Effect of radicicol infusion on the Src tyrosine kinase activity of rat hippocampus before and after training in an inhibitory avoidance task

Neurochemical Research

Volumn 32, Issue 7, 2007, Pages 1150-1155

  Pereira, Patrícia ^a,b   Vinadé, Elsa ^a   Rodrigues, Letícia ^a   De David E Silva, Tiago L ^a   Ardenghi, Patrícia ^a,c   Da Silva Brum, Lucimar Filot ^b   Gonçalves, Carlos Alberto ^a   Izquierdo, Iván ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^c UNIVERSIDADE FEEVALE   (Brazil)

Author keywords

Hippocampus; Memory; Radicicol; Src tyrosine kinases

Indexed keywords

PROTEIN TYROSINE KINASE; RADICICOL;

ANIMAL EXPERIMENT; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; ENZYME ACTIVITY; HIPPOCAMPUS; MALE; MEMORY; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; TASK PERFORMANCE; TRAINING;

ANIMALS; AVOIDANCE LEARNING; ENZYME INHIBITORS; HIPPOCAMPUS; MACROLIDES; MALE; MEMORY; RATS; RATS, WISTAR; SRC-FAMILY KINASES;

RATTUS;

EID: 34249293026     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-007-9284-2     Document Type: Article

References (34)

