메뉴 건너뛰기




Volumn 83, Issue 1, 2007, Pages 104-111

Assessment of hepatocellular damage and hematological alterations in mice chronically fed p-dimethyl aminoazobenzene and phenobarbital

Author keywords

Carcinogenesis; Hemoglobin; Hormone; Matrix metalloproteinase; p dimethyl aminoazobenzene; Phenobarbital; Reduced glutathione; Restriction endonuclease; Scanning electron microscopy; Transmission electron microscopy

Indexed keywords

4 DIMETHYLAMINOAZOBENZENE; CHOLESTEROL; ESTRADIOL; GLUCOSE; GLUTATHIONE; HEMOGLOBIN; HYDROCORTISONE; MATRIX METALLOPROTEINASE; PHENOBARBITAL; TESTOSTERONE;

EID: 34249735959     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2006.10.003     Document Type: Article
Times cited : (25)

References (67)
  • 1
    • 0014293865 scopus 로고
    • Induction of hepatoma and systemic amyloidosis in mice by 4-(dimethylamino) azobenezene feeding
    • Akamatsu Y., and Ikegami R. Induction of hepatoma and systemic amyloidosis in mice by 4-(dimethylamino) azobenezene feeding. Gann 59 (1968) 201-206
    • (1968) Gann , vol.59 , pp. 201-206
    • Akamatsu, Y.1    Ikegami, R.2
  • 2
    • 0026039082 scopus 로고
    • Human fibroblasts contain a proteolytic activity which is inhibited by the Bowman-Birk protease inhibitor
    • Billings P.C., Habres J.M., Liao D.C., and Tuttle S.W. Human fibroblasts contain a proteolytic activity which is inhibited by the Bowman-Birk protease inhibitor. Cancer Res. 51 (1991) 5539-5543
    • (1991) Cancer Res. , vol.51 , pp. 5539-5543
    • Billings, P.C.1    Habres, J.M.2    Liao, D.C.3    Tuttle, S.W.4
  • 3
    • 0029150795 scopus 로고
    • Proteolytic remodeling of extracellular matrix
    • Birkedal-Hansen H. Proteolytic remodeling of extracellular matrix. Curr. Opin. Cell Biol. 7 (1995) 728-735
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 728-735
    • Birkedal-Hansen, H.1
  • 4
    • 3042805454 scopus 로고    scopus 로고
    • Evaluation of protective potentials of a homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice. Indian
    • Biswas S.J., and Khuda-Bukhsh A.R. Evaluation of protective potentials of a homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice. Indian. J. Exp. Biol. 42 (2004) 698-714
    • (2004) J. Exp. Biol. , vol.42 , pp. 698-714
    • Biswas, S.J.1    Khuda-Bukhsh, A.R.2
  • 5
    • 27144502020 scopus 로고    scopus 로고
    • Cytotoxic and genotoxic effects of the azo-dye p-dimethylaminoazobenzene in mice: a time-course study
    • Biswas S.J., and Khuda-Bukhsh A.R. Cytotoxic and genotoxic effects of the azo-dye p-dimethylaminoazobenzene in mice: a time-course study. Mutat. Res. 587 (2005) 1-8
    • (2005) Mutat. Res. , vol.587 , pp. 1-8
    • Biswas, S.J.1    Khuda-Bukhsh, A.R.2
  • 6
    • 8644283540 scopus 로고    scopus 로고
    • Assessment of the genotoxic and cytotoxic potential of an anti-epileptic drug, phenobarbital, in mice: a time course study
    • Biswas S.J., Pathak S., and Khuda-Bukhsh A.R. Assessment of the genotoxic and cytotoxic potential of an anti-epileptic drug, phenobarbital, in mice: a time course study. Mutat. Res. 563 (2004) 1-11
    • (2004) Mutat. Res. , vol.563 , pp. 1-11
    • Biswas, S.J.1    Pathak, S.2    Khuda-Bukhsh, A.R.3
  • 7
    • 0033573946 scopus 로고    scopus 로고
    • Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer: study of Osteoporotic Fractures Research Group
    • Cauley J.A., Lucas F.L., Kuller L.H., Stone K., Browner W., and Cummings S.R. Elevated serum estradiol and testosterone concentrations are associated with a high risk for breast cancer: study of Osteoporotic Fractures Research Group. Ann. Intern. Med. 130 (1999) 270-277
    • (1999) Ann. Intern. Med. , vol.130 , pp. 270-277
