A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology

Brain

Volumn 130, Issue 5, 2007, Pages 1360-1374

  Leverenz, J B ^a,c,d   Yu, C E ^b   Montine, T J ^d   Steinbart, E ^b,d   Bekris, L M ^b   Zabetian, C ^b,d   Kwong, L K ^e   Lee, V M Y ^e   Schellenberg, G D ^a,b,d   Bird, T D ^b,d,f  

^a Mental Illness   (United States)

^b Puget Sound Health Care System   (United States)

^c Education   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f S 182 GRECC   (United States)

Author keywords

Alpha synuclein; Frontotemporal dementia; Neurogenetics; Progranulin; Tau

Indexed keywords

ALPHA SYNUCLEIN; BRAIN PROTEIN; MESSENGER RNA; PROGRANULIN; PROTEIN ANTIBODY; TAU PROTEIN; TDP43 PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; GRN PROTEIN, HUMAN; MAPT PROTEIN, HUMAN; PROTEIN TDP 43; PROTEIN TDP-43; SIGNAL PEPTIDE; UBIQUITIN;

ADULT; AGED; ARTICLE; AUTOPSY; BEHAVIOR CHANGE; CELL INCLUSION; CELL LOSS; CELL NUCLEUS; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; CORPUS STRIATUM; CYTOPLASM; DEMENTIA; DISEASE DURATION; DISEASE SEVERITY; EXON; FAMILY STUDY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE CONSTRUCT; GENE MUTATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LANGUAGE DISABILITY; MALE; MICROSCOPY; MOLECULAR GENETICS; MUTATIONAL ANALYSIS; NEOCORTEX; NERVE CELL; NEURITE; NEUROPATHOLOGY; ONSET AGE; PARKINSONISM; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN LOCALIZATION; RNA SPLICING; STAINING; SUBSTANTIA NIGRA; BRAIN; CASE CONTROL STUDY; CHEMISTRY; DNA SEQUENCE; GENETICS; GENOTYPE; METABOLISM; METHODOLOGY; MIDDLE AGED; MUTATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PEDIGREE; PICK PRESENILE DEMENTIA; WESTERN BLOTTING;

ADULT; AGE OF ONSET; AGED; ALPHA-SYNUCLEIN; BLOTTING, WESTERN; BRAIN; CASE-CONTROL STUDIES; CORPUS STRIATUM; DNA-BINDING PROTEINS; FEMALE; GENOTYPE; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MUTATION; NEOCORTEX; PEDIGREE; PICK DISEASE OF THE BRAIN; SEQUENCE ANALYSIS, DNA; SUBSTANTIA NIGRA; TAU PROTEINS; UBIQUITIN;

EID: 34249658365     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awm069     Document Type: Article

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