Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of DMXAA in human and mouse plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 217-222

  Zhang, Xiaosong ^a,b   Zhao, Ming ^b   Rudek, Michelle A ^b   He, Ping ^b   Vogelstein, Bert ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

DMXAA; LC MS MS; Pharmacokinetics

Indexed keywords

ACETONITRILE; CARBOXYLIC ACIDS; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); PRECIPITATION (CHEMICAL); PROTEINS;

AMMONIUM ACETATE; INTERNAL STANDARD; ISOPROPOXY; PROTEIN PRECIPITATION;

LIQUID CHROMATOGRAPHY;

5,6 DIMETHYLXANTHENONE 4 ACETIC ACID; 6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; ACETONITRILE; AMMONIUM ACETATE; FORMIC ACID;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG STRUCTURE; ELECTROSPRAY; FREEZE THAWING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; STANDARDIZATION; SUSTAINED RELEASE PREPARATION; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTINEOPLASTIC AGENTS; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; XANTHONES;

MUS;

EID: 34249666188     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.01.018     Document Type: Article

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