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Volumn 39, Issue 6, 2007, Pages 1087-1092

Exposure to 56 Fe irradiation accelerates normal brain aging and produces deficits in spatial learning and memory

Author keywords

Antioxidants; Cognitive; Countermeasures; Inflammation; Morris water maze; Oxidative stress

Indexed keywords

ASTROBIOLOGY; BRAIN; IRRADIATION; NEUROLOGY; OXYGEN;

EID: 34249310995     PISSN: 02731177     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.asr.2006.11.005     Document Type: Article
Times cited : (21)

References (60)
  • 1
    • 0030184596 scopus 로고    scopus 로고
    • Spatial and visual discrimination learning in CD1 mice: partial analogy between the effect of lesions to the hippocampus and the amygdala
    • Ammassari-Teule M., and De Marsanich B. Spatial and visual discrimination learning in CD1 mice: partial analogy between the effect of lesions to the hippocampus and the amygdala. Physiol. Behav. 60 (1996) 265-271
    • (1996) Physiol. Behav. , vol.60 , pp. 265-271
    • Ammassari-Teule, M.1    De Marsanich, B.2
  • 2
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus R.T., Dean R.L., Beer B., and Lippa A.S. The cholinergic hypothesis of geriatric memory dysfunction. Science 217 (1982) 408-417
    • (1982) Science , vol.217 , pp. 408-417
    • Bartus, R.T.1    Dean, R.L.2    Beer, B.3    Lippa, A.S.4
  • 3
    • 0024730192 scopus 로고
    • The use of the Morris water maze in the study of memory and learning
    • Brandeis R., Brandys Y., and Yehuda S. The use of the Morris water maze in the study of memory and learning. Int. J. Neurosci. 48 (1989) 29-69
    • (1989) Int. J. Neurosci. , vol.48 , pp. 29-69
    • Brandeis, R.1    Brandys, Y.2    Yehuda, S.3
  • 8
    • 0030296888 scopus 로고    scopus 로고
    • Dissociation of hippocampal and striatal contributions to spatial navigation in the water maze
    • Devan B.D., Goad E.H., and Petri H.L. Dissociation of hippocampal and striatal contributions to spatial navigation in the water maze. Neurobiol. Learn. Mem. 66 (1996) 305-323
    • (1996) Neurobiol. Learn. Mem. , vol.66 , pp. 305-323
    • Devan, B.D.1    Goad, E.H.2    Petri, H.L.3
  • 9
    • 0028954228 scopus 로고
    • Age-related spatial reference and working memory deficits assessed in the water maze
    • Frick K.M., Baxter M.G., Markowska A.L., Olton D.S., and Price D.L. Age-related spatial reference and working memory deficits assessed in the water maze. Neurobiol. Aging 16 (1995) 149-160
    • (1995) Neurobiol. Aging , vol.16 , pp. 149-160
    • Frick, K.M.1    Baxter, M.G.2    Markowska, A.L.3    Olton, D.S.4    Price, D.L.5
  • 10
    • 0021139951 scopus 로고
    • Spatial learning and motor deficits in aged rats
    • Gage F.H., Dunnett S.B., and Bjorklund A. Spatial learning and motor deficits in aged rats. Neurobiol. Aging 5 (1984) 43-48
    • (1984) Neurobiol. Aging , vol.5 , pp. 43-48
    • Gage, F.H.1    Dunnett, S.B.2    Bjorklund, A.3
  • 11
    • 0024160442 scopus 로고
    • Spatial learning deficits in old rats: a model for memory decline in the aged
    • Gallagher M., and Pelleymounter M.A. Spatial learning deficits in old rats: a model for memory decline in the aged. Neurobiol. Aging 9 (1988) 549-556
    • (1988) Neurobiol. Aging , vol.9 , pp. 549-556
    • Gallagher, M.1    Pelleymounter, M.A.2
  • 12
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neruodegenerative diseases; therapeutic implications for antioxidant treatment
    • Halliwell B. Role of free radicals in the neruodegenerative diseases; therapeutic implications for antioxidant treatment. Drugs Aging 18 (2001) 685-716
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 13
    • 0033133362 scopus 로고    scopus 로고
    • The effects of a novel NSAID on chronic neuroinflammation are age dependent
