Genomic Biomarkers and Heart Transplantation

Heart Failure Clinics

Volumn 3, Issue 1, 2007, Pages 83-86

  Mehra, Mandeep R ^a   Uber, Patricia A ^a  

^a UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PREDNISONE;

BLOOD TRANSFUSION; CARDIAC GRAFT REJECTION; DNA STRUCTURE; GENE EXPRESSION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; T LYMPHOCYTE ACTIVATION;

BIOLOGICAL MARKERS; BIOPSY; ENDOCARDIUM; GENE EXPRESSION PROFILING; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; MULTIGENE FAMILY; MYOCARDIUM; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; ROC CURVE;

EID: 34249729455     PISSN: 15517136     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hfc.2007.03.004     Document Type: Review

References (18)

1. Marboe C.C., Billingham M., Eisen H., et al. Nodular endocardial infiltrates (quilty lesions) cause significant variability in diagnosis of ISHLT grade 2 and 3A rejection in cardiac allograft recipients. J Heart Lung Transplant 24 Suppl 7 (2005) S219-S226
2. Stewart S., Winters G.L., Fishbein M.C., et al. Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection. J Heart Lung Transplant 24 11 (2005) 1710-1720
3. Awad M.R., Webber S., Boyle G., et al. The effect of cytokine gene polymorphisms on pediatric heart allograft outcome. J Heart Lung Transplant 20 6 (2001) 625-630
4. Abdallah A.N., Cucchi-Mouillot P., Biteau N., et al. Analysis of the polymorphism of the tumour necrosis factor (TNF) gene and promoter and of circulating TNF-alpha levels in heart-transplant patients suffering or not suffering from severe rejection. Eur J Immunogenet 26 4 (1999) 249-255
5. Densem C.G., Hutchinson I.V., Yonan N., et al. Influence of tumor necrosis factor-alpha gene-308 polymorphism on the development of coronary vasculopathy after cardiac transplantation. J Heart Lung Transplant 20 12 (2001) 1265-1273
6. Pethig K., Heublein B., Hoffmann A., et al. ACE-gene polymorphism is associated with the development of allograft vascular disease in heart transplant recipients. J Heart Lung Transplant 19 12 (2000) 1175-1182
7. Baan C.C., Balk A.H., Holweg C.T., et al. Renal failure after clinical heart transplantation is associated with the TGF-beta 1 codon 10 gene polymorphism. J Heart Lung Transplant 19 9 (2000) 866-872
8. Zheng H., Webber S., Zeevi A., et al. Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. Am J Transplant 3 4 (2003) 477-483
9. Zheng H.X., Webber S.A., Zeevi A., et al. The impact of pharmacogenomic factors on steroid dependency in pediatric heart transplant patients using logistic regression analysis. Pediatr Transplant 8 6 (2004) 551-557
10. Shulzhenko N., Morgun A., Zheng X.X., et al. Intragraft activation of genes encoding cytotoxic T lymphocyte effector molecules precedes the histological evidence of rejection in human cardiac transplantation. Transplantation 72 10 (2001) 1705-1708
11. de Groot-Kruseman H.A., Mol W.M., Niesters H.G., et al. Differential intragraft cytokine messenger RNA profiles during rejection and repair of clinical heart transplants. A longitudinal study. Transpl Int 16 1 (2003) 9-14
12. Fahmy N.M., Yamani M.H., Starling R.C., et al. Chemokine and chemokine receptor gene expression indicates acute rejection of human cardiac transplants. Transplantation 75 1 (2003) 72-78
13. Horwitz P.A., Tsai E.J., Putt M.E., et al. Detection of cardiac allograft rejection and response to immunosuppressive therapy with peripheral blood gene expression. Circulation 110 25 (2004) 3815-3821
14. Morgun A., Shulzhenko N., Rampim G.F., et al. Blood and intragraft CD27 gene expression in cardiac transplant recipients. Clin Immunol 107 1 (2003) 60-64
15. Schoels M., Dengler T.J., Richter R., et al. Detection of cardiac allograft rejection by real-time PCR analysis of circulating mononuclear cells. Clin Transplant 18 5 (2004) 513-517
16. Deng M.C., Eisen H.J., Mehra M.R., et al., CARGO investigators. Noninvasive discrimination of rejection in cardiac allograft recipients using gene expression profiling. Am J Transplant 6 1 (2006) 150-160
17. Mehra M., Kobashigawa J., Deng M.C., et al. The role of IL1R2 and FLT3 gene expression in cardiac allograft rejection: a precise measure of corticosteroid effect?. Circulation 114 18 (2006) II3341
18. Starling R.C., Pham M., Valantine H., et al., Working Group on Molecular Testing in Cardiac Transplantation. Molecular testing in the management of cardiac transplant recipients: initial clinical experience. J Heart Lung Transplant 25 12 (2006) 1389-1395