Reduction of rat myocardial ischemia and reperfusion injury by sialyl Lewis x oligosaccharide and anti-rat P-selectin antibodies

Glycobiology

Volumn 6, Issue 4, 1996, Pages 463-469

  Tojo, Shinichiro J ^a   Yokota, Shin Ichi ^a   Koike, Haruhiko ^a   Schultz, Jody ^b   Hamazume, Yasuki ^a   Misugi, Emi ^a   Yamada, Kazuto ^a   Hayashi, Masaji ^a   Paulson, James C ^b   Morooka, Shigeaki ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

^b CYTEL CORPORATION   (United States)

Author keywords

Ischemia and reperfusion injury; Lewis x; Monoclonal antibodies; Selectins; Sialyl

Indexed keywords

LEAD; MONOCLONAL ANTIBODY; OLIGOSACCHARIDE; PADGEM PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; THROMBOCYTE;

ANIMALIA;

EID: 0029779592     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/6.4.463     Document Type: Article

References (42)

1. Auchampach, J.A., Oliver, M.G., Anderson, D.C. and Manning, A.M. (1994) Cloning, sequence comparison and in vivo expression of the gene encoding rat P-selectin. Gene, 145, 251-255.
2. Bevilacqua, M.P., Stengelin, S., Gimbrone, M.A. and Seed, B. (1989) Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science, 243, 1160-1165.
3. Buerke, M. Weyrich, A.S., Zheng, Z., Gaeta, F.C A., Forrest, M.J. and Lefer, A.M. (1994) Sialy Lewis X-containing oligosaccharide attenuates myocardial reperfusion injury in cats. J. Clin. Invest., 93, 1140-1148.
4. Celi, A. Pellegrini, G., Lorenzet, R., Blasi, A.D., Ready, N., Furie, B.C. and Furie, B. (1994) P-selectin induces the expression of tissue factor on monocytes Proc. Natl. Acad. Sci. USA, 91, 8767-8771.
5. Chen, L.Y., Nichols, W.W., Hendricks, J.B., Yang, B.C. and Mehta, J.L. (1994) Monoclonal antibody to P-selectin (PB 1.3) protects against myocardial reperfusion injury in dog. Cardiovasc. Res., 28, 1414-1422.
6. Elstad, M.R., La Pine, T.R., Cowley, F.S., McEver, R.P., McIntyre, T.M., Prescott, S.M. and Zimmerman, G.A. (1995) P-selectin regulates platelet-activating factor synthesis and phagocytosis by monocytes. J. Immunol., 155, 2109-2122.
7. Grober, J.S., Bowen, B.L., Ebling, H., Athey, B., Thompson, C.B., Fox, D.A. and Stoolman, L.M. (1993) Monocyte-endothelial adhesion in chronic rheumatoid arthritis. In situ detection of selectin and integrin-dependent interactions. J. Clin. Invest., 91, 2609-2619.
8. Hansen, P.R (1995) Role of neutrophils in myocardial ischemia and reperfusion. Circulation, 91, 1872-1885.
9. Hahne, M., Jäger,U., Isenmann, S., Hallmann, R. and Vestweber, D. (1993) Five tumor necrosis factor-inducible cell adhesion mechanisms on the surface of mouse endothelioma cells mediate the binding of leukocytes. J. Cell. Biol., 121, 655-664.
10. x analogs. J. Org. Chem., in press.
11. Johnston, G.I. Cook, R.G. and McEver, R.P. (1989) Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation. Cell, 56, 1033-1044.
12. Kloner, R.A., Przyklenk, K. and Whittaker, P. (1989) Deleterious effects of oxygen radicals in ischemia/reperfusion: resolved and unresolved issues. Circulation, 80, 1115-1127.
13. Kriegler, M.P (1990) Gene Transfer and Expression: A Laboratory Manual. W.H. Freeman, New York.
14. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature, 227, 680-685.
15. Laski, L., Singer, M.A., Yednock, T.A., Dowbenko, D., Fennie, C., Rodriguez, H., Nguyen, T., Stachel, S. and Roseru, S. (1989) Cloning of a lymphocyte homing receptor reveals a lectin domain. Cell, 56, 1045-1055.
16. Lefer, D.J., Flynn, D.M., Phillips, M.L., Ratcliffe, M. and Buda, A.J. (1994) A novel sialyl Lewis x analog attenuates neutrophil accumulation and myocardial necrosis after ischemia and reperfusion. Circulation, 90, 2390-2401.
17. Li, S.H., Burns, D.K., Rumberger, J.M., Presky, D.H., Wilkinson, V.I., Anostario, M., Wolitzky, B.A., Norton, C.R., Farnilletti, P.C., Kim, K.J., Goldstein, A.L., Cox, D.C. and Huang, K. (1993) Consensus repeat domains of E-selectin enhance ligand binding. J. Biol. Chem., 269, 4431-4437
18. Ma, X.L , Tsao, P.S. and Lefer, A.M. (1991) Antibody to CD-18 exerts endothelial and cardiac protective effects in myocardial ischemia and reperfusion. J Clin Invest., 88, 1237-1243.
19. x moiety on rat polymorphortuclear leukocytes responsible for binding to rat E-selectin. Biochem. Biophys. Res. Commun., 215, 547-554.
20. Mulligan, M.S., Polley, M.J., Bayer, R.J., Nunn, M.F., Paulson, J.C. and Ward, P.A. (1992) Neutrophil dependent acute lung injury: requirement for P-selectin (GMP-140). J. Clin. Invest., 90, 1600-1607.
