Number of women needed in a prospective trial to prove potential cardiovascular benefit of hormone replacement therapy

Climacteric

Volumn 10, Issue 3, 2007, Pages 238-243

  Depypere, H T ^a   Tummers, P ^a   De Bacquer, D ^a   De Backer, G ^a   Do, M ^a   Dhont, M ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Cardiovascular benefit; Hormone replacement therapy; Prospective trial

Indexed keywords

HORMONE;

ARTICLE; BELGIUM; DATA BASE; FEASIBILITY STUDY; HEART PROTECTION; HORMONE SUBSTITUTION; METHODOLOGY; MORTALITY; PATIENT SELECTION; POPULATION DYNAMICS; POSTMENOPAUSE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SAMPLING;

ADULT; AGED; BELGIUM; CARDIOVASCULAR DISEASES; DATABASES, FACTUAL; ESTROGEN REPLACEMENT THERAPY; FEMALE; HUMANS; MIDDLE AGED; PATIENT SELECTION; POSTMENOPAUSE; PROSPECTIVE STUDIES;

EID: 34248597560     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.1080/13697130701344786     Document Type: Article

References (31)

1. Hulley S, Furburg C, Barrett-Connor E, et al. HERS Research Group. Vascular disease outcomes during 6.8 years of hormone therapy. JAMA 2002;288:58-66
2. Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). JAMA 2002;288:49-57
3. Writing Group for the Women's Health Initiative. Principal results form the Women's Health Initiative randomized controlled trial. JAMA 2002;288:321-333
4. Anderson GL, Limacher M, Assaf AR, et al. Women's Health Initiative Steering Committee. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy. The Women's Health Initiative randomized controlled trial. JAMA 2004;291:1701-12
5. Stampfer MJ, Colditz GA, Willett WC, et al. Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the Nurses' Health Study. N Engl J Med 1991;325:756-62
6. Grodstein F, Stampfer M, Colditz G, et al. Postmenopausal hormone therapy and mortality. N Engl J Med 1997;336:1769-75
7. Clarkson TB. The new conundrum: do estrogens have any cardiovascular benefits? Int J Fertil 2002;47:61-8
8. Stampfer M, Colditz G. Estrogen replacement therapy and coronary disease: a quantitative assessment of the epidemiologic evidence. Prev Med 1991;20:47-63
9. Hu F, Stampfer M, Manson J, et al. Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women. N Engl J Med 2000;343:530-7
10. Manson JE, Hsia J, Johnson KC, et al. Estrogen plus progestin and the risk of coronary heart disease. N Engl J Med 2003;349:523-34
11. Naftolin F, Taylor H, Karas R, et al. The Women's Health Initiative could not have detected cardioprotective effects of starting hormone therapy during the menopausal transition. Fertil Steril 2004;81:1498-501
12. Bath Ph, Gray L. Association between hormone replacement therapy and subsequent stroke: a meta-analysis. BMJ 2005;330:342-4
13. International Menopause Society Executive Committee. Guidelines for the hormone treatment of women in the menopausal transition and beyond: Position Statement by the Executive Committee of the International Menopause Society. Climacteric 2004;7:8-11
14. Hsia J, Langer RD, Manson JE, et al. for the Women's Health Initiative Investigators. Conjugated equine estrogens and coronary heart disease. Arch Intern Med 2006;166:357-65
15. Salpeter S, Walsh J, Greyber E, et al. Mortality associated with hormone replacement therapy in younger and older women. J Gen Intern Med 2004;19:791-804
16. De Backer G. Nutrition and health: an interuniversity study. Regional differences in dietary habits, coronary risk factors and mortality rates in Belgium. I. Design and methodology. Acta Cardiol 1984;39:285-92
17. WHO-MONICA Project Principal Investigators. The World Health Organisation MONICA project (Monitoring Trends and Determinants in Cardiovascular Disease): a major international collaboration. J Clin Epidemiol 1988;41:105-14
18. Houtman I, Kornitzer M, De Smet P, et al. Job stress, absenteeism and coronary heart disease: European cooperative study (the JACE study). Design of a multicentre prospective study. Eur J Publ Health 1999;9:52-7
19. De Backer G, De Bacquer D, Brohet C, et al. Guidelines on cardiovascular disease prevention in clinical practice. Rev Med Liege 2005;60:163-72
20. Braunwald E. Shattuck Lecture - cardiovascular medicine at the turn of the millennium: triumphs, concerns and opportunities. N Engl J Med 1997;337:1360-9
21. Machin D, Campell MJ, Fayers P, Pinol A. Statistical Tables for the Design of Clinical Studies, 2nd edn. Oxford: Blackwell Publications, 1997
22. Tunstall-Pedoe H. Myth and paradox of coronary risk and menopause. Lancet 1998;351:1425-7
23. Raza JA, Reinhart R, Mohaved A. Ischemic heart disease in women and the role of hormone therapy. Int J Cardiol 2004;96:7-19
24. Andersen K, Launer L, Dewey M, et al. for the EURODEM Incidence Research Group. Gender differences in the incidence of AD and vascular dementia: the EURODEM studies. Neurology 1999;53:1992-7
25. Zandi P, Carlson M, Plassman B, et al. Hormone replacement therapy and incidence of Alzheimer disease in older women. JAMA 2002;288:2123-9
26. Espeland M, Rapp S, Shumaker S, et al. Conjugated equine estrogens and global cognitive function in postmenopausal women. JAMA 2004;291:2959-68
27. Prestwood KM, Kenny AM, Kleppinger A, et al. Ultralow-dose micronized 17 beta estradiol and bone density and bone metabolism in older women: a randomized controlled trial. JAMA 2003;290:1042-8
28. Viscoli C, Brass L, Kernan W, et al. A clinical trial of estrogen-replacement therapy after ischemic stroke. N Engl J Med 2001;345:1243-9
29. Hodis H, Mack W, Lobo R. Estrogen in the prevention of atherosclerosis. Ann Intern Med 2001;135:939-53
30. Hodis H, Wendy J, Azen S, et al. Hormone therapy and the progression of coronary-artery atherosclerosis in postmenopausal women. N Engl J Med 2003;349:535-45
31. Grodstein F, Manson J, Colditz G, et al. A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med 2000;133:933-41