Mechanism of saikosaponin-d in the regulation of rat mesangial cell proliferation and synthesis of extracellular matrix proteins

Biochemistry and Cell Biology

Volumn 85, Issue 2, 2007, Pages 169-174

  Zu, Ning ^a   Li, Ping ^a   Li, Ning ^a   Choy, Patrick ^b   Gong, Yuewen ^b  

^a CHINA JAPAN FRIENDSHIP HOSPITAL   (China)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Extracellular matrix; Glomerulosclerosis; Kidney fibrosis; Saikosaponin d; Transforming growth factor beta1

Indexed keywords

BIOASSAY; BIOLOGICAL ORGANS; CELL PROLIFERATION; CYTOTOXICITY; PROTEINS; RATS; SYNTHESIS (CHEMICAL);

EXTRACELLULAR MATRIX; GLOMERULOSCLEROSIS; KIDNEY FIBROSIS; SAIKOSAPONIN-D; TRANSFORMING GROWTH FACTOR BETA1;

DISEASES;

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; COLLAGEN TYPE 4; CYCLIN DEPENDENT KINASE 4; FIBRONECTIN; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; PROTEIN C FOS; PROTEIN C JUN; SAIKOSAPONIN D; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; CELL DEATH; CELL ISOLATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ASSAY; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; MALE; MESANGIUM CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CELL PROLIFERATION; CELLS, CULTURED; CHRONIC DISEASE; COLLAGEN TYPE IV; CYCLIN-DEPENDENT KINASE 4; DOWN-REGULATION; FEMALE; FIBRINOGEN; GLOMERULOSCLEROSIS, FOCAL SEGMENTAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MESANGIAL CELLS; OLEANOLIC ACID; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SAPONINS; SIGNAL TRANSDUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 34249689123     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/O07-002     Document Type: Conference Paper

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