1. Izquierdo I, Medina JH (1997) Memory formation: the sequence of biochemical events in the hippocampus and its connection to activity in other brain structures. Neurobiol Learn Mem 68(3):285-316
2. Micheau J, Riedel G (1999) Protein kinases: which one is the memory molecule? Cell Mole Life Sci 55:534-548
3. Abel T, Lattal KM (2001) Molecular mechanisms of memory acquisition, consolidation and retrieval. Curr Opin Neurobiol 11(2):180-187
4. Bernabeu R, Bevilaqua L, Ardenghi P, Bromberg E, Schmitz P, Bianchin M, Izquierdo I, Medina JH (1997) Involvement of hippocampal D1/D5 receptor-cAMP signalling pathways in a late memory consolidation phase of an aversively-motivated task in rats. Proc Natl Acad Sci USA 94:7041-7046
5. Routtemberg A, Cantallops I, Zaffuto S, Serrano P, Namgung U (2000) Enhance learning after genetic overexpression of a brain growth protein. Proc Natl Acad Sci USA 97(13):7657-7662
6. Paratcha G, Furman M, Bevilaqua L, Camarotta M, Vianna M, de Stein ML, Izquierdo I, Medina JH (2000) Involvement of hippocampal PKCbetaI isoform in the early phase of memory formation of on inhibitory avoidance learning. Brain Res 855(2):199-205
7. Cammarota M, Bernabeu R, Levi de Stein M, Izquierdo I, Medina JH (1998) Learning-specific, time-dependent increases in hippocampal Ca2+/calmodulin- dependent protein kinase II activity and AMPA GluR1 subunit immunoreactivity. Eur J Neurosci 10(8):2669-2676
8. Walz R, Roesler R, Quevedo J, Rockenback IC, Amaral OB, Vianna MR, Lenz G, Medina JH, Izquierdo I (1999) Dose-dependent impairment of inhibitory avoidance retention in rats by immediate post-training infusion of a mitogen-activated protein kinase kinase inhibitor into cortical structures. Behav Brain Res 105(2):219-223
9. Alonso M, Vianna MR, Depino AM, Mello e Souza T, Pereira P, Szapiro G, Viola H, Pitossi F, Izquierdo I, Medina JH (2002) BDNF-triggered events in the rat hippocampus are required for both short- and long-term memory formation. Hippocampus 12(4):551-560
10. Grant SGN, O'Dell TJ, Karl KA, Stein PL, Soriano P, Kandel ER (1992) Impaired long-term potentiation, spatial learning, and hippocampal development in Fyn-PTK mutant mice. Science 258:1903-1909
11. Brown MT, Cooper JA (1996) Regulation, substrates and functions of Src. Biochim Biophys Acta 1287:121-149
12. Huang CC, Hsu KS (1999) Protein tyrosine kinase is required for the induction of long-term potentiation in the rat hippocampus. J Physiol 3:783-796
13. Rosemblum K, Schul R, Meiri N, Hadari YR, Zick Y, Dudai Y (1995) Modulation of protein tyrosine phosphorylation in rat insular cortex after conditioned taste aversion training. Proc Natl Acad Sci USA 92:1157-1161
14. Izquierdo LA, Barros DM, Ardenghi PG, Pereira P, Rodríguez C, Choi H, Medina JH, Izquierdo I (2000) Different hippocampal molecular requirements for short- and long-term retrieval of one-trial avoidance learning. Behav Brain Res 111:93-98
15. Thomas SM, Brugge JS (1997) Cellular functions regulated by Src family kinases. Annu Rev Cell Dev Biol 13:513-609
16. Lindén A, Storvik M, Lakso M, Haapasalo A, Lee D, Witkin JM, Sli Y, Castren E, Wong G (2001) Increased expresión of neuronal Src and tyrosine phosphorylation of NMDA receptors in rat brain after systemic treatment with MK-801. Neuropharmacology 40:469-481
17. Soga S, Kozawa T, Narumi H, Akinaga S, Irie K, Matsumoto K, Sharma SV, Nakano H, Mizukami T, Hara M (1998) Radicicol leads to selective depletion of Raf kinase and disrupts K-Ras-activated aberrant signaling pathway. J Biol Chem 9:822-828
18. Ki SW, Kasahara K, Know HJ, Eishima J, Takesako K, Cooper JA, Yoshida M, Horinouchi S (1998) Identification of radicicol as an inhibitor of in vivo Ras/Raf interaction with the yeast two-hybrid screening system. J Antibiot 51:936-944
19. Kwon HJ, Yoshida M, Fukui Y, Horinouchi S, Beppu T (1992) Potent and specific inhibition of p60c-Src protein kinase both in vivo and in vitro by radicicol. Cancer Res 52:6926-6930
20. Sano M, Yoshida M, Fukui S, Kitajima S (1999) Radicicol potentiates neurotrophin-mediated neurite out growth and survival of culture sensory neurons from chick embryo. J Neurochem 72:2256-2263
21. Zhao W, Cavallaro S, Gusev P, Alkon DL (2000) Nonreceptor tyrosine protein kinase pp60c-Src in spatial learning: synapse-specific changes in its gene expression, tyrosine phosphorylation, and protein-protein interactions. Proc Natl Acad Sci USA 97:8098-8103
22. Pereira P, Ardenghi P, Souza MM, Choi H, Moletta B, Izquierdo I (2001) Effects of infusions of tyrosine kinase inhibitor radicicol into the hippocampus on short-and long-term memory of the inhibitory avoidance task. Behav Pharmacol 12:299-302
23. Bevilaqua LR, Rossato JI, Medina JH, Izquierdo I, Cammarota M (2003) Src kinase activity is required for avoidance memory formation and recall. Behav Pharmacol 14(8):649-652
24. Paxinos G, Watson C (1986) (eds) The rat brain in stereotaxic coordinates, 2nd edn. Academic Press, San Diego
25. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quanties of protein utilizing the principle of dye-binding. Anal Biochem 72:248-254
26. Islas-Flores I, Oropeza C, Hernández-Sotomayor SMT (1998) Protein phosphorylation during coconut zygotic embryo development. Plant Physiol 118:257-263
27. McGaugh JL (2000) Memory-a century of consolidation. Science 287:248-251
28. Izquierdo I (1989) Different forms of post-training memory processing. Behav Neural Biol 51(2):171-202
29. Ardenghi P, Barros D, Izquierdo LA, Bevilaqua L, Schoder N, Quevedo C, Madruga, Medina JH, Izquierdo I (1997) Late and prolonged post-training memory modulation in entorhinal and parietal cortex by drugs acting on the cAMP/protein kinase A signalling pathway. Behav Pharmacol 8(8):745-751
30. Izquierdo LA, Vianna M, Barros DM, Mello e Souza T, Ardenghi P, Sant' Anna MK, Rodrigues C, Medina JH, Izquierdo I (2000) Short- and long-term memory are differentially affected by metabolic inhibitors given into hippocampus and entorhinal cortex. Neurobiol Learn Mem 73(2):141-149
31. Izquierdo I, Medina JH, Vianna MR, Izquierdo LA, Barros DM (1999) Separate mechanisms for short- and long-term memory. Behav Brain Res 103(1):1-11
32. Vianna MR, Izquierdo LA, Barros DM, Ardenghi P, Pereira P, Rodríguez C,Molleta B, Medina JH, Izquierdo I (2000) Differential role of hippocampal cAMP-dependent protein kinase in short- and long-term memory. Neurochem Res 25(5):621-626
33. Szapiro G, Izquierdo LA, Alonso M, Barros D, Paratcha G, Ardenghi P, Pereira P, Medina JH, Izquierdo I (2000) Participation of hippocampal metabotropic glutamate receptor protein kinase A and mitogen-activated protein kinase in memory retrieval. Neuroscience 99(1):1-5
34. Ali DW, Salter MW (2001) NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol 11:336-342