    • Hauss-Wegrzyniak B., Vraniak P., and Wenk G.L. The effects of a novel NSAID on chronic neuroinflammation are age dependent. Neurobiol. Aging 20 (1999) 305-313
    • (1999) Neurobiol. Aging , vol.20 , pp. 305-313
    • Hauss-Wegrzyniak, B.1    Vraniak, P.2    Wenk, G.L.3
  • 14
    • 0034677723 scopus 로고    scopus 로고
    • Behavioral and ultrastructural changes induced by chronic neuroinflammation in young rats
    • Hauss-Wegrzyniak B., Vannucchi M.G., and Wenk G.L. Behavioral and ultrastructural changes induced by chronic neuroinflammation in young rats. Brain Res. 859 (2000) 157-166
    • (2000) Brain Res. , vol.859 , pp. 157-166
    • Hauss-Wegrzyniak, B.1    Vannucchi, M.G.2    Wenk, G.L.3
  • 15
    • 0038339921 scopus 로고    scopus 로고
    • Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation
    • Higuchi Y., Nelson G.A., Vazquez M., Laskowitz D.T., Slater J.M., and Pearlstein R.D. Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation. J. Radiat. Res. 43 Suppl. (2002) S219-S224
    • (2002) J. Radiat. Res. , vol.43 , Issue.SUPPL
    • Higuchi, Y.1    Nelson, G.A.2    Vazquez, M.3    Laskowitz, D.T.4    Slater, J.M.5    Pearlstein, R.D.6
  • 16
    • 0032473584 scopus 로고    scopus 로고
    • Water version of the radial-arm maze: learning in three inbred strains of mice
    • Hyde L.A., Hoplight B.J., and Denenberg V.H. Water version of the radial-arm maze: learning in three inbred strains of mice. Brain Res. 785 (1998) 236-244
    • (1998) Brain Res. , vol.785 , pp. 236-244
    • Hyde, L.A.1    Hoplight, B.J.2    Denenberg, V.H.3
  • 17
    • 0000515127 scopus 로고
    • Behavioral manifestations of aging
    • Mohr U., Cungworth D.L., and Capen C.C. (Eds), ILSI Press, Washington
    • Ingram D.K., Jucker M., and Spangler E. Behavioral manifestations of aging. In: Mohr U., Cungworth D.L., and Capen C.C. (Eds). Pathobiology of the Aging Rat Vol. 2 (1994), ILSI Press, Washington 149-170
    • (1994) Pathobiology of the Aging Rat , vol.2 , pp. 149-170
    • Ingram, D.K.1    Jucker, M.2    Spangler, E.3
  • 18
    • 0026897342 scopus 로고
    • The putative role of free radicals in the loss of neuronal functioning in senescence
    • Joseph J.A. The putative role of free radicals in the loss of neuronal functioning in senescence. Integr. Physiol. Behav. Sci. 27 (1992) 216-227
    • (1992) Integr. Physiol. Behav. Sci. , vol.27 , pp. 216-227
    • Joseph, J.A.1
  • 21
    • 0032243115 scopus 로고    scopus 로고
    • CNS effects of heavy particle irradiation in space: behavioral implications
    • Joseph J.A., Erat S., and Rabin B.M. CNS effects of heavy particle irradiation in space: behavioral implications. Adv. Space Res. 22 (1998) 209-216
    • (1998) Adv. Space Res. , vol.22 , pp. 209-216
    • Joseph, J.A.1    Erat, S.2    Rabin, B.M.3
  • 22
    • 0033568849 scopus 로고    scopus 로고
    • Reversals of age-related declines in neuronal signal transduction, cognitive and motor behavioral deficits with diets supplemented with blueberry, spinach, or strawberry dietary supplementation
    • Joseph J.A., Shukitt-Hale B., Denisova N.A., Bielinski D., Martin A., McEwen J.J., and Bickford P.C. Reversals of age-related declines in neuronal signal transduction, cognitive and motor behavioral deficits with diets supplemented with blueberry, spinach, or strawberry dietary supplementation. J. Neurosci. 19 (1999) 8114-8121
    • (1999) J. Neurosci. , vol.19 , pp. 8114-8121
    • Joseph, J.A.1    Shukitt-Hale, B.2    Denisova, N.A.3    Bielinski, D.4    Martin, A.5    McEwen, J.J.6    Bickford, P.C.7
  • 23
    • 0033641767 scopus 로고    scopus 로고
    • CNS-induced deficits of heavy particle irradiation in space: the aging connection
