Assessment of a point-of-care instrument for identification of primary hemostatic disorders in dogs

American Journal of Veterinary Research

Volumn 62, Issue 5, 2001, Pages 652-658

  Callan, Mary Beth ^a   Giger, Urs ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CANIS FAMILIARIS;

ADENOSINE DIPHOSPHATE; ADRENALIN; COLLAGEN; DIAGNOSTIC AGENT;

ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BLOOD CLOTTING DISORDER; BLOOD CLOTTING TEST; DOG; DOG DISEASE; EVALUATION; FEMALE; INSTRUMENTATION; MALE; PREDICTION AND FORECASTING; SENSITIVITY AND SPECIFICITY; STANDARD; THROMBOCYTOPENIA; VON WILLEBRAND DISEASE;

ADENOSINE DIPHOSPHATE; ANIMALS; BLOOD COAGULATION DISORDERS; BLOOD COAGULATION TESTS; COLLAGEN; DOG DISEASES; DOGS; EPINEPHRINE; FEMALE; MALE; PREDICTIVE VALUE OF TESTS; SENSITIVITY AND SPECIFICITY; THROMBOCYTOPENIA; VON WILLEBRAND DISEASE;

EID: 0035344529     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2001.62.652     Document Type: Article

References (38)

1. Tvedten H. Hemostatic abnormalities. In: Willard MD, Tvedten H, Turnwald GH, eds. Small animal clinical diagnosis by laboratory methods. 2nd ed. Philadelphia: WB Saunders Co, 1994;81-95.
2. Giger U, Brooks M, Dodds WJ, et al. Advances in canine von Willebrand disease, in Proceedings. 18th Annu Meet Vet Med Forum 2000;481-482.
3. Jergens AE, Turrentine MA, Kraus KH, et al. Buccal mucosa bleeding times of healthy dogs and dogs in various pathologic states, including thrombocytopenia, uremia, and von Willebrand's disease. Am J Vet Res 1987;48:1337-1342.
4. Cattaneo M, Federici AB, Lecchi A, et al. Evaluation of the PFA-100® system in the diagnosis and therapeutic monitoring of patients with von Willebrand disease. Thromb Haemost 1999;82:35-34.
5. Fressinaud E, Veyradier A, Truchaud F, et al. Screening for von Willebrand disease with a new analyzer using high shear stress: a study of 60 cases. Blood 1998;91:1325-1331.
6. Kerenyi A, Schlammadinger A, Ajzner E, et al. Comparison of PFA-100 closure time and template bleeding time of patients with inherited disorders causing defective platelet function. Thromb Res 1999;96:487-492.
7. Mammen EF, Comp PC, Gosselin R, et al. PFA-100™ system: a new method for assessment of platelet dysfunction. Semin Thromb Hemost 1998;24:195-202.
8. Harrison P, Robinson MSC, Mackie IJ, et al. Performance of the platelet function analyzer PFA-100® in testing abnormalities of primary hemostasis. Blood Coagul Fibrinolysis 1999;10:25-31.
9. Favaloro EJ, Facey D, Henniker A. Use of a novel platelet function analyzer (PFA-100™) with a high sensitivity to disturbances in von Willebrand factor to screen for von Willebrand disease and other disorders. Am J Hematol 1999;62:165-174.
10. Bennett JS. Platelet aggregation. In: Williams WJ, Beutler E, Erslev AJ, et al, eds. Hemtology. 4th ed. New York: McGraw-Hill Book Co, 1990;1778-1781.
11. Callan MB, Bennett JS, Phillips DK, et al. Inherited platelet d-storage pool disease in dogs causing severe bleeding: an animal model for a specific ADP deficiency. Thromb Haemost 1995;74:949-953.
12. Kundu SK, Heilmann EJ, Sio R, et al. Description of an in vitro platelet function analyzer - PFA-100™. Semin Thromb Hemost 1995;21:106-112.
13. Kundu SK, Heilmann EJ, Sio R, et al. Characterization of an in vitro platelet function analyzer, PFA-100™. Clin Appl Thromb/Hemost 1996;2:241-249.
14. Brooks M, Catalfamo J. Buccal mucosa bleeding time is prolonged in canine models of primary hemostatic disorders. Thromb Haemost 1993;70:777-780.
15. Catalfamo JL, Dodds WJ. Isolation of platelets from laboratory animals. In: Hawiger J, ed. Methods in enzymology. Vol 169. San Diego: Academic Press Inc, 1989;27-34.
