Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness

Journal of Biological Chemistry

Volumn 282, Issue 16, 2007, Pages 11858-11865

  Fijolek, Artur ^a   Hofer, Anders ^a   Thelander, Lars ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; DISEASES; MICROORGANISMS; MOLECULAR BIOLOGY;

RHODESIENSE; SLEEPING SICKNESS; SYNTHETASE; TRYPANOSOME CTP SYNTHETASE;

ENZYMES;

ACIVICIN; CYTIDINE TRIPHOSPHATE SYNTHASE; ANTITRYPANOSOMAL AGENT; CYTIDINE; CYTOSINE; ENZYME INHIBITOR; LIGASE;

AFRICAN TRYPANOSOMIASIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG UPTAKE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN TARGETING; TRYPANOSOMA BRUCEI; WEIGHT REDUCTION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; DOSE RESPONSE; ENZYMOLOGY; HUMAN; KINETICS; TRYPANOSOMA;

MAMMALIA; MUS; TRYPANOSOMA BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE;

ANIMALS; CARBON-NITROGEN LIGASES; CYTIDINE; CYTOSINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; KINETICS; MALE; MICE; MICE, INBRED C57BL; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI; TRYPANOSOMA BRUCEI GAMBIENSE; TRYPANOSOMIASIS, AFRICAN;

EID: 34249692495     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611580200     Document Type: Article

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