    • Joseph J.A., Shukitt-Hale B., McEwen J., and Rabin B.M. CNS-induced deficits of heavy particle irradiation in space: the aging connection. Adv. Space Res. 25 (2000) 2057-2064
    • (2000) Adv. Space Res. , vol.25 , pp. 2057-2064
    • Joseph, J.A.1    Shukitt-Hale, B.2    McEwen, J.3    Rabin, B.M.4
  • 24
    • 0036455153 scopus 로고    scopus 로고
    • Genetic determinants of adult hippocampal neurogenesis correlate with acquisition but not probe trial performance in the water maze task
    • Kempermann G., and Gage F.H. Genetic determinants of adult hippocampal neurogenesis correlate with acquisition but not probe trial performance in the water maze task. Eur. J. Neurosci. 16 (2002) 129-136
    • (2002) Eur. J. Neurosci. , vol.16 , pp. 129-136
    • Kempermann, G.1    Gage, F.H.2
  • 25
    • 0023854197 scopus 로고
    • Age difference of response strategy in radial maze performance of Fischer-344 rats
    • Kobayashi S., Kametani H., Ugawa Y., and Osanai M. Age difference of response strategy in radial maze performance of Fischer-344 rats. Physiol. Behav. 42 (1988) 277-280
    • (1988) Physiol. Behav. , vol.42 , pp. 277-280
    • Kobayashi, S.1    Kametani, H.2    Ugawa, Y.3    Osanai, M.4
  • 26
    • 0032192065 scopus 로고    scopus 로고
    • Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters
    • Luine V.N., Richards S.T., Wu V.Y., and Beck K.D. Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neurotransmitters. Horm. Behav. 34 (1998) 149-162
    • (1998) Horm. Behav. , vol.34 , pp. 149-162
    • Luine, V.N.1    Richards, S.T.2    Wu, V.Y.3    Beck, K.D.4
  • 27
    • 0028180587 scopus 로고
    • Parallel information processing in the water maze: evidence for independent memory systems involving dorsal striatum and hippocampus
    • McDonald R.J., and White N.M. Parallel information processing in the water maze: evidence for independent memory systems involving dorsal striatum and hippocampus. Behav. Neural Biol. 61 (1994) 260-270
    • (1994) Behav. Neural Biol. , vol.61 , pp. 260-270
    • McDonald, R.J.1    White, N.M.2
  • 28
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci. Meth. 11 (1984) 47-60
    • (1984) J Neurosci. Meth. , vol.11 , pp. 47-60
    • Morris, R.1
  • 29
  • 31
    • 0032251768 scopus 로고    scopus 로고
    • Effects of exposure to different types of radiation on behaviors mediated by peripheral or central systems
    • Rabin B.M., Joseph J.A., and Erat S. Effects of exposure to different types of radiation on behaviors mediated by peripheral or central systems. Adv. Space Res. 22 (1998) 217-225
    • (1998) Adv. Space Res. , vol.22 , pp. 217-225
    • Rabin, B.M.1    Joseph, J.A.2    Erat, S.3
  • 32
    • 0033654352 scopus 로고    scopus 로고
    • Effects of exposure to heavy particles on a behavior mediated by the dopaminergic system
    • Rabin B.M., Joseph J.A., Shukitt-Hale B., and McEwen J. Effects of exposure to heavy particles on a behavior mediated by the dopaminergic system. Adv. Space Res. 25 (2000) 2065-2074
    • (2000) Adv. Space Res. , vol.25 , pp. 2065-2074
    • Rabin, B.M.1    Joseph, J.A.2    Shukitt-Hale, B.3    McEwen, J.4
  • 33
    • 0034839629 scopus 로고    scopus 로고
    • 56 Fe particles on the acquisition of a conditioned place preference in rats
    • 56 Fe particles on the acquisition of a conditioned place preference in rats. Phys. Med. 27 Suppl. 1 (2001) 196-197
    • (2001) Phys. Med. , vol.27 , Issue.SUPPL. 1 , pp. 196-197
    • Rabin, B.M.1    Shukitt-Hale, B.2    Joseph, J.A.3    Denissova, N.4
  • 35
    • 0037145739 scopus 로고    scopus 로고
    • Effects of heavy particle irradiation and diet on amphetamine- and lithium chloride-induced taste aversion learning in rats
