Pharmacokinetics of trefoil peptides and their stability in gastrointestinal contents

Peptides

Volumn 28, Issue 6, 2007, Pages 1197-1206

  Kjellev, Stine ^a   Vestergaard, Else Marie ^b   Nexø, Ebba ^b   Thygesen, Peter ^a   Eghøj, Maria S ^c   Jeppesen, Palle B ^d   Thim, Lars ^a   Pedersen, Nis Borbye ^c   Poulsen, Steen Seier ^c  

^a NOVO NORDISK A S   (Denmark)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d Rigshospitalet   (Denmark)

Author keywords

Clearance; Pharmacokinetics; Stability; TFF2; TFF3; Trefoil factor family

Indexed keywords

TREFOIL FACTOR FAMILY 2; TREFOIL FACTOR FAMILY 3; TREFOIL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FECES ANALYSIS; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LARGE INTESTINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE; STOMACH JUICE;

ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FECES; FEMALE; GASTROINTESTINAL CONTENTS; HUMANS; INJECTIONS, INTRAMUSCULAR; INJECTIONS, INTRAPERITONEAL; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; MICE; MICE, INBRED BALB C; PEPTIDES; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

LOTUS; MUS; RATTUS;

EID: 34249782856     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2007.03.016     Document Type: Article

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