUNG, J.J. (2003). A major outbreak of severe acute respiratory syndrome in Hong Kong. N. Engl. J. Med. 348, 1986-1994.
13. LI, W., MOORE M.J., VASILIEVA, N., SUI, J., WONG, S.K., BERNE, M.A., SOMASUNDARAN, M., SULLIVAN, J.L., LUZURIAGA, K., GREENOUGH, T.C., CHOE, H., and FARZAN, M. (2003). Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus. Nature 426, 450-454.
14. LI, X., MUKAI, T., YOUNG, D., FRANKEL, S., LAW, P., and WONG-STAAL, F. (1998). Transduction of CD34+ cells by a vesicular stomach virus protein G (VSV-G) pseudotyped HIV-1 vector: Stable gene expression in progeny cells, including dendritic cells. J. Hum. Virol. 1, 346-352.
15. LIMBERIS, M., ANSON, D.S., FULLER, M., and PARSONS, D.W. (2002). Recovery of airway cystic fibrosis transmembrane conductance regulator function in mice with cystic fibrosis after single-dose lentivirus-mediated gene transfer. Hum. Gene Ther. 13, 1961-1970.
16. MARRA, M.A., JONES, S.J., ASTELL, C.R., HOLT, R.A., BROOKS-WILSON, A., BUTTERFIELD, Y.S., KHATTRA, J., ASANO, J.K., BARBER, S.A., CHAN, S.Y., CLOUTIER, A., COUGHLIN, S.M., FREEMAN, D., GIRN, N., GRIFFITH, O.L., LEACH, S.R., MAYO, M., MCDONALD, H., MONTGOMERY, S.B., PANDOH, P.K., PETRESCU, A.S., ROBERTSON, A.G., SCHEIN, J.E., SIDDIQUI, A., SMAILUS, D.E., STOTT, J.M., YANG, G.S., PLUMMER, F., ANDONOV, A., ARTSOB, H., BASTIEN, N., BERNARD, K., BOOTH, T.F., BOWNESS, D., CZUB, M., DREBOT, M., FERNANDO, L., FLICK, R., GARBUTT, M., GRAY, M., GROLLA, A., JONES, S., FELDMANN, H., MEYERS, A., KABANI, A., LI, Y., NORMAND, S., STROHER, U., TIPPLES, G.A., TYLER, S., VOGRIG, R., WARD, D., WATSON, B., BRUNHAM, R.C., KRAJDEN, M., PETRIC, M., SKOWRONSKI, D.M., UPTON, C., and ROPER, R.L. (2003). The genome sequence of the SARS-associated coronavirus. Science 300, 1399-1404.
17. MEDINA, M.F., KOBINGER, G.P., RUX, J., GASMI, M., LOONEY, D.J., BATES, P., and WILSON, J.M. (2003). Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. Mol. Ther. 8, 777-789.
18. MILLER, G., LAHRS, S., SHAH, A.B., and DEMATTEO, R.P. (2003). Optimization of dendritic cell maturation and gene transfer by recombinant adenovirus. Cancer Immunol Immunother 52, 347-358.
19. MIYOSHI, H., TAKAHASHI, M., GAGE, F.H., and VERMA, I.M. (1997). Stable and efficient gene transfer into the retina using an HIV-based lentiviral vector. Proc. Natl. Acad. Sci. U.S.A. 94, 10319-10323.
20. MOORE, M.J., DORFMAN, T., LI, W., WONG, S.K., LI, Y., KUHN, J.H., CODERRE, J., VASILIEVA, N., HAN, Z., GREENOUGH, T.C., FARZAN, M., and CHOE, H. (2004). Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2. J. Virol. 78, 10628-10635.
21. NALDINI, L., BLOMER, U., GALLAY, P., ORY, D., MULLIGAN, R., GAGE, F.H., VERMA, I.M., and TRONO, D. (1996). In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 272, 263-267.
22. NICHOLLS, J.M., BUTANY, J., POON, L.L., CHAN, K.H., BEH, S.L., POUTANEN, S., PEIRIS, J.S., and WONG, M. (2006). Time course and cellular localization of SARS-CoV nucleoprotein and RNA in lungs from fatal cases of SARS. PLoS Med. 3, e27.
23. NIWA, H., YAMAMURA, K., and MIYAZAKI, J. (1991). Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193-199.
24. SIMS, A.C., BARIC, R.S., YOUNT, B., BURKETT, S.E., COLLINS, P.L., and PICKLES, R.J. (2005). Severe acute respiratory syndrome coronavirus infection of human ciliated airway epithelia: Role of ciliated cells in viral spread in the conducting airways of the lungs. J. Virol. 79, 15511-15524.
25. SINN, P.L., BURNIGHT, E.R., SHEN, H., FAN, H., and McCRAY, P.B., Jr. (2005). Inclusion of Jaagsiekte sheep retrovirus proviral elements markedly increases lentivirus vector pseudotyping efficiency. Mol. Ther. 11, 460-469.
26. SPIEGEL, M., SCHNEIDER, K., WEBER, F., WEIDMANN, M., and HUFERT, F.T. (2006). Interaction of severe acute respiratory syndrome-associated coronavirus with dendritic cells. J. Gen. Virol. 87, 1953-1960.
27. SUBBARAO, K., McAULIFFE, J., VOGEL, L., FAHLE, G., FISCHER, S., TATTI, K., PACKARD, M., SHIEH, W.J., ZAKI, S., and MURPHY, B. (2004). Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice. J. Virol. 78, 3572-3577.
28. TASSANEETRITHEP, B., BURGESS, T.H., GRANELLI-PIPERNO, A., TRUMPFHELLER, C., FINKE, J., SUN, W., ELLER, M.A., PATTANAPANYASAT, K., SARASOMBATH, S., BIRX, D.L., STEINMAN, R.M., SCHLESINGER, S., and MAROVICH, M.A. (2003). DC-SIGN (CD209) mediates dengue virus infection of human dendritic cells. J. Exp. Med. 197, 823-829.
29. WATSON, D.J., KOBINGER, G.P., PASSINI, M.A., WILSON, J.M., and WOLFE, J.H. (2002). Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins. Mol. Ther. 5, 528-537.
30. YANG, Z.Y., HUANG, Y., GANESH, L., LEUNG, K., KONG, W.P., SCHWARTZ, O., SUBBARAO, K., and NABEL, G.J. (2004). pH-dependent entry of severe acute respiratory syndrome coronavirus is mediated by the spike glycoprotein and enhanced by dendritic cell transfer through DC-SIGN. J. Virol. 78, 5642-5650.
31. YEN, Y.T., LIAO, F., HSIAO, C.H., KAO, C.L., CHEN, Y.C., and WU-HSIEH, B.A. (2006). Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro. J. Virol. 80, 2684-2693.
32. ZHI, Y., KOBINGER, G.P., JORDAN, H., SUCHMA, K., WEISS, S.R., SHEN, H., SCHUMER, G., GAO, G., BOYER, J.L., CRYSTAL, R.G., and WILSON, J.M. (2005). Identification of murine CD8 T cell epitopes in codon-optimized SARS-associated coronavirus spike protein. Virology 335, 34-45.
33. ZIEGLER, T., MATIKAINEN, S., RONKKO, E., OSTERLUND, P., SILLANPAA, M., SIREN, J., FAGERLUND, R., IMMONEN, M., MELEN, K., and JULKUNEN, I. (2005). Severe acute respiratory syndrome coronavirus fails to activate cytokine-mediated innate immune responses in cultured human monocyte-derived dendritic cells. J. Virol. 79, 13800-13805.