Object-oriented Bayesian networks for complex forensic DNA profiling problems

Forensic Science International

Volumn 169, Issue 2-3, 2007, Pages 195-205

  Dawid, A P ^a   Mortera, J ^b   Vicard, P ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROMA TRE UNIVERSITY   (Italy)

Author keywords

Bayesian network; DNA profile; Missed allele; Mutation; Null allele; Object oriented; Paternity testing; Silent allele

Indexed keywords

ALLELE; ARTICLE; BAYES THEOREM; DNA FINGERPRINTING; FORENSIC SCIENCE; HUMAN; MUTATION; OFFENDER; PATERNITY TEST; PRIORITY JOURNAL;

EID: 34249729995     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2006.08.028     Document Type: Article

References (26)

1. Evett I.W., and Weir B.S. Interpreting DNA Evidence (1998), Sinauer, Sunderland, MA
2. Morling N., Allen R.W., Carracedo A., Geada H., Guidet F., Hallenberg C., Martin W., Mayr W.R., Olaisen B., Pascali V.L., and Schneider P.M. Paternity Testing Commission of the International Society of Forensic Genetics: recommendations on genetic investigations in paternity cases. Forensic Sci. Int. 129 (2002) 148-157
3. Dawid A.P., Mortera J., Pascali V.L., and van Boxel D.W. Probabilistic expert systems for forensic inference from genetic markers. Scand. J. Stat. 29 (2002) 577-595
4. Mortera J. Analysis of DNA mixtures using Bayesian networks. In: Green P.J., Hjort N.L., and Richardson S. (Eds). Highly Structured Stochastic Systems (2003), Oxford University Press 39-44 Ch. 1B
5. Mortera J., Dawid A.P., and Lauritzen S.L. Probabilistic expert systems for DNA mixture profiling. Theor. Popul. Biol. 63 (2003) 191-205
6. Dawid A.P. An object-oriented Bayesian network for estimating mutation rates. In: Bishop C.M., and Frey B.J. (Eds). Proceedings of the Ninth International Workshop on Artificial Intelligence and Statistics. Key West, FL, January 3-6 (2003). http://tinyurl.com/39bmh
7. Cowell R.G., Dawid A.P., Lauritzen S.L., and Spiegelhalter D.J. Probabilistic Networks and Expert Systems (1999), Springer, New York
8. Taroni F., Aitken C., Garbolino P., and Biedermann A. Bayesian Networks and Probabilistic Inference in Forensic Science, Statistics in Practice (2006), John Wiley and Sons, Chichester
9. Laskey K.B., and Mahoney S.M. Network fragments: representing knowledge for constructing probabilistic models. In: Geiger D., and Shenoy P. (Eds). Proceedings of the 13th Annual Conference on Uncertainty in Artificial Intelligence. Morgan Kaufmann Publishers, San Francisco (1997) 334-341
10. Koller D., and Pfeffer A. Object-oriented Bayesian networks. In: Geiger D., and Shenoy P. (Eds). Proceedings of the 13th Annual Conference on Uncertainty in Artificial Intelligence. Morgan Kaufmann Publishers, San Francisco (1997) 302-313
11. Bangsø O., and Wuillemin P.H. Object-oriented Bayesian networks: a framework for top-down specification of large Bayesian networks with repetitive structures, Technical Report (2000), Hewlett-Packard Laboratory for Normative Systems, Aalborg University
12. Dawid A.P., Mortera J., and Vicard P. Representing and solving complex DNA identification cases using Bayesian networks. In: Amorim A., Corte-Real F., and Morling N. (Eds). Progress in Forensic Genetics 11, vol. 1288 of International Congress Series. Elsevier, Amsterdam (2006) 484-491
13. Dawid A.P., Mortera J., and Vicard P. Object-oriented Bayesian networks for complex forensic DNA profiling problems, Research Report 256 (2005), Department of Statistical Science, University College London. http://www.ucl.ac.uk/Stats/research/abs05.html#256
14. Essen-Möller E. Die Beweiskraft der Ähnlichkeit im Vaterschaftsnachweis. Theoretische Grundlagen. Mitteilungen der Anthropologischen Gesellschaft 68 (1938) 9-53
15. Dawid A.P., Mortera J., and Pascali V.L. Non-fatherhood or mutation? A probabilistic approach to parental exclusion in paternity testing. Forensic Sci. Int. 124 (2001) 55-61
16. Vicard P., and Dawid A.P. A statistical treatment of biases affecting the estimation of mutation rates. Mut. Res. 547 (2004) 19-33
17. Gill P., Whitaker J., Flaxman C., Brown N., and Buckleton J. An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA. Forensic Sci. Int. 112 (2000) 17-40
18. Brenner C.H. Symbolic kinship program. Genetics 145 (1997) 535-542
19. ® SGM Plus™ kit. Forensic Sci. Int. 139 (2004) 255-259
20. Leopoldino A.M., and Pena S.D.J. The mutational spectrum of human autosomal tetranucleotide microsatellites. Hum. Mut. 21 (2002) 71-79
21. S. Merigioli, Object-oriented Bayesian networks for DNA paternity test applications, Master's Thesis, Department of Statistical Science, University College London, 2006.
22. Dawid A.P., and Evett I.W. Using a graphical method to assist the evaluation of complicated patterns of evidence. J. Forensic Sci. 42 (1997) 226-231
23. Dajda T., and Jung M. LR-calculation of any kinship situation using a new graphical interface: generate two or more hypotheses, draw the family trees and assign the DNA-profiles to person symbols. In: Amorim A., Corte-Real F., and Morling N. (Eds). Progress in Forensic Genetics 11, vol. 1288 of International Congress Series. Elsevier, Amsterdam (2006) 474-476
24. Cowell R.G. FINEX: a probabilistic expert system for forensic identification. Forensic Sci. Int. 134 (2003) 196-206
25. ® SGM Plus™ multiplex system for both standard and low copy number (LCN) STR DNA analysis. Forensic Sci. Int. 123 (2001) 215-223
26. Cowell R.G., Lauritzen S.L., and Mortera J. Identification and separation of DNA mixtures using peak area information. Forensic Sci. Int. 166 (2007) 28-34