    • Cauley, J.A.1    Lucas, F.L.2    Kuller, L.H.3    Stone, K.4    Browner, W.5    Cummings, S.R.6
  • 8
    • 0031695507 scopus 로고    scopus 로고
    • Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens
    • Christensen J., Gonzales A., Cattley R., and Goldsworthy T. Regulation of apoptosis in mouse hepatocytes and alteration of apoptosis by nongenotoxic carcinogens. Cell Growth Differ. 9 (1998) 815-825
    • (1998) Cell Growth Differ. , vol.9 , pp. 815-825
    • Christensen, J.1    Gonzales, A.2    Cattley, R.3    Goldsworthy, T.4
  • 10
    • 84883833956 scopus 로고
    • Cellular populations and mitotic activity in rat liver parenchyma during azo dye carcinogenesis
    • Daoust R., and Molnar F. Cellular populations and mitotic activity in rat liver parenchyma during azo dye carcinogenesis. Cancer Res. 24 (1964) 1898-1909
    • (1964) Cancer Res. , vol.24 , pp. 1898-1909
    • Daoust, R.1    Molnar, F.2
  • 11
    • 0015859585 scopus 로고
    • The ultra structure of the pineal ganglion in the ferret
    • David G.F.X., Herbert J., and Wright C.D.S. The ultra structure of the pineal ganglion in the ferret. J. Anat. 115 (1973) 79
    • (1973) J. Anat. , vol.115 , pp. 79
    • David, G.F.X.1    Herbert, J.2    Wright, C.D.S.3
  • 12
    • 0037069448 scopus 로고    scopus 로고
    • Antiepileptic drugs and apoptotic neurodegeneration in the developing brain
    • Dikranian K., Olney J.W., and Ikonomidou C. Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc. Natl. Acad. Sci. U. S. A. 99 23 (2002) 15089-15092
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , Issue.23 , pp. 15089-15092
    • Dikranian, K.1    Olney, J.W.2    Ikonomidou, C.3
  • 13
    • 0027969252 scopus 로고
    • Di (2-ethylhexyl) phthalate-induced changes in liver estrogen metabolism and hyperplasia
    • Eagon P.K., Chandar N., Epley M.J., Elm M.S., Brady E.P., and Rao K.N. Di (2-ethylhexyl) phthalate-induced changes in liver estrogen metabolism and hyperplasia. Int. J. Cancer 58 5 (1994) 736-743
    • (1994) Int. J. Cancer , vol.58 , Issue.5 , pp. 736-743
    • Eagon, P.K.1    Chandar, N.2    Epley, M.J.3    Elm, M.S.4    Brady, E.P.5    Rao, K.N.6
  • 17
    • 77957187759 scopus 로고
    • The relationship between uses of the wax tolerated dose and study sensitivity for detecting rodent carcinogenecity
    • Haseman J., and Lockhart A. The relationship between uses of the wax tolerated dose and study sensitivity for detecting rodent carcinogenecity. Fundam. Appl. Toxicol. 22 (1994) 382-391
    • (1994) Fundam. Appl. Toxicol. , vol.22 , pp. 382-391
    • Haseman, J.1    Lockhart, A.2
  • 18
    • 0025932848 scopus 로고
    • Liver tumor promoter phenobarbital: a biphasic modulator of hepatocyte proliferation
    • Butterwortyh B., Slaga T., Farland W., and McClain M. (Eds), Wiley-Liss, New York
    • Hirtle J., Meyer S., and Brockenbrough J. Liver tumor promoter phenobarbital: a biphasic modulator of hepatocyte proliferation. In: Butterwortyh B., Slaga T., Farland W., and McClain M. (Eds). Chemically Induced Cell Proliferation: Implications for Risk Assessment (1991), Wiley-Liss, New York 209-216
    • (1991) Chemically Induced Cell Proliferation: Implications for Risk Assessment , pp. 209-216
    • Hirtle, J.1    Meyer, S.2    Brockenbrough, J.3
  • 19
    • 0035851019 scopus 로고    scopus 로고
    • Gender differences in the potentiation of N-(3,5-dichlorophenyl) succinimide metabolite neprotoxicity by phenobarbital
    • Hong S.K., Anestis D.K., Valentovic M.A., Ball J.G., Brown P.I., and Rankin G.O. Gender differences in the potentiation of N-(3,5-dichlorophenyl) succinimide metabolite neprotoxicity by phenobarbital. J. Toxicol. Environ. Health 64 3 (2001) 241-256