21. Mulligan, M.S., Paulson, J.C., Frees, S.D., Zheng, Z.L., Lowe, J.B and Ward, P.A. (1993) Protective effects of oligosaccharides in P-selectin-dependent lung injury. Nature, 364, 149-151.
22. Nagata, K., Tsuji, T., Todoroki, N., Katagiri, Y., Tanoue, K., Yamazaki, H., Hanai, N. and Irimura, T. (1993) Activated platelets induce superoxide anion release by monocytes and neutrophils through P-selecrin (CD62), J. Immunol., 151, 3267-3273.
23. Norton, C R., Rumberger, J.M., Burns, D.K and Wolitzky, B.A. (1993) Characterization of murine E-selectin expression in vitro using novel anti-mouse E-selectin monoclonal antibodies. Biochem. Biophys. Res Commun., 195, 250-258
24. Ohnishi, M., Koike, H., Kawamura, N., Tojo, S.J., Hayashi, M. and Morooka, S. (1996), Immunopharmacology, in press.
25. Oi, V.T. and Hertzenberg, L.A. (1980) Immunoglobulin-producing hybrid cell lines. In Mishel, B.B. and Shiigi, S.M. (eds.), Selected Methods in Cellular Immunologv Freeman, San Francisco, pp. 351-372.
26. Polley, M.J., Phillips, M.L., Wayner, E., Nudelman, A.K., Singhal, A.K., Hakomori, S.I. and Paulson, J.C. (1991) CD62 and endothelial cell leukocyte adhesion molecule-1 (ELAM-I) recognize the same carbohydrate ligand, sialyl-Lewis X. Proc. Natl. Acad. Sci. USA, 88, 6224-6228.
27. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
28. Sanders, E.W., Wilson, R.M. Ballantyne, C.M. and Beaudet, A.L. (1992) Molecular cloning and analysis of in vivo expression of murine P-selectin. Blood, 80, 795-799.
29. Simpson, P.J., Todd, R.F., Fantone, J.C., Mickelson, J.K., Griffin, J.D. and Lucchesi, B.R. (1988) Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mol, anti-CD11b) that inhibits leukocyte adhesion. J. Clin. Invest., 81, 624-629.
30. Takeda, I., Kaise, S., Nishimaki, T. and Kasukawa, R. (1994) Soluble P-selectin in the plasma of patients with connective tissue diseases. Int. Arch. Allergy Immunol., 105, 128-134.
31. Tamatani, T., Kuida, C., Watanabe, T., Koike, S. and Miyasaka, M. (1993) Molecular mechanisms underlying lymphocyte recirculation. III. Characterization of the LECAM-1 (L-selectin)-dependent adhesion pathway in rats. J. Immunol., 150, 1735-1745.
32. Tedder, T., Steeber, D., Chen, A. and Engel, P. (1995) The selectins: vascular adhesion molecules. FASEB J., 9, 866-873.
33. Towbin, H., Staehelin, T. and Gordon, J. (1979) Electrophoretic transfer of proteins from polyacrylamide gets to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA, 76, 4350-4354.
34. Tsuji, T., Nagata, K., Koike, J., Todoroki, N. and Irimura, T. (1994) Induction of superoxide anion production from monocytes and neutrophils by activated platelets through the P-selectin-sialyl Lewis X interaction. J. Leukocyte Biol., 56, 583-587.
35. Weller, A., Isenmann, S. and Vestweber, D. (1992) Cloning of the mouse endothelial selectins. Expression of both E- and P-selectin is inducible by tumor necrosis factor alpha. J. Biol. Chem., 267, 15176-15183.
36. Weyrich, A.S., Ma, X., Lefer, D.J., Albertine, K.H. and Lefer, A.M. (1993) In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury. J. Clin. Invest., 91, 2620-2629.
37. Weyrich, A.S , Buerke, M., Albertine, K.H. and Lefer, A.M. (1995a) Time course of coronary vascular endothelial adhesion molecule expression during reperfusion of the ischemic feline myocardium. J. Leukocyte Biol., 57, 45-55.
38. Weyrich, A.S., McIntyer, T.M., McEver, R.P., Prescott, S.M. and Zimmerman, G.A. (1995b) Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factor-α secretion. J. Clin. Invest., 95, 2297-2303.
39. Winn, R.K., Liggitt, D., Vedder, N.B., Paulson, J.C. and Harlan, J.M. (1993) Anti-P-selectin monoclonal antibody attenuates reperfusion injury to the rabbit ear. J. Clin Invest., 92, 2042-2047.
40. Yamazaki, T., Seko, Y., Tamatani, T., Miyasaka, M., Yagita, H., Okumura, K., Nagai, R. and Yazaki, Y. (1993) Expression of intercellular adhesion molecule-1 in rat heart with ischemia/reperfusion and limitation of infarct size by treatment with antibodies against cell adhesion molecules. Am. J. Pathol., 143, 410-418.
41. Yokota, S., Ohtsuka, H. and Noguchi, H. (1992) Monoclonal antibodies against Pseudomonas aeruginosa elastase; a neutralizing antibody which recognizes a conformational epitope related to an active site of elastase. Eur. J. Biochem., 206, 587-593.
42. Yokota, S., Nunn, M.F. and Morooka, S. (1996) Cross-linking of the ninth consensus repeat (CR9) domain of P-selectin (GMP-140, CD62P) with a monoclonal antibody enhanced leukocyte adhesive activity. Biochem. Biophys. Res. Commun., 218, 709-713.