Dry powder inhalers: Challenges and goals for next generation therapies

Pharmaceutical Technology Europe

Volumn 19, Issue 4, 2007, Pages 19-24

  Chan, Hak Kim ^a   Young, Paul M ^a   Traini, Daniela ^a   Coates, Matthew ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LACTOSE; LEUCINE; MAGNESIUM; MANNITOL; MOMETASONE FUROATE; STEARIC ACID;

AEROSOL; ARTICLE; ASTHMA; ATOMIC FORCE MICROSCOPY; CRYSTALLIZATION; DRUG APPROVAL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG MARKETING; DRUG STABILITY; DRY POWDER; EQUIPMENT DESIGN; INHALER; INSPIRATORY CAPACITY; INTERMETHOD COMPARISON; PARTICLE SIZE; SURFACE PROPERTY;

EID: 34248392550     PISSN: 01646826     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (52)

1. I.J. Smith and M. Parry-Billings, Pulm. Pharmacol. Therapeut., 16(2), 79-95 (2003).
2. B.K. Rubin, Paediat. Respir. Rev., 7(Supplement 1), S76-S79 (2006).
3. J.S. Patton, J. Bukar and S. Nagarajan, Adv. Drug Deliv. Rev., 35(2-3), 235-247 (1999).
4. A.L. Smith, J. Cystic Fibrosis, 1(Supplement 2), 189-193 (2002).
5. H.K. Chan and I. Gonda, J. Pharmaceut Sci., 78, 176-180 (1989)
6. H.K. Chan and I. Gonda, J. Aerosol Sci., 20, 157-165 (1989).
7. H.K. Chan and I. Gonda, J. Pharmaceut. Sci., 84, 692-696 (1995).
8. A.J. Hickey and T.B. Martonen, Pharmaceut. Res., 10, 1-7 (1993).
9. A.J. Hickey et al., J. Pharmaceut. Sci., 79, 1009-1014 (1990).
10. H.K. Chan, J. Aerosol Med., 19, 21-27 (2006).
11. H.K. Chan, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 284, 50-55 (2006).
12. H.K. Chan and N.Y.K. Chew, Adv. Drug Deliv. Rev., 55(7), 793-805 (2003).
13. I. Pasquali, R. Bettini and F. Giordano, J. Pharmaceut. Science, 2(4), 299-310 (2006).
14. J.N. Staniforth, Aerosol Sci. Tech., 22, 346-353 (995).
15. Y. Kawashima et al., Int. J. Pharmaceutics, 172, 179-188 (1998).
16. X.M. Zeng et al., J. Pharm. Pharmacol., 52, 1211-1221 (2000).
17. X.M. Zeng et al., Int. J. Pharmaceutics, 200, 93-106 (2000).
18. P. Lucas, K. Anderson and J.N. Staniforth, Pharmaceut. Res., 15, 562-569 (1998).
19. N. Islam et al., Pharmaceut. Res., 21, 492-499 (2004).
20. H. Steckel et al., Int. J. Pharmaceutics, 309, 51-59 (2006).
21. N. Islam et al., J. Pharmaceut Sci., 93, 1030-1038 (2004).
22. A.H. de Boer et al., Int. J. Pharmaceutics, 294, 173-184 (2005).
23. P.M. Young, Int. J. Pharmaceutics, 296, 26-33 (2005).
24. X.M. Zeng et al., Eur. J. Pharm. Biopharm., 51, 55-62 (2001).
25. F. Ferrari et al., AAPS PharmSciTech., 5, 1-6 (2004).
26. P.M. Young et al., J. Pharm. Pharmacol., 54, 1339-1344 (2002).
27. D. EI-Sabawi et al., Drug Dev. Ind. Pharm., 32, 243-251 (2006).
28. P. Lucas et al., Pharmaceut. Res., 16, 1643-1647 (1999).
29. M.D. Louey and P.J. Stewart, Pharmaceut. Res., 19, 1524-1531 (2002).
30. T. Yang and D. Kenyon, "Use of an Agglomerate Formulation in a New Multidose Dry Powder Inhaler", in R. Dalby et al., Eds, Respiratory Drug Delivery Volume II (Davis Horwood International, UK, 2002), pp 503-506.
31. B. Fan, T. Yang and D. Kenyon, "Application of Computer Modeling in the Design and Development of the New Mometasone Furoate Dry Powder Inhaler (MF-DPI) Nozzle", in R. Dalby et al., Eds, Respiratory Drug Delivery VII, (Davis Horwood International, UK, 2002), pp 491-494.