16. Eksell P, Haggstrom J, Kvart C, et al. Thrombocytopenia in the cavalier King Charles spaniel. J Small Anim Pract 1994;35:153-155.
17. Brown SJ, Simpson KW, Baker S, et al. Macrothrombocytosis in cavalier King Charles spaniels. Vet Rec 1994;135:281-283.
18. Smedile LE, Houston DM, Taylor SM, et al. Idiopathic, asymptomatic thrombocytopenia in Cavalier King Charles spaniels. J Am Anim Hosp Assoc 1997;33:411-415.
19. Callan MB, Walton R, Jezyk PF, et al. Thrombopathias causing bleeding in a Boxer and mixed breed dog. J Am Anim Hosp Assoc 2001;37:in press.
20. IIb are associated with type 1 Glanzmann's thrombasthenia in a Great Pyrenees dog: a 14-base insertion in exon 13 and a splicing defect of intron 13. Vet Pathol 2000;37:581-588.
21. Boudreaux MK, Crager C, Dillon AR, et al. Identification of an intrinsic platelet function defect in Spitz dogs. J Vet Intern Med 1994;8:93-98.
22. Boudreaux MK, Lipscomb DL. Clinical, biochemical, and molecular aspects of Glanzmann's thrombasthenia in otterhounds. Am J Vet Res 2001;in press.
23. Catalfamo JL, Raymond SL, White JG, et al. Defective platelet-fibrinogen interaction in hereditary canine thrombopathia. Blood 1986;67:1568-1577.
24. Brooks M, Catalfamo JL. Platelet dysfunction. In: Bonagura JD, ed. Kirk's current veterinary therapy XIII. Philadelphia: WB Saunders Co, 2000;442-447.
25. Keidel A, Mischke R. Untersuchungen zur klinischen anwendung des plättchenfunktionsananlysengerätes PFA-100 beim hund. Berl Munch Tierarztl Wochenschr 1998;111:452-456.
26. Dodds WJ. Hemostasis. In: Kaneko JJ, Harvey JW, Bruss ML, eds. Clinical biochemistry of domestic animals. 5th ed. San Diego: Academic Press Inc, 1997;241-283.
27. Clemmons RM, Meyers KM. Acquisition and aggregation of canine blood platelets: basic mechanisms of function and differences because of breed origin. Am J Vet Res 1484;45:137-144.
28. Feingold HM, Pracek LE, Melarango AJ, et al. Coagulation assays and platelet aggregation patterns in human, baboon, and canine blood. Am J Vet Res 1986;47:2197-2199.
29. Macmillan DC, Sim AK. A comparative study of platelet aggregation in man and laboratory animals. Thromb Diath Haemorrh 1970;24:385-394.
30. Livio M, Marchesi D, Remuzzi G, et al. Uraemic bleeding: role of anemia and beneficial effect of red cell transfusions. Lancet 1982;2:1013-1015.
31. Fernandez F, Goudable C, Sie P, et al. Low haematocrit and prolonged bleeding time in uraemic patients: effect of red cell transfusions. Br J Haematol 1985;59:139-148.
32. Blajchman MA, Bordin JO, Bardossy L, et al. The contribution of the haematocrit to thrombocytopenic bleeding in experimental animals. Br J Haematol 1994;86:347-350.
33. Gewirtz AS, Miller ML, Keys TF. The clinical usefulness of the preoperative bleeding time. Arch Pathol Lab Med 1996;120:353-356.
34. O'Kelly SW, Lawes EG, Luntley JB. Bleeding time: is it a clinically useful tool? Br J Anaesth 1992;68:313-315.
35. Brooks M, Dodds WJ, Raymond SL. Epidemiologic features of von Willebrand's disease in Doberman Pinschers, Scottish Terriers, and Shetland Sheepdogs: 260 cases (1984-1988). J Am Vet Med Assoc 1992;200:1123-1127.
36. Lind SE. The bleeding time does not predict surgical bleeding. Blood 1991;77:2547-2552.
37. Rodgers RPC, Levin J. A critical reappraisal of the bleeding time. Semin Thromb Hemost 1990;16:1-20.
38. Fressinaud E, Veyradier A, Sigaud M, et al. Therapeutic monitoring of von Willebrand disease: interest and limits of a platelet function analyzer at high shear rates. Br J Haematol 1999;106:777-783.