Effects of antisense oligodeoxynucleotides on Nogo-A mRNA expression in injured optic nerves

International Journal of Ophthalmology

Volumn 7, Issue 2, 2007, Pages 354-356

  Yuan, Rong Di ^a   Ye, Jian ^a   Peng, Xi Jia ^a   Liu, Shao Zhang ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antisense oligodeoxynucleotides; Injury; Nogo A; Optic nerve; Reverse transcriptase polymerase chain reaction

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; MESSENGER RNA; PROTEIN NOGO A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; NONHUMAN; OPTIC NERVE INJURY; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS;

EID: 34248593199     PISSN: 16725123     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Chen MS, Huber AB, van der Haar Me, Frank M, Schnell L, Spillmann AA, Christ F, Schwab ME. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature,2000;403:434-439
2. Prinjha R,Moore SE,Christie G, Vinson M, Blake S, Morrow R, Michalovich D, Simmons DL, Walsh FS. Inhibitor of neurite outgrowth in humans. Nature,2000; 403:383-384
3. GrandPr T, Nakamura F, Vartanian T, Strittmatter SM. Identification of the Nogo inhibitor of axon regeneration as a Reticulon protein. Nature,2000;403:439-444
4. Chinese source.
5. Rubin BP, Dusart I, Schwab ME. A monoclonal antibody (IN-1) which neutralizes neurite growth inhibitory proteins in the rat CNS recognizes antigens localized in CNS myelin. J Neurocytol,1994;23:209-217
6. Brosamle C, Huber AB, Fiedler M, Skerra A, Schwab ME. Regeneration of lesioned corticospinal tract fibers in the adult rat induced by a recombinant, humanized IN-1 antibody fragment. J Neurosci,2000; 20:8061-8068
7. Fournier AE, GrandPre T, Strittmatter SM. Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration. Nature.2001; 409:341-346
8. Huher AB, Schwab ME. Nogo-A, a potent inhibitor of neurite outgrowth and regeneration. Biol Chem,2000; 381:407-419
9. Goldberg JL, Barres BA. Nogo in nerve regeneration. Nature,2000; 403:369-370
10. Schnell L, Schwab ME. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors. Nature,1990; 343:269-272
11. Buffo A, Zagrebelsky M, Huber AB. Application of neutralizing antibodies against NI-35/250 myelin-associated neurite growth inhibitory proteins to the adult rat cerebellum induces sprouting of uninjured purkinje cell axons. J Neurosci, 2000;20:2275-2286
12. Wang S, Lee HJ, Cauchon D. Delivery of antisense oligodeoxyibonucleotides against the human epidermal growth factor receptor into cultured Kbcells with liposomes conjugated to folate via polyethyleneglycol. Proc Natl Acad Sci USA,1995, 92: 3318-3322
13. Tari AM, Lopez-Berestein G. Cellular uptake of antisense oligonucleotides. Curr Opin Investig Drugs,2001;2:1450-1453