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Volumn 35, Issue 6, 2007, Pages 886-902

Statistical analysis of metabolic pathways of brain metabolism at steady state

Author keywords

Bayesian statistics; Brain; Flux balance; Markov Chain Monte Carlo; Metabolism; Multicompartment model; Neural activity

Indexed keywords

BAYESIAN NETWORKS; BLOOD; MARKOV PROCESSES; METABOLISM; MONTE CARLO METHODS; NEURAL NETWORKS;

EID: 34249735789     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-007-9270-5     Document Type: Conference Paper
Times cited : (24)

References (28)
  • 1
    • 27544470356 scopus 로고    scopus 로고
    • Interaction between astrocytes and neurons studied using a mathematical model of compartmentalized energy metabolism
    • Aubert, A., and R. Costalat. Interaction between astrocytes and neurons studied using a mathematical model of compartmentalized energy metabolism. J. Cereb. Blood Flow Metab. 25:1476-1490, 2005.
    • (2005) J. Cereb. Blood Flow Metab , vol.25 , pp. 1476-1490
    • Aubert, A.1    Costalat, R.2
  • 2
    • 0030804853 scopus 로고    scopus 로고
    • Flux analysis of underdetermined metabolic networks: The quest for the missing constraints
    • Bonarius, H. P. J., G. Schmid, and J. Tramper. Flux analysis of underdetermined metabolic networks: the quest for the missing constraints. Trends Biotechnol. 15:308-314, 1997.
    • (1997) Trends Biotechnol , vol.15 , pp. 308-314
    • Bonarius, H.P.J.1    Schmid, G.2    Tramper, J.3
  • 3
    • 34249661485 scopus 로고    scopus 로고
    • Large scale statistical parameter estimation in complex systems with application to metabolic models
    • Calvetti, D., and E. Somersalo. Large scale statistical parameter estimation in complex systems with application to metabolic models. Multiscale Model. Simul. 5(4): 1333-1366, 2006.
    • (2006) Multiscale Model. Simul , vol.5 , Issue.4 , pp. 1333-1366
    • Calvetti, D.1    Somersalo, E.2
  • 4
    • 34249695271 scopus 로고    scopus 로고
    • Bayesian stationary state flux balance analysis for a skeletal muscle metabolic model
    • Calvetti, D., J. Heino, E. Somersalo, and K. Tunyan. Bayesian stationary state flux balance analysis for a skeletal muscle metabolic model. Inverse Problems and Imaging 1(2):247-263, 2007.
    • (2007) Inverse Problems and Imaging , vol.1 , Issue.2 , pp. 247-263
    • Calvetti, D.1    Heino, J.2    Somersalo, E.3    Tunyan, K.4
  • 5
    • 0035478762 scopus 로고    scopus 로고
    • Do active cerebral neurons really use lactate rather than glucose?
    • Chih, C.-P., P. Lipton, and E. L. Roberts Jr. Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci. 24(10):573-578, 2001.
    • (2001) Trends Neurosci , vol.24 , Issue.10 , pp. 573-578
    • Chih, C.-P.1    Lipton, P.2    Roberts Jr., E.L.3
  • 7
    • 0036137183 scopus 로고    scopus 로고
    • Oxidative and nonoxidative metabolism of excited neurons and astrocytes
    • Gjedde, A., S. Marrett, and M. Vafaee. Oxidative and nonoxidative metabolism of excited neurons and astrocytes. J. Cereb. Blood Flow Metab. 22:1-14, 2002.
    • (2002) J. Cereb. Blood Flow Metab , vol.22 , pp. 1-14
    • Gjedde, A.1    Marrett, S.2    Vafaee, M.3
  • 8
    • 0034965524 scopus 로고    scopus 로고
    • Carboxylation and anaplerosys in neurons and glia
    • Hassel, B. Carboxylation and anaplerosys in neurons and glia. Mol. Newobiol. 22(1-3):21-40, 2001.
    • (2001) Mol. Newobiol , vol.22 , Issue.1-3 , pp. 21-40
    • Hassel, B.1
  • 12
    • 0021957477 scopus 로고
    • Regional comparisons of brain glucose influx
    • LaManna, J. C., and S. Harik. Regional comparisons of brain glucose influx. Brain Res. 326(2):299-305, 1985.
    • (1985) Brain Res , vol.326 , Issue.2 , pp. 299-305
    • LaManna, J.C.1    Harik, S.2
  • 14
    • 34249675640 scopus 로고    scopus 로고
    • Liu, J. S. Monte Carlo Strategies in Scientific Computing. New York: Springer Verlag, 2003.
    • Liu, J. S. Monte Carlo Strategies in Scientific Computing. New York: Springer Verlag, 2003.
  • 15
    • 0002335520 scopus 로고
    • The relationships between substrates and enzymes of glycolysis in brain