32. M. Wedel and B. Frynrs, "Simulated In-use Performance of Sofotec's Dry Powder Inhaler, the Novolizer", in R. Dalby et al., Eds, Respiratory Drug Delivery IX, (Davis Horwood International, UK, 2004), pp 689-692.
33. A.H. de Boer et al., Int. J. Pharmaceutics, 260, 187-200 (2003).
34. G. Brambilla et al, "Designing a Novel Dry Powder Inhaler: The Next DPI", in R. Dalby et al., Eds, Respiratory Drug Delivery X, (Davis Horwood International, UK, 2006), pp 553-556.
35. C. Yamashita, K. Manabe and Y. Fukunaga, "A Novel Otsuka Dry Powder Inhalation (ODPI) System for Proteins and Peptides", in R. Dalby et al., Eds, Respiratory Drug Delivery IX (Davis Horwood International, UK, 2004), pp 593-596.
36. D. Gardner and R. Casper, "Development of a Novel Dry Powder Inhaler", in R. Dalby et al., Eds, Respiratory Drug Delivery IX (Davis Horwood International, UK, 2004), pp 661-664.
37. T. Crowder, S. Johnson and C. Boyce, "A Novel Platform Delivery System for Combination Respiratory Therapies", in R. Dalby et al., Eds, Respiratory Drug Delivery VII (Davis Horwood International, UK, 2006), pp 725-728.
38. J. Zhu and Y. Ma, "A New Breath-activated, Excipient-free Dry Powder Inhaler and a Rotating Fluidized Bed Powder Dispenser for Pulmonary Drug Delivery", in R. Dalby et al., Eds, Respiratory Drug Delivery VII (Davis Horwood International, UK, 2006), pp 925-930.
39. P.M. Young et al., J. Aerosol Med., 17(2), 123-128 (2004).
40. M.S. Coates et al., J. Pharmaceut. Sci., 93, 2863-2876 (2004).
41. M.S. Coates, D.F. Fletcher and J.A. Raper, J. Pharmaceut. Sci., 95, 1382-1392 (2006).
42. M.S. Coates et al., Pharmaceut. Res., 22, 1445-1453 (2005).
43. M.S. Coates et al., Pharmaceut. Res., 22, 923-932 (2005).
44. J.A. Schuster et al., Pharmaceut. Res., 14, 354-357 (1997).
45. J.A. Schuster et al., "Design and performance validation of highly efficient and reproducible compact aerosol delivery system: AERx", in R.N. Dalby et al., Eds, Respiratory Drug Delivery VI, (Interpharm Press, Buffalo Grove, IL, USA, 1996), pp 83-90.
46. W.C. Zimlich et al., "The development of a novel electrohydrodynamic (EHD) pulmonary drug delivery device", in R.N. Dalby et al., Eds, Respiratory Drug Delivery VII, Volume I, (Serentec Press, Raleigh, NC, USA, 2000), pp 241-246.
47. R. Gupta, Aerosol Sci. Tech., 37, 672-681 (2003).
48. J.N. Hong et al., J. Aerosol Med., 15, 359-368 (2002).
49. L.R. De Young et al., "The AeroDose multidose inhaler device and delivery characteristics", in R.N. Dalby, P.R. Byron and S.J. Farr, Eds, Respiratory Drug Delivery VI (Interpharm Press, Buffalo Grove, IL, USA, 1998), pp 91-96.
50. B. Zierenberg, "Development of the BiNeb (Respimat prototype) novel liquid metering inhaler", in R.N. Dalby. P.R. Byron and S.J. Farr, Eds, Respiratory Drug Delivery V (Interpharm Press, Buffalo Grove, IL, USA, 1996), pp 187-199.
51. P.H. Hirst et al., "Deposition, absorption and bioavailability of aerosolized morphine sulfate delivered by a hand held device, the Metered Solution Inhaler (MSI)", in R.N. Dalby et al., Eds, Respiratory Drug Delivery VII, Volume II, (Serentec Press, Raleigh, NC, USA, 2000), pp 467-470.
52. P. Noymer et al., "AERx Essence: efficiency and breath control without electronics", in R.N. Dalby et al., Eds, Respiratory Drug Delivery IX Volume I (Virginia Commonwealth University, Richmond, VA, USA, 2004), pp 255-262.