    • Rabin B.M., Shukitt-Hale B., Szprengiel B., and Joseph J.A. Effects of heavy particle irradiation and diet on amphetamine- and lithium chloride-induced taste aversion learning in rats. Brain Res. 953 (2002) 31-36
    • (2002) Brain Res. , vol.953 , pp. 31-36
    • Rabin, B.M.1    Shukitt-Hale, B.2    Szprengiel, B.3    Joseph, J.A.4
  • 37
    • 2342558085 scopus 로고    scopus 로고
    • Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function
    • Rabin B.M., Joseph J.A., and Shukitt-Hale B. Heavy particle irradiation, neurochemistry and behavior: thresholds, dose-response curves and recovery of function. Adv. Space Res. 33 (2004) 1330-1333
    • (2004) Adv. Space Res. , vol.33 , pp. 1330-1333
    • Rabin, B.M.1    Joseph, J.A.2    Shukitt-Hale, B.3
  • 38
  • 40
    • 13844276687 scopus 로고    scopus 로고
    • Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic rays
    • Rabin B.M., Joseph J.A., and Shukitt-Hale B. Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic rays. Brain Res. 1036 (2005) 122-129
    • (2005) Brain Res. , vol.1036 , pp. 122-129
    • Rabin, B.M.1    Joseph, J.A.2    Shukitt-Hale, B.3
  • 41
    • 25444489288 scopus 로고    scopus 로고
    • A longitudinal study of operant responding in rats irradiated when two months old
    • Rabin B.M., Joseph J.A., and Shukitt-Hale B. A longitudinal study of operant responding in rats irradiated when two months old. Radiat. Res. 164 (2005) 552-555
    • (2005) Radiat. Res. , vol.164 , pp. 552-555
    • Rabin, B.M.1    Joseph, J.A.2    Shukitt-Hale, B.3
  • 42
    • 26944459671 scopus 로고    scopus 로고
    • Diet as a factor in behavioral radiation protection following exposure to heavy particles
    • Rabin B.M., Shukitt-Hale B., Joseph J., and Todd P. Diet as a factor in behavioral radiation protection following exposure to heavy particles. Gravit. Space Biol. 18 (2005) 71-77
    • (2005) Gravit. Space Biol. , vol.18 , pp. 71-77
    • Rabin, B.M.1    Shukitt-Hale, B.2    Joseph, J.3    Todd, P.4
  • 43
    • 34249331436 scopus 로고    scopus 로고
    • Rabin, B.M., Shukitt-Hale, B., Joseph, J.A., Carrihill-Knoll, K.L., Carey, A.N., and Cheng, V. Relative effectiveness of different particles and energies in disrupting behavioral performance. Radiat. Environ. Biophys. (in press).
  • 44
    • 0023139908 scopus 로고
    • An evaluation of spatial information processing in aged rats
    • Rapp P.R., Rosenberg R.A., and Gallagher M. An evaluation of spatial information processing in aged rats. Behav. Neurosci. 101 (1987) 3-12
    • (1987) Behav. Neurosci. , vol.101 , pp. 3-12
    • Rapp, P.R.1    Rosenberg, R.A.2    Gallagher, M.3
  • 46
    • 0027954494 scopus 로고
    • Free radicals in biology: oxidative stress and the effects of ionizing radiation
    • Riley P.A. Free radicals in biology: oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol. 65 (1994) 27-33
    • (1994) Int. J. Radiat. Biol. , vol.65 , pp. 27-33
    • Riley, P.A.1
  • 47
    • 3042799716 scopus 로고    scopus 로고
    • Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice
    • Rola R., Raber J., Rizk A., Otsuka S., VandenBerg S.R., Morhardt D.R., and Fike J.R. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice. Exp. Neurol. 188 (2004) 316-330
    • (2004) Exp. Neurol. , vol.188 , pp. 316-330
    • Rola, R.1    Raber, J.2    Rizk, A.3    Otsuka, S.4    VandenBerg, S.R.5    Morhardt, D.R.6    Fike, J.R.7
  • 48
    • 0026691316 scopus 로고
    • Object exploration and reactions to spatial and nonspatial changes in hooded rats following damage to parietal cortex or hippocampal formation
    • Save E., Poucet B., Foreman N., and Buhot M.C. Object exploration and reactions to spatial and nonspatial changes in hooded rats following damage to parietal cortex or hippocampal formation. Behav. Neurosci. 106 (1992) 447-456
    • (1992) Behav. Neurosci. , vol.106 , pp. 447-456
