Quantum dot-based sensor for improved detection of apoptotic cells

Nanomedicine

Volumn 2, Issue 1, 2007, Pages 71-78

  Koeppel, Florence ^a   Jaiswal, Jyoti K ^a   Simon, Sanford M ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Annexin A5; Apoptosis; Conjugation; Live cell imaging; Probe; Quantum dots

Indexed keywords

LIPOCORTIN 5; NANOPARTICLE; PHOSPHATIDYLSERINE; QUANTUM DOT; STAUROSPORINE;

APOPTOSIS; ARTICLE; CELL ASSAY; CELL MEMBRANE; CELL SCREENING; CELL STRUCTURE; HUMAN; HUMAN CELL; IMAGE QUALITY; INTERMETHOD COMPARISON; NON INVASIVE PROCEDURE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ANNEXIN A5; APOPTOSIS; BIOSENSING TECHNIQUES; CELL MEMBRANE; HELA CELLS; HUMANS; IMAGE ENHANCEMENT; MATERIALS TESTING; MICROSCOPY, FLUORESCENCE; PHOSPHATIDYLSERINES; QUANTUM DOTS;

EID: 34249785370     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/17435889.2.1.71     Document Type: Article

References (20)

1. Fadeel B, Orrenius S: Apoptosis: a basic biological phenomenon with wideranging implications in human disease. J. Intern. Med. 258, 479-517 (2005).
2. Rich T, Watson CJ, Wyllie A: Apoptosis: the germs of death. Nat. Cell Biol. 1, E69-E71 (1999).
3. Kietselaer BL, Hofstra L, Dumont EA, Reutelingsperger CP, Heidendal GA: The role of labeled Annexin A5 in imaging of programmed cell death. From animal to clinical imaging. Q. J. Nucl. Med. 47, 349-361 (2003).
4. Jaiswal JK, Simon SM: Potentials and pitfalls of fluorescent quantum dots for biological imaging. Trends Cell Biol. 14, 497-504 (2004).
5. Michalet X, Pinaud FF, Bentolila LA et al.: Quantum dots for live cells, in vivo imaging, and diagnostics. Science 307, 538-544 (2005).
6. Jaiswal JK, Mattoussi H, Mauro JM, Simon SM: Long-term multiple color imaging of live cells using quantum dot bioconjugates. Nat. Biotechnol. 21, 47-51 (2003).
7. Ballou B, Lagerholm BC, Ernst LA, Bruchez MP, Waggoner AS: Noninvasive imaging of quantum dots in mice. Bioconjug. Chem. 15, 79-86 (2004).
8. Gao X. Cui Y, Levenson RM, Chung LW, Nie S: In vivo cancer targeting and imaging with semiconductor quantum dots. Nat. Biotechnol. 22, 969-976 (2004).
9. Kim S, Lim YT, Soltesz EG et al.: Near-infrared fluorescent type II quantum dots for sentinel lymph node mapping. Nat. Biotechnol. 22, 93-97 (2004).
10. Larson DR, Zipfel WR, Williams RM et al.: Water-soluble quantum dots for multiphoton fluorescence imaging in vivo. Science 300, 1434-1436 (2003).
11. Voura EB, Jaiswal JK, Mattoussi H, Simon SM: Tracking metastatic tumor cell extravasation with quantum dot nanocrystals and fluorescence emission-scanning microscopy. Nat. Med. 10, 993-998 (2004).
12. Zhang Y, So MK, Loening AM, Yao H, Gambhir SS, Rao J: Halo Tag protein-mediated site-specific conjugation of bioluminescent proteins to quantum dots. Angew. Chem. Int. Ed. Engl. 45, 4936-4940 (2006).
13. Mujumdar RB, Ernst LA, Mujumdar SR, Lewis CJ, Waggoner AS: Cyanine dye labeling reagents: sulfoindocyanine succinimidyl esters. Bioconjug. Chem. 4, 105-111 (1993).
14. Bertrand R, Solary E. O'Connor P, Kohn KW, Pommier Y: Induction of a common pathway of apoptosis by staurosporine. Exp. Cell Res. 211, 314-321 (1994).
15. Van Heerde WL, Sakariassen KS, Hemker HC, Sixma JJ, Reutelingsperger CP, de Groot PG: Annexin V inhibits the procoagulant activity of matrices of TNF-stimulated endothelium under blood flow conditions. Arterioscler. Tbromb. 14, 824-830 (1994).
16. Schellenberger EA, Weissleder R, Josephson L: Optimal modification of annexin V with fluorescent dyes. Chembiochem. 5, 271-274 (2004).
17. Le Gac S, Vermes I, van den Berg A: Quantum dots based probes conjugated to annexin V for photostable apoptosis detection and imaging. Nano Lett. 6(9), 1863-1869 (2006).
18. Wang GP, Song EQ, Xie HY et al.: Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications. Chem. Commun. (Camb.) 34, 4276-4278 (2005).
19. van Tilborg GA, Mulder WJ, Chin PT et al.: Annexin A5-conjugated quantum dots with a paramagnetic lipidic coating for the multimodal detection of apoptotic cells. Bioconjug. Chem. 17(4), 865-868 (2006).
20. Dumont EA, Reutelingsperger CP, Smits JF et al.: Real-time imaging of apoptotic cell-membrane changes at the single-cell level in the beating murine heart. Nat. Med. 7, 1352-1355 (2001).