Sequential adhesion of platelets and leukocytes from flowing whole blood onto a collagen-coated surface: Requirement for a GpVI-binding site in collagen

Thrombosis and Haemostasis

Volumn 97, Issue 5, 2007, Pages 814-821

  Butler, Lynn M ^a   Metson Scott, Tom ^a   Felix, Jo ^a   Abhyankar, Anita ^a   Rainger, G Ed ^a   Frandale, Richard W ^b   Watson, Stephen P ^a   Nash, Gerard B ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Adhesion; Collagen; Neutrophils; Platelet; Rheology

Indexed keywords

COLLAGEN; FLUORESCENT DYE; GLYCOPROTEIN VI; PADGEM PROTEIN;

ARTICLE; BINDING SITE; BLOOD FLOW; CAPILLARY; CELL INTERACTION; LEUKOCYTE ADHERENCE; PERFUSION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN MOTIF; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION;

ADULT; BINDING SITES; CELL ADHESION; COATED MATERIALS, BIOCOMPATIBLE; COLLAGEN; HEMORHEOLOGY; HUMANS; LEUKOCYTES; PLATELET ADHESIVENESS; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, COLLAGEN;

EID: 34249059297     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-08-0439     Document Type: Article

References (29)

1. Massberg S, Enders G, Matos FC, et al. Fibrinogen deposition at the postischemic vessel wall promotes platelet adhesion during ischemia-reperfusion in vivo. Blood 1999; 94: 3829-3838.
2. Massberg S, Brand K, Gruner S, et al. A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation. J Exp Med 2002; 196: 887-896.
3. Kuligowski MP, Kitching AR, Hickey MJ. Leukocyte recruitment to the inflamed glomerulus: a critical role for platelet-derived P-selectin in the absence of rolling. J Immunol 2006; 176: 6991-6999.
4. Andrews RK, Shen Y, Gardiner EE, et al. Platelet adhesion receptors and (patho)physiological thrombus formation. Histol Histopathol 2001; 16: 969-980.
5. Nieswandt B, Watson SP. Platelet-collagen interaction: is GPVI the central receptor? Blood 2003; 102: 449-461.
6. Siljander PR, Munnix IC, Smethurst PA, et al. Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood. Blood 2004; 103: 1333-1341.
7. Buttrum SM, Hatton R, Nash GB. Selectin-mediated rolling of neutrophils on immobilized platelets. Blood 1993; 82: 1165-1174.
8. Lalor P, Nash GB. Adhesion of flowing leucocytes to immobilized platelets. Br J Haematol 1995; 89: 725-732.
9. Stone PC, Nash GB. Conditions under which immobilized platelets activate as well as capture flowing neutrophils. Br J Haematol 1999; 105: 514-522.
10. Yeo EL, Sheppard JA, Feuerstein IA. Role of P-selectin and leukocyte activation in polymorphonuclear cell adhesion to surface adherent activated platelets under physiologic shear conditions (an injury vessel wall model). Blood 1994; 83: 2498-2507.
11. Ostrovsky L, King AJ, Bond S, et al. A juxtacrine mechanism for neutrophil adhesion on platelets involves platelet-activating factor and a selectin-dependent activation process. Blood 1998; 91: 3028-3036.
12. Rebello SS, Huang J, Lucchesi BR. Role of extracellular ionized calcium in the in vitro assessment of GpIIb/IIIa receptor antagonists. J Thromb Thrombolysis 2000; 9: 23-28.
13. Abbitt KB, Nash GB. Characteristics of leucocyte adhesion directly observed in flowing whole blood in vitro. Br J Haematol 2001; 112: 55-63.
14. Smethurst PA, Joutsi-Korhonen L, O'Connor MN, et al. Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood 2004; 103: 903-911.
15. Cooke BM, Usami S, Perry I, et al. A simplified method for culture of endothelial cells and analysis of adhesion of blood cells under conditions of flow. Microvasc Res 1993; 45: 33-45.
16. Knight CG, Morton LF, Onley DJ, et al. Collagen-platelet interaction: Gly-Pro-Hyp is uniquely specific for platelet Gp VI and mediates platelet activation by collagen. Cardiovasc Res 1999; 41: 450-457.
17. Bahra P, Nash GB. Sparsely adherent platelets support capture and immobilization of flowing neutrophils. J Lab Clin Med 1998; 132: 223-228.
18. Abbitt KB, Nash GB. Rheological properties of the blood influencing selectin-mediated adhesion of flowing leukocytes. Am J Physiol 2003; 285: H229-H240.
19. Abbitt KB, Rainger GE, Nash GB. Effects of fluorescent dyes on selectin and integrin-mediated stages of adhesion and migration of flowing leukocytes. J Immunol Methods 2000; 239: 109-119.
20. Smith E, Lally F, Cocker L, et al. Phototoxicity and fluorotoxicity combine to alter the behaviour of neutrophils in fluorescence microscopy based flow adhesion assays. Microsc Res Tech 2006; 69: 875-884.
21. Sheikh S, Nash GB. Continuous activation and deactivation of integrin CD11b/CD18 during de novo expression enables rolling neutrophils to immobilize on platelets. Blood 1996; 87: 5040-5050.
22. Pasquet JM, Gross B, Quek L, et al. LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI. Mol Cell Biol 1999; 19: 8326-8334.
23. Asselin J, Knight CG, Farridale RW, et al. Monomeric (glycine-proline-hydroxyproline)10 repeat sequence is a partial agonist of the platelet collagen receptor glycoprotein VI. Biochem J 1999; 339: 413-418.
24. Gibbins JM, Okuma M, Farndale R, et al. Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain. FEBS Lett 1997; 413: 255-259.
25. King MR, Heinrich V, Evans E, et al. Nano-to-Micro Scale Dynamics of P-Selectin Detachment from Leukocyte Interfaces. III. Numerical Simulation of Tethering under Flow. Biophys J 2005; 88: 1676-1683.
26. von Hundelshausen P, Weber KS, Huo Y, et al. RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium. Circulation 2001; 103: 1772-1777.
27. Nash GB, Morland C, Sheikh S, et al. Adhesion between leucocytes and platelets:rheology, mechanisms and consequences. In: Progress in Applied Microcirculation, S. Karger 1996; 98-113.
28. Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 1991; 65: 859-873.
29. Skilbeck CA, Walker PG, David T, et al. Disturbed flow promotes deposition of leucocytes from flowing whole blood in a model of a damaged vessel wall. Br J Haematol 2004; 126: 418-427.