Reduction of Maternal Adrenal Steroids Results in Increased VEGF Protein Without Increased eNOS in the Ovine Placenta

Placenta

Volumn 28, Issue 7, 2007, Pages 658-667

  Jensen, E ^a   Wood, C E ^a   Keller Wood, M ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Cortisol; Fetus; Placentome

Indexed keywords

ALDOSTERONE; CORTICOSTEROID; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HYDROCORTISONE; MESSENGER RNA; VASCULOTROPIN;

ADRENAL DISEASE; ADRENALECTOMY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREEDING; CONTROLLED STUDY; EWE; FEMALE; FETOPLACENTAL UNIT; FETUS; FETUS (ANATOMY); GESTATIONAL AGE; HORMONE DETERMINATION; HYPOTHESIS; MORPHOLOGY; NONHUMAN; PLACENTA; PLACENTA PERFUSION; PRIORITY JOURNAL; PROTEIN ANALYSIS;

ALDOSTERONE; ANIMALS; FEMALE; HYDROCORTISONE; NITRIC OXIDE SYNTHASE TYPE III; PLACENTA; PREGNANCY; RNA, MESSENGER; SHEEP, DOMESTIC; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 34249777227     PISSN: 01434004     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.placenta.2006.09.005     Document Type: Article

References (41)

