Intragraft activation of genes encoding cytotoxic t lymphocyte effector molecules precedes the histological evidence of rejection in human cardiac transplantation

Transplantation

Volumn 72, Issue 10, 2001, Pages 1705-1708

  Shulzhenko, Natalia ^a   Morgun, Andrey ^a   Zheng, Xin X ^b   Diniz, Rosiane V Z ^a   Almeida, Dirceu R ^a   Ma, Naili ^b   Strom, Terry B ^b   Gerbase DeLima, Maria ^a,c  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c NONE   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; GRANZYME B; MESSENGER RNA; PERFORIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE ACTIVATION; GENE EXPRESSION; GENETIC TRANSCRIPTION; GRAFT REJECTION; HEART GRAFT; HEART MUSCLE BIOPSY; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0035960640     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200111270-00025     Document Type: Article

References (10)

1. The Registry of the International Society for Heart and Lung Transplantation: Sixteenth official report-1999
2. The use and misuse of immunologic monitoring after transplantation: Approaches that have proved useful
3. Endomyocardial biopsies: The potential margin of error
4. Correlation of endomyocardial biopsy findings with autopsy findings in human cardiac allografts
5. Molecular executors of cell death: Differential intrarenal expression of Fas ligand, Fas, granzyme B, and perforin during acute or chronic rejection of human renal allografts
6. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation
7. The relationship of granzyme A and perforin expression to cardiac allograft rejection and dysfunction
8. Increased intragraft expression of immune activation genes in rejecting human cardiac allografts
9. Granzyme B and perforin can be used as predictive markers in heart transplantation
10. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection: Heart rejection study group