    • (2001) J. Toxicol. Environ. Health , vol.64 , Issue.3 , pp. 241-256
    • Hong, S.K.1    Anestis, D.K.2    Valentovic, M.A.3    Ball, J.G.4    Brown, P.I.5    Rankin, G.O.6
  • 20
    • 34249701376 scopus 로고
    • Some aromatic azo compounds
    • International Agency for Research on Cancer (IARC)
    • International Agency for Research on Cancer (IARC). Some aromatic azo compounds. IARC Monogr. Eval. Carcinog. Risks Chem. Hum. 8 (1975) 357
    • (1975) IARC Monogr. Eval. Carcinog. Risks Chem. Hum. , vol.8 , pp. 357
  • 21
    • 0020196019 scopus 로고
    • Chemicals, industrial processes and industries associated with cancer in humans
    • International Agency for Research on Cancer (IARC), IARC, Lyon, France
    • International Agency for Research on Cancer (IARC). Chemicals, industrial processes and industries associated with cancer in humans. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans vol. 4 (1982), IARC, Lyon, France 292
    • (1982) IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Humans , vol.4 , pp. 292
  • 22
    • 0003595535 scopus 로고
    • On the evaluation of carcinogenic risk of chemicals to man
    • International Agency for Research on Cancer (IARC)
    • International Agency for Research on Cancer (IARC). On the evaluation of carcinogenic risk of chemicals to man. Group 2B 7 (1987) 440
    • (1987) Group 2B , vol.7 , pp. 440
  • 23
    • 34249707992 scopus 로고    scopus 로고
    • Summaries and evaluations, phenobarbital and its sodium salt
    • International Agency for Research on Cancer (IARC)
    • International Agency for Research on Cancer (IARC). Summaries and evaluations, phenobarbital and its sodium salt. Group 2B 79 (2001) 161-162
    • (2001) Group 2B , vol.79 , pp. 161-162
  • 25
    • 0016665355 scopus 로고
    • Cell proliferation and subcellular localization of alkaline phosphatase activity in rat liver parenchyma during azo dye carcinogenesis
    • Karasaki S. Cell proliferation and subcellular localization of alkaline phosphatase activity in rat liver parenchyma during azo dye carcinogenesis. Cancer Res. 35 (1975) 482-491
    • (1975) Cancer Res. , vol.35 , pp. 482-491
    • Karasaki, S.1
  • 26
    • 0042889217 scopus 로고    scopus 로고
    • Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression
    • Kinoshita A., Wanibuchi H., Wei K.M., Shen J., Imaoka S., Funae Y., and Fukushima S. Phenobarbital at low dose exerts hormesis in rat hepatocarcinogenesis by reducing oxidative DNA damage, altering cell proliferation, apoptosis and gene expression. Carcinogenesis 24 8 (2003) 1389-1399
    • (2003) Carcinogenesis , vol.24 , Issue.8 , pp. 1389-1399
    • Kinoshita, A.1    Wanibuchi, H.2    Wei, K.M.3    Shen, J.4    Imaoka, S.5    Funae, Y.6    Fukushima, S.7
  • 27
    • 0017373204 scopus 로고
    • Enhancement of azo-dye hepatocarcinogenesis with dietary phenobarbital in rats
    • Kitagawa T., and Sugano H. Enhancement of azo-dye hepatocarcinogenesis with dietary phenobarbital in rats. Gann 68 (1977) 255-256
    • (1977) Gann , vol.68 , pp. 255-256
    • Kitagawa, T.1    Sugano, H.2
  • 28
    • 0018117024 scopus 로고
    • Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine
    • Kitagawa T., and Sugano H. Enhancing effect of phenobarbital on the development of enzyme-altered islands and hepatocellular carcinomas initiated by 3'-methyl-4-(dimethylamino) azobenzene or diethylnitrosamine. Gann 69 5 (1978) 679-687
    • (1978) Gann , vol.69 , Issue.5 , pp. 679-687
    • Kitagawa, T.1    Sugano, H.2
  • 29
    • 0018346377 scopus 로고
    • Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat
    • Kitagawa T., Pitot H.C., Miller E.C., and Miller J.A. Promotion by dietary phenobarbital of hepatocarcinogenesis by 2-methyl-N,N-dimethyl-4-aminoazobenzene in the rat. Cancer Res. 39 1 (1979) 112-115
    • (1979) Cancer Res. , vol.39 , Issue.1 , pp. 112-115
    • Kitagawa, T.1    Pitot, H.C.2    Miller, E.C.3    Miller, J.A.4
  • 30
    • 0021735884 scopus 로고
    • Dose-response studies on promoting and anti-carcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis
    • Kitagawa T., Hino O., Nomura K., and Sugano H. Dose-response studies on promoting and anti-carcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis. Carcinogenesis 5 (1984) 1653-1656
    • (1984) Carcinogenesis , vol.5 , pp. 1653-1656
    • Kitagawa, T.1    Hino, O.2    Nomura, K.3    Sugano, H.4
  • 31
    • 0030005597 scopus 로고    scopus 로고
    • Dose dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: effects on DNA synthesis and apoptosis
    • Kolaja K., Stevensen D., Walborg E., and Klaunig J. Dose dependence of phenobarbital promotion of preneoplastic hepatic lesions in F344 rats and B6C3F1 mice: effects on DNA synthesis and apoptosis. Carcinogenesis 17 (1996) 947-954
    • (1996) Carcinogenesis , vol.17 , pp. 947-954
    • Kolaja, K.1    Stevensen, D.2    Walborg, E.3    Klaunig, J.4
  • 33
    • 9644284289 scopus 로고    scopus 로고
    • Effects of trypan blue on cell viability and gene expression in human retinal pigment epithelial cells
    • Kwok A.K.H., Yeung C.K., Lai T.Y.Y., Chan K.P., and Pang C.P. Effects of trypan blue on cell viability and gene expression in human retinal pigment epithelial cells. Br. J. Ophthalmol. 88 (2004) 1590-1594
    • (2004) Br. J. Ophthalmol. , vol.88 , pp. 1590-1594
    • Kwok, A.K.H.1    Yeung, C.K.2    Lai, T.Y.Y.3    Chan, K.P.4    Pang, C.P.5
  • 34
    • 0034117990 scopus 로고    scopus 로고
    • Paradoxical effects of phenobarbital on mouse carcinogenesis
    • Lee G.H. Paradoxical effects of phenobarbital on mouse carcinogenesis. Toxicol. Pathol. 28 (2000) 215-225
    • (2000) Toxicol. Pathol. , vol.28 , pp. 215-225
    • Lee, G.H.1
  • 36
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation
    • Liotta L.A., Steeg P.S., and Stetler-Stevenson W.G. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 64 (1991) 327-336
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 38
    • 0026566852 scopus 로고
    • Threshold dose-dependence in phenobarbital promotion of rat hepatocarcinogenesis initiated by diethylnitrosamine
    • Maekawa A., Onodera H., Ogasawara H., Matsushima Y., Mitsomuri K., and Hayashi Y. Threshold dose-dependence in phenobarbital promotion of rat hepatocarcinogenesis initiated by diethylnitrosamine. Carcinogenesis 13 (1992) 501-503
    • (1992) Carcinogenesis , vol.13 , pp. 501-503
    • Maekawa, A.1    Onodera, H.2    Ogasawara, H.3    Matsushima, Y.4    Mitsomuri, K.5    Hayashi, Y.6
  • 39
    • 0025230509 scopus 로고
    • Metalloproteinases and their inhibitors in matrix remodeling (Review)
    • Matrisian L.M. Metalloproteinases and their inhibitors in matrix remodeling (Review). Trends Genet. 6 (1990) 121-125
    • (1990) Trends Genet. , vol.6 , pp. 121-125
    • Matrisian, L.M.1
  • 40
    • 0027299459 scopus 로고
    • Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation
    • Melnick R., and Huff J. Liver carcinogenesis is not a predicted outcome of chemically induced hepatocyte proliferation. Toxicol. Ind. Health 9 (1993) 415-438
    • (1993) Toxicol. Ind. Health , vol.9 , pp. 415-438
    • Melnick, R.1    Huff, J.2
  • 41
    • 0003435820 scopus 로고
    • Merck & Company, Inc., Rahway, NJ
    • Merck. The Merck Index. 10th ed. (1983), Merck & Company, Inc., Rahway, NJ
    • (1983) The Merck Index. 10th ed.
