Inhibition of Na+ and Ca2+ reabsorption by P2u purinoceptors requires PKC but not Ca2+ signaling

American Journal of Physiology

Volumn 270, Issue 1 PART 2, 1996, Pages

  Koster, Henk P G ^a   Hartog, Anita ^a   Van Carel, H O S ^a   Bindels, René J M ^a  

^a RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

Author keywords

Adenosine triphosphate; Connecting tubule; Cortical collecting duct; Cortical collecting system; Purinergic receptor; Sodium channel

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; PROTEIN KINASE C; PURINE RECEPTOR; SODIUM; PURINE P2 RECEPTOR; SODIUM CHANNEL;

ABSORPTION; ANIMAL; ARTICLE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; EXTRACELLULAR SPACE; INTRACELLULAR MEMBRANE; KIDNEY COLLECTING TUBULE; METABOLISM; OSMOLARITY; PHYSIOLOGY; RABBIT; SIGNAL TRANSDUCTION; ANIMAL CELL; CALCIUM ABSORPTION; CALCIUM TRANSPORT; ENZYME ACTIVITY; KIDNEY PROXIMAL TUBULE; NONHUMAN; PRIORITY JOURNAL; SODIUM ABSORPTION; SODIUM TRANSPORT;

ABSORPTION; ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELLS, CULTURED; ENZYME ACTIVATION; EXTRACELLULAR SPACE; INTRACELLULAR MEMBRANES; KIDNEY TUBULES, COLLECTING; OSMOLAR CONCENTRATION; PROTEIN KINASE C; RABBITS; RECEPTORS, PURINERGIC; SIGNAL TRANSDUCTION; SODIUM;

EID: 0030063378     PISSN: 00029513     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajprenal.1996.270.1.f53     Document Type: Article

References (24)

1. Anderson, R. J., R. Breckon, and B. S. Dixon. ATP receptor regulation of adenylate cyclase and protein kinase C activity in cultured renal LLC-PK1 cells. J. Clin. Invest. 87: 1732-1738, 1991.
2. Bindels, R. J. M. Calcium handling by the mammalian kidney. J. Exp. Biol. 184: 89-104, 1993.
3. Bindels, R. J. M., J. A. Dempster, P. L. M. Ramakers, P. G. H. M. Willems, and C. H. van Os. Effect of protein kinase C activation and down-regulation on active calcium transport across rabbit renal collecting system. Kidney Int. 43: 295-300, 1993.
4. Bindels, R. J. M., A. Hartog, S. L. Abrahamse, and C. H. van Os. Effects of pH on apical calcium entry and active calcium transport in rabbit cortical collecting system. Am. J. Physiol. 266(Renal Fluid Electrolyte Physiol. 35): F620-F627, 1994.
5. Bindels, R. J. M., A. Hartog, J. Timmermans, and C. H. van Os. Active Ca2+ transport in primary cultures of rabbit kidney CCD: stimulation by 1,25-dihydroxyvitamin DS and PTH. Am. J. Physiol. 261(Renal Fluid Electrolyte Physiol. 30): F799-F807, 1991.
6. 2+ transport across primary cultures of rabbit kidney collecting system. Pfluegers Arch. 420: 566-572, 1992.
7. Breyer, M. D., and Y. Ando. Hormonal signaling and regulation of salt and water transport in the collecting duct. Annu. Rev. Physiol. 56: 711-739,1994.
8. Cejka, J. C., M. Bidet, M. Taue, and P. Poujeol. Nucleotides mobilize intracellular calcium stores of renal proximal cells in primary culture: existence of a suramin-sensitive mechanism. Biochim. Biophys. Acta 1176: 7-12, 1993.
9. Dekker, L. V., and P. J. Parker. Protein kinase C: a question of specificity. Trends Biol. Sci. 19: 73-77, 1994.
10. Dubyak, G. R., and C. El-Moatassim. Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides.Ara. J. Physiol. 265(Cell Physiol. 34): C577-C606,1993.
11. Elmoatassim, C., J. Dornand, and J. C. Mani. Extracellular ATP and cell signalling. Biochim. Biophys. Acta 1134: 31-45, 1992.
12. Feher, J. J., C. S. Fullmer, and R. H. Wasserman. Role of facilitated diffusion of calcium by calbindin in intestinal calcium absorption. Am. J. Physiol. 262(Cell Physiol. 31): C517-C526, 1992.
13. Frindt, G., and E. E. Windhager. Ca2+-dependent inhibition of sodium transport in rabbit cortical collecting tubules. Am. J. Physiol. 258(Renal Fluid Electrolyte Physiol. 27): F568-F582, 1990.
14. Inscho, E. W., K. D. Mitchell, and L. G. Navar. Extracellular ATP in the regulation of renal microvascular function. FASEB J. 8: 319-328, 1994.
15. Koster, H. P. G., C. H. van Os, and R. J. M. Bindels. Ca2 + oscillations in cells from the rabbit renal cortical collecting system induced by Na+-free solutions. Kidney Int. 43: 828-836, 1993.
16. Ling, B. N., K. E. Kokko, and D. C Eaton. Inhibition of apical Na+ channels in rabbit cortical collecting tubules by basolateral prostaglandin-Ej is modulated by protein kinase C. J. Clin. Invest. 90: 1328-1334,1992.
17. Lustig, K. D., K. D. Shiau, A. J. Brake, and D. Julius. Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc. Natl. Acad. Sci. USA 90: 5113-5117,1993.
18. Middleton, J. P., A. W. Mangel, S. Basavappa, and J. G. Fitz. Nucleotide receptors regulate membrane ion transport in renal epithelial cells. Am. J. Physiol. 264(Renal Fluid Electrolyte Physiol. 33): F867-F873,1993.
19. Olsson, R. A., and J. D. Pearson. Cardiovascular purinoceptors. Physiol. Rev. 70: 761-845,1990.
20. Palmer, L. G., and G. Frindt. Effects of cell Ca and pH on Na channels from rat cortical collecting tubule. Am. J. Physiol. 253(Renal Fluid Electrolyte Physiol. 22): F333-F339, 1987.
21. Paulmichl, M., and F. Lang. Enhancement of intracellular calcium concentration by extracellular ATP and UTP in Madin Darby canine kidney cells. Biochem. Biophys. Res. Commun. 156: 1139-1143,1988.
22. Pfeilschifter, J., and C. Merriweather. Extracellular ATP and UTP activation of phospholipase-D is mediated by protein kinase c-e in rat renal mesangial cells. Br. J. Pharmacol. 110: 847-853, 1993.
23. Rouse, D., M. Leite, and W. N. Suki. ATP inhibits the hydrosmotic effect of AVP in rabbit CCT: evidence for a nucleotide P2u receptor. Am. J. Physiol. 267(Renal Fluid Electrolyte Physiol. 36): F289-F295,1994.
24. Snedecor, G. W., and W. G. Cochran. Statistical Methods. Ames: Iowa State University, 1974.