Inhibition of sonic hedgehog signaling reduces chronic rejection and prolongs allograft survival in a rat orthotopic small bowel transplantation model

Transplantation

Volumn 83, Issue 10, 2007, Pages 1351-1357

  Chen, Yan ^a   Li, Xiaosong ^a,b   Tian, Lina ^a,c   Lui, Vincent C H ^a   Dallman, Margaret J ^d   Lamb, Jonathan R ^e   Tam, Paul K H ^a,f  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b CAPITAL MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF SYDNEY   (Australia)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chronic rejection; Sonic hedgehog; Vascular endothelial growth factor

Indexed keywords

IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; SONIC HEDGEHOG ANTIBODY; SONIC HEDGEHOG PROTEIN; TACROLIMUS; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL; BLOOD VESSEL OCCLUSION; CONTROLLED STUDY; GRAFT REJECTION; GRAFT SURVIVAL; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE GRAFT; INTESTINE TRANSPLANTATION; MACROPHAGE; MALE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE;

ANIMALS; GRAFT REJECTION; GRAFT SURVIVAL; HEDGEHOG PROTEINS; INTESTINE, SMALL; MALE; MODELS, ANIMAL; RATS; RATS, INBRED LEW; RATS, INBRED STRAINS; SIGNAL TRANSDUCTION; TRANSPLANTATION, HOMOLOGOUS;

EID: 34249109356     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.tp.0000262568.73590.81     Document Type: Article

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