Effects of 2 concentrations of sodium citrate on coagulation test results, von Willebrand factor concentration, and platelet function in dogs

Journal of Veterinary Internal Medicine

Volumn 21, Issue 3, 2007, Pages 472-475

  Morales, F ^a   Couto, C G ^a,b,c   Iazbik, M C ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c ACVIM   (United States)

Author keywords

Activated partial thromboplastin time (aPTT); Anticoagulant; Canine; One stage prothrombin time (OSPT); PFA 100

Indexed keywords

BUFFER; CITRATE SODIUM; CITRIC ACID; FIBRINOGEN; VON WILLEBRAND FACTOR;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BLOOD CLOTTING PARAMETERS; BLOOD SAMPLING; DOG; DOSE RESPONSE; FEMALE; INSTRUMENTATION; MALE; METHODOLOGY; PARTIAL THROMBOPLASTIN TIME; PROTHROMBIN TIME; THROMBOCYTE COUNT;

ANIMALS; BLOOD SPECIMEN COLLECTION; BUFFERS; CITRATES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBRINOGEN; MALE; PARTIAL THROMBOPLASTIN TIME; PLATELET COUNT; PLATELET FUNCTION TESTS; PROTHROMBIN TIME; VON WILLEBRAND FACTOR;

ANIMALIA; CANIS FAMILIARIS;

EID: 34249302722     PISSN: 08916640     EISSN: None     Source Type: Journal    
DOI: 10.1892/0891-6640(2007)21[472:EOCOSC]2.0.CO;2     Document Type: Article

References (13)

1. Couto CG. Disorders of hemostasis. In: Nelson R, Couto CG, eds. Small Animal Internal Medicine, 3rd ed. St Louis, MO: Mosby; 2003:1185-1199.
2. Jilma B. Platelet function analyzer (PFA-100): A tool to quantify congenital or acquired platelet dysfunction. J Lab Clin Med 2001;138:152-163.
3. Mischke R, Keidel A. Influence of platelet count, acetylsalicylic acid, von Willebrands disease, coagulopathies, and haematocrit on results obtained using a platelet function analyser in dogs. Vet J 2003;165:43-52.
4. Callan MB, Giger U. Assessment of a point-of-care instrument for identification of primary hemostatic disorders in dogs. Am J Vet Res 2001;62:652-658.
5. Couto CG, Lara A, Iazbik MC, Brooks M. Evaluation of platelet aggregation using a point-of-care instrument (PFA-100®) in retired racing Greyhounds. J Vet Intern Med 2006;20:365-370.
6. Stokol TB, Brooks MB, Erb HN. Effect of citrate concentration on coagulation test results in dogs. J Am Vet Med Assoc 2000;217:1672-1677.
7. Reneke J, Etzell J, Leslie S, et al. Prolonged prothrombin time and activated partial thromboplastin time due to underfilled specimen tubes with 109 mmol/L (3.2%) citrate anticoagulant. Am J Clin Pathol 1998;109:754-757.
8. Heilmann EJ, Kundu SK, Sio R, et al. Comparison of four commercial citrate blood collection systems for platelet function analysis by the PFA-100® system. Thromb Res 1997;87:159-154.
9. Benson RE, Catalfamo JL, Brooks M, Dodds WJ. A sensitive immunoassay for von Willebrand factor. J Immunoassay 1991;12:371-390.
10. Chantanarangkul V, Tripodi A, Clerici M, et al. Assessment of the influence of citrate concentration on the international normalized ratio (INR) determined with twelve reagent-instrument combinations. Thromb Haemost 1998;80:258-262.
11. von Pape KW, Aland E, Bohner J. Platelet function analysis with PFA-100® in patients medicated with acetylsalicylic acid strongly depends on concentration of sodium citrate for anticoagulation of blood sample. Thromb Res 2000;98:295-299.
12. Rinder HM. Platelet function testing by flow cytometry. J Am Society Clin Lab Science 1998; 11:365-372.
13. Hay J, Arnott MA. Ivermectin and coagulation: An in vitro study. Ann Trop Med Parasitol 1998;84:503-506.