    • Lowry, O. H., and J. V. Passonneau. The relationships between substrates and enzymes of glycolysis in brain. J. Biol. Chem. 239(1):31-42, 1964.
    • (1964) J. Biol. Chem , vol.239 , Issue.1 , pp. 31-42
    • Lowry, O.H.1    Passonneau, J.V.2
  • 16
    • 0002809955 scopus 로고
    • Effects of ischemia on known substrates and cofactors of the glycolitic pathway in brain
    • Lowry, O. H., J. V. Passonneau, F. X. Hasselberger, and D. W. Schulz. Effects of ischemia on known substrates and cofactors of the glycolitic pathway in brain. J. Biol. Chem. 239(1):18-30, 1964.
    • (1964) J. Biol. Chem , vol.239 , Issue.1 , pp. 18-30
    • Lowry, O.H.1    Passonneau, J.V.2    Hasselberger, F.X.3    Schulz, D.W.4
  • 19
    • 17144475351 scopus 로고    scopus 로고
    • The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo
    • Patel, A. B., R. A. de Graaf, G. F. Mason, D. L. Rothman, R.G. Shulman, and K. L. Behar. The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo. Proc. Natl. Acad. Sci. U.S.A. 102(15):5588-5593, 2005.
    • (2005) Proc. Natl. Acad. Sci. U.S.A , vol.102 , Issue.15 , pp. 5588-5593
    • Patel, A.B.1    de Graaf, R.A.2    Mason, G.F.3    Rothman, D.L.4    Shulman, R.G.5    Behar, K.L.6
  • 20
    • 1642457265 scopus 로고    scopus 로고
    • Neuroenergetics: Calling upon astrocytes to satisfy hungry neurons
    • Pellerin, L., and P. J. Magistretti. Neuroenergetics: calling upon astrocytes to satisfy hungry neurons. Neuroscientist 10(1):53-62, 2004.
    • (2004) Neuroscientist , vol.10 , Issue.1 , pp. 53-62
    • Pellerin, L.1    Magistretti, P.J.2
  • 22
    • 0034615791 scopus 로고    scopus 로고
    • Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathwayoriented perspective
    • Schilling, C. H., D. Letscher, and B. O. Palsson. Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathwayoriented perspective. J. Theor. Biol. 203(3):229-248, 2000.
    • (2000) J. Theor. Biol , vol.203 , Issue.3 , pp. 229-248
    • Schilling, C.H.1    Letscher, D.2    Palsson, B.O.3
  • 23
    • 0032516028 scopus 로고    scopus 로고
    • The underlying pathway structure of biochemical reaction networks
    • Schilling, C. H., and B. O. Palsson. The underlying pathway structure of biochemical reaction networks. Proc. Natl. Acad. Sci. U.S.A. 95(8):4193-4198, 1998.
    • (1998) Proc. Natl. Acad. Sci. U.S.A , vol.95 , Issue.8 , pp. 4193-4198
    • Schilling, C.H.1    Palsson, B.O.2
  • 24
    • 3242737585 scopus 로고    scopus 로고
    • Energetics basis of brain activity: Implications for neuroimaging
    • Shulman, R. G., D. L. Rothman, K. L. Behar, and F. Hyder. Energetics basis of brain activity: Implications for neuroimaging. Trends Neurosci. 27(8):489-495, 2004.
    • (2004) Trends Neurosci , vol.27 , Issue.8 , pp. 489-495
    • Shulman, R.G.1    Rothman, D.L.2    Behar, K.L.3    Hyder, F.4
  • 26
    • 0028108519 scopus 로고    scopus 로고
    • Metabolic flux balancing; basic concepts, scientific and practical use
    • Varma, A., and B. O. Palsson. Metabolic flux balancing; basic concepts, scientific and practical use. Bio/Technology 12:994-998, 1998.
    • (1998) Bio/Technology , vol.12 , pp. 994-998
    • Varma, A.1    Palsson, B.O.2
  • 27
    • 0014082605 scopus 로고
    • The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver
    • Williamson, D. H., P. Lund, and H. A. Krebs. The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. Biochem. J. 103(2):514-527, 1967.
    • (1967) Biochem. J , vol.103 , Issue.2 , pp. 514-527
    • Williamson, D.H.1    Lund, P.2    Krebs, H.A.3
  • 28
    • 18044377998 scopus 로고    scopus 로고
    • Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia
    • Zhou, L., J. E. Salem, G. M. Saidel, W. C. Stanley, and M. E. Cabrera. Mechanistic model of cardiac energy metabolism predicts localization of glycolysis to cytosolic subdomain during ischemia. Am. J. Physiol. Heart Circ. Physiol. 288:2400-2411, 2005.
    • (2005) Am. J. Physiol. Heart Circ. Physiol , vol.288 , pp. 2400-2411
    • Zhou, L.1    Salem, J.E.2    Saidel, G.M.3    Stanley, W.C.4    Cabrera, M.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.