    • Save, E.1    Poucet, B.2    Foreman, N.3    Buhot, M.C.4
  • 49
    • 0032942833 scopus 로고    scopus 로고
    • The effects of aging and oxidative stress on psychomotor and cognitive behavior
    • Shukitt-Hale B. The effects of aging and oxidative stress on psychomotor and cognitive behavior. Age 22 (1999) 9-17
    • (1999) Age , vol.22 , pp. 9-17
    • Shukitt-Hale, B.1
  • 50
    • 0032164057 scopus 로고    scopus 로고
    • Psychomotor and spatial memory performance in aging male Fischer 344 rats
    • Shukitt-Hale B., Mouzakis G., and Joseph J.A. Psychomotor and spatial memory performance in aging male Fischer 344 rats. Exp. Gerontol. 33 (1998) 615-624
    • (1998) Exp. Gerontol. , vol.33 , pp. 615-624
    • Shukitt-Hale, B.1    Mouzakis, G.2    Joseph, J.A.3
  • 52
    • 0034806925 scopus 로고    scopus 로고
    • Effects of age on object exploration, habituation and response to spatial and non-spatial change
    • Shukitt-Hale B., Casadesus G., Cantuti-Castelvetri I., and Joseph J.A. Effects of age on object exploration, habituation and response to spatial and non-spatial change. Behav. Neurosci. 115 (2001) 1059-1064
    • (2001) Behav. Neurosci. , vol.115 , pp. 1059-1064
    • Shukitt-Hale, B.1    Casadesus, G.2    Cantuti-Castelvetri, I.3    Joseph, J.A.4
  • 54
    • 1642553467 scopus 로고    scopus 로고
    • Effect of age on the radial arm water maze - a test of spatial learning and memory
    • Shukitt-Hale B., McEwen J.J., Szprengiel A., and Joseph J.A. Effect of age on the radial arm water maze - a test of spatial learning and memory. Neurobiol. Aging 25 (2004) 223-229
    • (2004) Neurobiol. Aging , vol.25 , pp. 223-229
    • Shukitt-Hale, B.1    McEwen, J.J.2    Szprengiel, A.3    Joseph, J.A.4
  • 56
    • 34249330420 scopus 로고    scopus 로고
    • Shukitt-Hale, B., Carey, A.N., Jenkins, D., Rabin, B.M., Joseph J.A. Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging. Neurobiol. Aging (in press).
  • 57
    • 0018852193 scopus 로고
    • Animal models of declining memory in the aged: short-term and spatial memory in the aged rat
    • Wallace J.E., Krauter E.E., and Campbell B.A. Animal models of declining memory in the aged: short-term and spatial memory in the aged rat. J. Gerontol. 35 (1980) 355-363
    • (1980) J. Gerontol. , vol.35 , pp. 355-363
    • Wallace, J.E.1    Krauter, E.E.2    Campbell, B.A.3
  • 58
    • 0001601781 scopus 로고    scopus 로고
    • Total antioxidant capacity of fruits
    • Wang H., Cao G., and Prior R.L. Total antioxidant capacity of fruits. J. Agric. Food Chem. 44 (1996) 701-705
    • (1996) J. Agric. Food Chem. , vol.44 , pp. 701-705
    • Wang, H.1    Cao, G.2    Prior, R.L.3
  • 59
    • 0000863877 scopus 로고    scopus 로고
    • Short-term dietary supplementation of blueberry polyphenolics: beneficial effects on aging brain performance and peripheral tissue function
    • Youdim K.A., Shukitt-Hale B., Martin A., Wang H., Denisova N., Bickford P.C., and Joseph J.A. Short-term dietary supplementation of blueberry polyphenolics: beneficial effects on aging brain performance and peripheral tissue function. Nutr. Neurosci. 3 (2000) 383-391
    • (2000) Nutr. Neurosci. , vol.3 , pp. 383-391
    • Youdim, K.A.1    Shukitt-Hale, B.2    Martin, A.3    Wang, H.4    Denisova, N.5    Bickford, P.C.6    Joseph, J.A.7
  • 60
    • 0029170919 scopus 로고
    • Cognitive decline associated with normal aging in rats: a neuropsychological approach
    • Zyzak D.R., Otto T., Eichenbaum H., and Gallagher M. Cognitive decline associated with normal aging in rats: a neuropsychological approach. Learn. Mem. 2 (1995) 1-16
    • (1995) Learn. Mem. , vol.2 , pp. 1-16
    • Zyzak, D.R.1    Otto, T.2    Eichenbaum, H.3    Gallagher, M.4


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