1. Carr B.R., Parker Jr. C.R., Madden J.D., MacDonald P.C., and Porter J.C. Maternal plasma adrenocorticotropin and cortisol relationships throughout human pregnancy. Am J Obstet Gynecol 139 (1981) 416-422
2. Bell M.E., Wood C.E., and Keller-Wood M. Influence of reproductive state on pituitary-adrenal activity in the ewe. Domest Anim Endocrinol 8 (1991) 245-254
3. Coe C.L., Murai J.T., Wiener S.G., Levine S., and Siiteri P.K. Rapid cortisol and corticosteroid-binding globulin responses during pregnancy and after estrogen administration in the squirrel monkey. Endocrinology 118 (1986) 435-440
4. Jensen E., Wood C.E., and Keller-Wood M. Chronic alterations in ovine maternal corticosteroid influence uterine blood flow and placental and fetal growth. Am J Physiol Regul Integr Comp Physiol 288 (2005) R54-R61
5. Jensen E., Wood C., and Keller-Wood M. The normal increase in adrenal secretion during pregnancy contributes to maternal volume expansion and fetal homeostasis. J Soc Gynecol Investig 9 (2002) 362-371
6. Vatnick I., Schoknecht P.A., Darrigrand R., and Bell A.W. Growth and metabolism of the placenta after unilateral fetectomy in twin pregnant ewes. J Dev Physiol 15 (1991) 351-356
7. Alexander G. Studies on the placenta of the sheep (Ovis aries L.). Placental size. J Reprod Fertil 30 (1964) 289-305
8. Reynolds L.P., Borowicz P.P., Vonnahme K.A., Johnson M.L., Grazul-Bilska A.T., Redmer D.A., et al. Placental angiogenesis in sheep models of compromised pregnancy. J Physiol 565 (2005) 43-58
9. Reynolds L.P., and Redmer D.A. Angiogenesis in the placenta. Biol Reprod 64 (2001) 1033-1040
10. Steyn C., Hawkins P., Saito T., Noakes D.E., Kingdom J.C., and Hanson M.A. Under nutrition during the first half of gestation increases the predominance of fetal tissue in late-gestation ovine placentomes. Eur J Obstet Gynecol Reprod Biol 98 (2001) 165-170
11. Penninga L., and Longo L.D. Ovine placentome morphology: effect of high altitude, long-term hypoxia. Placenta 19 (1998) 187-193
12. Heasman L., Clarke L., Firth K., Stephenson T., and Symonds M.E. Influence of restricted maternal nutrition in early to mid gestation on placental and fetal development at term in sheep. Pediatr Res 44 (1998) 546-551
13. Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25 (2004) 581-611
14. Zheng J., Li Y., Weiss A.R., Bird I.M., and Magness R.R. Expression of endothelial and inducible nitric oxide synthases and nitric oxide production in ovine placental and uterine tissues during late pregnancy. Placenta 21 (2000) 516-524
15. Sladek S.M., Magness R.R., and Conrad K.P. Nitric oxide and pregnancy. Am J Physiol 272 (1997) R441-R463
16. Papapetropoulos A., Garcia-Cardena G., Madri J.A., and Sessa W.C. Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells. J Clin Invest 100 (1997) 3131-3139
17. Ziche M., Morbidelli L., Choudhuri R., Zhang H.T., Donnini S., Granger H.J., et al. Nitric oxide synthase lies downstream from vascular endothelial growth factor-induced but not basic fibroblast growth factor-induced angiogenesis. J Clin Invest 99 (1997) 2625-2634
18. Jensen E., Wood C.E., and Keller-Wood M. Alterations in maternal corticosteroid levels influence fetal urine and lung liquid production. J Soc Gynecol Investig 10 (2003) 480-489
19. Keller-Wood M., Cudd T.A., Norman W., Caldwell S.M., and Wood C.E. Sheep model for study of maternal adrenal gland function during pregnancy. Lab Anim Sci 48 (1998) 507-512
20. Cheung C.Y., and Brace R.A. Ovine vascular endothelial growth factor: nucleotide sequence and expression in fetal tissues. Growth Factors 16 (1998) 11-22
21. Cheung C.Y., Singh M., Ebaugh M.J., and Brace R.A. Vascular endothelial growth factor gene expression in ovine placenta and fetal membranes. Am J Obstet Gynecol 173 (1995) 753-759
22. Livak K.J., and Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25 (2001) 402-408
23. Ward J.W., Forhead A.J., Wooding F.B., and Fowden A.L. Functional significance and cortisol dependence of the gross morphology of ovine placentomes during late gestation. Biol Reprod (2005)
24. Barcroft J., and Kennedy J.A. The distribution of blood flow between the foetus and placenta in sheep. J Physiol 95 (1939) 173-186
25. Cheung C.Y., and Brace R.A. Developmental expression of vascular endothelial growth factor and its receptors in ovine placenta and fetal membranes. J Soc Gynecol Investig 6 (1999) 179-185
26. Gaillard I., Keramidas M., Liakos P., Vilgrain I., Feige J.J., and Vittet D. ACTH-regulated expression of vascular endothelial growth factor in the adult bovine adrenal cortex: a possible role in the maintenance of the microvasculature. J Cell Physiol 185 (2000) 226-234
27. Shifren J.L., Mesiano S., Taylor R.N., Ferrara N., and Jaffe R.B. Corticotropin regulates vascular endothelial growth factor expression in human fetal adrenal cortical cells. J Clin Endocrinol Metab 83 (1998) 1342-1347
28. Koedam J.A., Smink J.J., and van Buul-Offers S.C. Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes. Mol Cell Endocrinol 197 (2002) 35-44
29. Matsumoto L.C., Bogic L., Brace R.A., and Cheung C.Y. Prolonged hypoxia upregulates vascular endothelial growth factor messenger RNA expression in ovine fetal membranes and placenta. Am J Obstet Gynecol 186 (2002) 303-310
30. Regnault T.R., Orbus R.J., de Vrijer B., Davidsen M.L., Galan H.L., Wilkening R.B., et al. Placental expression of VEGF, PlGF and their receptors in a model of placental insufficiency-intrauterine growth restriction (PI-IUGR). Placenta 23 (2002) 132-144
31. Regnault T.R., de Vrijer B., Galan H.L., Davidsen M.L., Trembler K.A., Battaglia F.C., et al. The relationship between transplacental O2 diffusion and placental expression of PlGF, VEGF and their receptors in a placental insufficiency model of fetal growth restriction. J Physiol 550 (2003) 641-656
32. Bouloumie A., Schini-Kerth V.B., and Busse R. Vascular endothelial growth factor up-regulates nitric oxide synthase expression in endothelial cells. Cardiovasc Res 41 (1999) 773-780
33. Kimura H., and Esumi H. Reciprocal regulation between nitric oxide and vascular endothelial growth factor in angiogenesis. Acta Biochim Pol 50 (2003) 49-59
34. Zheng J., Wen Y., Austin J.L., and Chen D.B. Exogenous nitric oxide stimulates cell proliferation via activation of a mitogen-activated protein kinase pathway in ovine fetoplacental artery endothelial cells. Biol Reprod (2005)
35. Galan H.L., Regnault T.R., Le Cras T.D., Tyson R.W., Anthony R.V., Wilkening R.B., et al. Cotyledon and binucleate cell nitric oxide synthase expression in an ovine model of fetal growth restriction. J Appl Physiol 90 (2001) 2420-2426
36. Aida K., Wang X.L., Wang J., Li C., McDonald T.J., and Nathanielsz P.W. Effect of betamethasone administration to the pregnant baboon at 0.75 gestation on placental eNOS distribution and activity. Placenta 25 (2004) 780-787
37. Poppa V., Miyashiro J.K., Corson M.A., and Berk B.C. Endothelial NO synthase is increased in regenerating endothelium after denuding injury of the rat aorta. Arterioscler Thromb Vasc Biol 18 (1998) 1312-1321
38. Li Y., Zheng J., Bird I.M., and Magness R.R. Effects of pulsatile shear stress on nitric oxide production and endothelial cell nitric oxide synthase expression by ovine fetoplacental artery endothelial cells. Biol Reprod 69 (2003) 1053-1059
39. Nadaud S., Philippe M., Arnal J.F., Michel J.B., and Soubrier F. Sustained increase in aortic endothelial nitric oxide synthase expression in vivo in a model of chronic high blood flow. Circ Res 79 (1996) 857-863
40. Kingdom J. Adriana and Luisa Castellucci Award Lecture 1997. Placental pathology in obstetrics: adaptation or failure of the villous tree?. Placenta 19 (1998) 347-351
41. Fox H. Pathology of the placenta. Clin Obstet Gynaecol 13 (1986) 501-519