    • Merck1
  • 42
    • 34249697146 scopus 로고    scopus 로고
    • National Institute for Occupational Safety and Health, 2004. http://www.cde.gov/niosh/npotocca.html.
  • 43
    • 0023264925 scopus 로고
    • Chemical carcinogenesis: a review and analysis of the literature of selected chemicals and the establishment of the gene-tox carcinogen database: a report of the US. Environmental Protection Agency gen-tox program
    • Nesn S., Argus M., Bergman H., Chu K., Frith C., Helmes T., Mcgaughy R., Ray V., Slaga T.J., Tennant R., and Weisburger E. Chemical carcinogenesis: a review and analysis of the literature of selected chemicals and the establishment of the gene-tox carcinogen database: a report of the US. Environmental Protection Agency gen-tox program. Mutat. Res. 185 (1987) 1-195
    • (1987) Mutat. Res. , vol.185 , pp. 1-195
    • Nesn, S.1    Argus, M.2    Bergman, H.3    Chu, K.4    Frith, C.5    Helmes, T.6    Mcgaughy, R.7    Ray, V.8    Slaga, T.J.9    Tennant, R.10    Weisburger, E.11
  • 44
    • 33644988073 scopus 로고    scopus 로고
    • Hypoglycemia, the first presenting sign of hepatocellular carcinoma
    • Nikeghbalian S., Bananzadeh A., and Yarmohammadi H. Hypoglycemia, the first presenting sign of hepatocellular carcinoma. Saudi Med. J. 27 3 (2006) 378-387
    • (2006) Saudi Med. J. , vol.27 , Issue.3 , pp. 378-387
    • Nikeghbalian, S.1    Bananzadeh, A.2    Yarmohammadi, H.3
  • 45
    • 34249717962 scopus 로고    scopus 로고
    • NTP. Report on Carcinogens, 2005. Eleventh edition. Research Triangle Park, NC: National Toxicology Program. http://ntp.niehs.nih.gov/index.cfm?Objectid=32BA9724-F1F6-975E-7FCE50709CB4C932.
