Synthesis of a novel 'smart' bifunctional chelating agent 1-(2-[β,d-galactopyranosyloxy]ethyl)-7-(1-carboxy-3-[4-aminophenyl]propyl)-4,10-bis(carboxymethyl)-1,4,7,10-tetraazacyclododecane (Gal-PA-DO3A-NH2) and its Gd(III) complex

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 14, 2007, Pages 4714-4721

  Wardle, Nick J ^a   Herlihy, Amy H ^b   So, Po Wah ^b   Bell, Jimmy D ^b   Bligh, S W Annie ^a  

^a LONDON METROPOLITAN UNIVERSITY   (United Kingdom)

^b MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

Author keywords

Contrast agents; DO3A; Gd(III) complex; MRI

Indexed keywords

1 [2 (BETA DEXTRO GALACTOPYRANOSYLOXY)ETHYL] 4,7,10 TRIS(CARBOXYMETHYL) 1, 4,7,10 TETRAAZACYCLODODECANE; 1 [2 (BETA DEXTRO GALACTOPYRANOSYLOXY)ETHYL] 7 [1 CARBOXY 3 (4 AMINOPHENYL)PROPYL] 4,10 BIS(CARBOXYMETHYL) 1,4,7,10 TETRAAZACYCLODODECANE; CHELATING AGENT; GADOLINIUM; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; STOICHIOMETRY;

CHELATING AGENTS; GADOLINIUM; HETEROCYCLIC COMPOUNDS, 1-RING; LIGANDS; MOLECULAR STRUCTURE; PROTONS;

EID: 34249746220     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.05.004     Document Type: Article

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