Pleofungins, novel inositol phosphorylceramide synthase inhibitors, from Phoma sp. SANK 13899: I. Taxonomy, fermentation, isolation, and biological activities

Journal of Antibiotics

Volumn 60, Issue 2, 2007, Pages 136-142

  Yano, Tatsuya ^a   Aoyagi, Azusa ^a   Kozuma, Shiho ^a   Kawamura, Yoko ^a   Tanaka, Isshin ^a   Suzuki, Yasuhiro ^a   Takamatsu, Yasuyuki ^a   Takatsu, Toshio ^a   Inukai, Masatoshi ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Anti fungal; Aspergillus fumigatus; Inositol phosphoryceramide synthase; Pleofungin; Sphingolipid

Indexed keywords

ANTIFUNGAL AGENT; AUREOBASIDIN A; ENZYME INHIBITOR; GALBONOLIDE A; INOSITOL PHOSPHORYLCERAMIDE SYNTHASE; PLEOFUNGIN A; PLEOFUNGIN B; PLEOFUNGIN C; PLEOFUNGIN D; SPHINGOSINE ACYLTRANSFERASE; UNCLASSIFIED DRUG; DEPSIPEPTIDE; GLYCOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL CERAMIDE PHOSPHOINOSITOL TRANSFERASE; PHOSPHATIDYLINOSITOL-CERAMIDE PHOSPHOINOSITOL TRANSFERASE; SPHINGOLIPID;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; DRUG ISOLATION; DRUG PURIFICATION; DRUG SYNTHESIS; ENZYME INHIBITION; FUNGUS; FUNGUS GROWTH; IC 50; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHOMA; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; ASCOMYCETES; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; SYNTHESIS;

ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; FILOBASIDIELLA NEOFORMANS; FUNGI; PHOMA; SACCHAROMYCES CEREVISIAE;

ANTIBIOTICS, ANTIFUNGAL; ASCOMYCOTA; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CRYPTOCOCCUS NEOFORMANS; DEPSIPEPTIDES; ENZYME INHIBITORS; FERMENTATION; HEXOSYLTRANSFERASES; MICROBIAL SENSITIVITY TESTS; SACCHAROMYCES CEREVISIAE; SPHINGOLIPIDS;

EID: 34249653488     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2007.13     Document Type: Article

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