  • 46
    • 0013902563 scopus 로고
    • Studies on the hepatocyte in azo dye carcinogenesis. Indian
    • Palekar S.D., and Sirsat S.M. Studies on the hepatocyte in azo dye carcinogenesis. Indian. J. Exp. Biol. (1966) 473-478
    • (1966) J. Exp. Biol. , pp. 473-478
    • Palekar, S.D.1    Sirsat, S.M.2
  • 47
    • 33646191834 scopus 로고    scopus 로고
    • Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice
    • Pathak S., Das J.K., Biswas S.J., and Khuda-Bukhsh A.R. Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice. Mol. Cell. Biochem. 285 (2006) 121-131
    • (2006) Mol. Cell. Biochem. , vol.285 , pp. 121-131
    • Pathak, S.1    Das, J.K.2    Biswas, S.J.3    Khuda-Bukhsh, A.R.4
  • 48
    • 0018934033 scopus 로고
    • Effects of varying the dietary concentration of phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis
    • Peraino C., Staffeldt E.F., Haugen D.A., Lombard L.S., Stevens F.J., and Fry R.J.M. Effects of varying the dietary concentration of phenobarbital on its enhancement of 2-acetylaminofluorene-induced hepatic tumorigenesis. Cancer Res. 40 (1980) 3268-3273
    • (1980) Cancer Res. , vol.40 , pp. 3268-3273
    • Peraino, C.1    Staffeldt, E.F.2    Haugen, D.A.3    Lombard, L.S.4    Stevens, F.J.5    Fry, R.J.M.6
  • 49
    • 0023430918 scopus 로고
    • A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered hepatic foci
    • Pitot H.C., Goldsworthy T.L., Moran S., Kennan W., Glauert H.P., Maronpot R.R., and Campbell H.A. A method to quantitate the relative initiating and promoting potencies of hepatocarcinogenic agents in their dose-response relationships to altered hepatic foci. Carcinogenesis 8 (1987) 1491-1499
    • (1987) Carcinogenesis , vol.8 , pp. 1491-1499
    • Pitot, H.C.1    Goldsworthy, T.L.2    Moran, S.3    Kennan, W.4    Glauert, H.P.5    Maronpot, R.R.6    Campbell, H.A.7
  • 50
    • 0031658358 scopus 로고    scopus 로고
    • The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate
    • Plant N., Horley N., Dickins M., Hasmall S., Elcombe C., and Bell D. The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate. Carcinogenesis 19 (1998) 1521-1527
    • (1998) Carcinogenesis , vol.19 , pp. 1521-1527
    • Plant, N.1    Horley, N.2    Dickins, M.3    Hasmall, S.4    Elcombe, C.5    Bell, D.6
  • 52
    • 0028073883 scopus 로고
    • The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis
    • Ray J.M., and Stetler-Stevenson W.G. The role of matrix metalloproteases and their inhibitors in tumour invasion, metastasis and angiogenesis. Eur. Respir. J. 7 (1994) 2062-2072
    • (1994) Eur. Respir. J. , vol.7 , pp. 2062-2072
    • Ray, J.M.1    Stetler-Stevenson, W.G.2
  • 53
    • 0028067549 scopus 로고
    • Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction
    • Seltzer J.L., Lee A.Y., Akers K.T., Sudbeck B., Southon E.A., Wayner E.A., and Eisen A.Z. Activation of 72-kDa type IV collagenase/gelatinase by normal fibroblasts in collagen lattices is mediated by integrin receptors but is not related to lattice contraction. Exp. Cell Res. 213 (1994) 365-374
    • (1994) Exp. Cell Res. , vol.213 , pp. 365-374
    • Seltzer, J.L.1    Lee, A.Y.2    Akers, K.T.3    Sudbeck, B.4    Southon, E.A.5    Wayner, E.A.6    Eisen, A.Z.7
  • 55
    • 0035188727 scopus 로고    scopus 로고
    • How matrix metalloproteases regulate cell behaviour
    • Sternlicht M.D., and Werb Z. How matrix metalloproteases regulate cell behaviour. Annu. Rev. Cell Dev. Biol. 17 (2001) 463-516
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 463-516
    • Sternlicht, M.D.1    Werb, Z.2
  • 56
    • 33244480829 scopus 로고    scopus 로고
    • Hepatocellular carcinoma with persistent hypoglycemia: successful treatment with corticosteroid and frequent high carbohydrate intake
    • Thipaporn T., Bubpha P., and Varaphon V. Hepatocellular carcinoma with persistent hypoglycemia: successful treatment with corticosteroid and frequent high carbohydrate intake. J. Med. Assoc. Thailand 88 12 (2005) 1941-1946
    • (2005) J. Med. Assoc. Thailand , vol.88 , Issue.12 , pp. 1941-1946
    • Thipaporn, T.1    Bubpha, P.2    Varaphon, V.3
  • 59
    • 0018604170 scopus 로고
    • Effect of phenobarbital on induction of liver and lung tumors by dimethylnitrosamine in newborn mice
    • Uchida E., and Hirono I. Effect of phenobarbital on induction of liver and lung tumors by dimethylnitrosamine in newborn mice. Gann 70 (1979) 639-644
    • (1979) Gann , vol.70 , pp. 639-644
    • Uchida, E.1    Hirono, I.2
  • 60
    • 0019417544 scopus 로고
    • Effect of phenobarbital on the development of neoplastic lesions in the liver of cycasin-treated rats
    • Uchida E., and Hirono I. Effect of phenobarbital on the development of neoplastic lesions in the liver of cycasin-treated rats. J. Cancer Res. Clin. Oncol. 100 (1981) 231-238
    • (1981) J. Cancer Res. Clin. Oncol. , vol.100 , pp. 231-238
    • Uchida, E.1    Hirono, I.2
  • 61
    • 0034714202 scopus 로고    scopus 로고
    • TIMP-2 is required for efficient activation of pro MMP-2 in vivo
    • Wang Z., Juttermann R., and Soloway P.D. TIMP-2 is required for efficient activation of pro MMP-2 in vivo. J. Biol. Chem. 275 (2000) 26411-26415
    • (2000) J. Biol. Chem. , vol.275 , pp. 26411-26415
    • Wang, Z.1    Juttermann, R.2    Soloway, P.D.3
  • 62
    • 0018406229 scopus 로고
    • Anticonvulsant drugs and cancer, a cohort study in patients with severe epilepsy
    • White S.J., McLean A.E.M., and Howland C. Anticonvulsant drugs and cancer, a cohort study in patients with severe epilepsy. Lancet ii (1979) 458-461
    • (1979) Lancet , vol.ii , pp. 458-461
    • White, S.J.1    McLean, A.E.M.2    Howland, C.3
  • 63
    • 0025847582 scopus 로고
    • Matrix metalloproteinases and their inhibitors in connective tissue remodeling
    • Woessner Jr. J.F. Matrix metalloproteinases and their inhibitors in connective tissue remodeling. FASEB J. 5 (1991) 2145-2154
    • (1991) FASEB J. , vol.5 , pp. 2145-2154
    • Woessner Jr., J.F.1
  • 64
    • 0025788510 scopus 로고
    • Roles of ovaries and testes in hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene
    • Yamamoto R., Iishi H., Tatsuta M., Tsuji M., and Terada N. Roles of ovaries and testes in hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene. Int. J. Cancer 49 1 (1991) 83-88
    • (1991) Int. J. Cancer , vol.49 , Issue.1 , pp. 83-88
    • Yamamoto, R.1    Iishi, H.2    Tatsuta, M.3    Tsuji, M.4    Terada, N.5
  • 65
    • 0027380018 scopus 로고
    • Suppressive effect of estrogen on hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene
    • Yamamoto R., Iishi H., Tatsuta M., Tsuji M., and Terada N. Suppressive effect of estrogen on hepatocellular tumorigenesis induced in mice by 3′-methyl-4-dimethylaminoazobenzene. Exp. Toxicol. Pathol. 45 5-6 (1993) 325-328
    • (1993) Exp. Toxicol. Pathol. , vol.45 , Issue.5-6 , pp. 325-328
    • Yamamoto, R.1    Iishi, H.2    Tatsuta, M.3    Tsuji, M.4    Terada, N.5
  • 66
    • 33644975940 scopus 로고    scopus 로고
    • Hypoglycaemia in hepatocellular carcinoma: a review
    • Yeung R.T. Hypoglycaemia in hepatocellular carcinoma: a review. Hong Kong Med. J. 3 3 (1997) 297-301
    • (1997) Hong Kong Med. J. , vol.3 , Issue.3 , pp. 297-301
    • Yeung, R.T.1
  • 67
    • 4143068028 scopus 로고    scopus 로고
    • The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo
    • Zhang K., and Chow P.K.H. The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo. Clin. Cancer Res. 10 (2004) 5226-5232
    • (2004) Clin. Cancer Res. , vol.10 , pp. 5226-5232
    • Zhang, K.1    Chow, P.K.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.