-
1
-
-
0036031826
-
Epidemiology of colorectal cancer
-
Boyle P, Leon ME. Epidemiology of colorectal cancer. Br Med Bull 2002; 64: 1-25.
-
(2002)
Br Med Bull
, vol.64
, pp. 1-25
-
-
Boyle, P.1
Leon, M.E.2
-
2
-
-
0036033274
-
Genetics of colorectal cancer: Hereditary aspects and overview of colorectal tumorigenesis
-
Fearnhead NS, Wilding JL, Bodmer WF. Genetics of colorectal cancer: hereditary aspects and overview of colorectal tumorigenesis. Br Med Bull 2002; 64: 27-43.
-
(2002)
Br Med Bull
, vol.64
, pp. 27-43
-
-
Fearnhead, N.S.1
Wilding, J.L.2
Bodmer, W.F.3
-
3
-
-
7644228433
-
CpG island methylation in gastroenterologic neoplasia: A maturing field
-
Rashid A, Issa JP. CpG island methylation in gastroenterologic neoplasia: a maturing field. Gastroenterology 2004; 127: 1578-88.
-
(2004)
Gastroenterology
, vol.127
, pp. 1578-1588
-
-
Rashid, A.1
Issa, J.P.2
-
4
-
-
0029022018
-
Mutations of ras genes in human tumours
-
Kiaris H, Spandidos DA. Mutations of ras genes in human tumours. Int J Oncol 1995; 7: 413-21.
-
(1995)
Int J Oncol
, vol.7
, pp. 413-421
-
-
Kiaris, H.1
Spandidos, D.A.2
-
5
-
-
0030855153
-
Expression of ras proto-oncogenes: Regulation and implications in the development of human tumors
-
Zachos G, Spandidos DA. Expression of ras proto-oncogenes: regulation and implications in the development of human tumors. Crit Rev Oncol Hematol 1997; 26: 65-75.
-
(1997)
Crit Rev Oncol Hematol
, vol.26
, pp. 65-75
-
-
Zachos, G.1
Spandidos, D.A.2
-
6
-
-
0033168902
-
K-ras mutation and loss of heterozygosity of the adenomatous polyposis coli gene in patients with colorectal adenomas with in situ carcinoma
-
Zauber NP, Sabbath-Solitare M, Marotta SP, Bishop DT. K-ras mutation and loss of heterozygosity of the adenomatous polyposis coli gene in patients with colorectal adenomas with in situ carcinoma. Cancer 1999; 86: 31-6.
-
(1999)
Cancer
, vol.86
, pp. 31-36
-
-
Zauber, N.P.1
Sabbath-Solitare, M.2
Marotta, S.P.3
Bishop, D.T.4
-
8
-
-
0023748414
-
Genetic alterations during colorectal-tumor development
-
Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988; 319: 525-32.
-
(1988)
N Engl J Med
, vol.319
, pp. 525-532
-
-
Vogelstein, B.1
Fearon, E.R.2
Hamilton, S.R.3
-
10
-
-
0034667593
-
Meaningful relationships: The regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
-
Kolch W. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions. Biochem J 2000; 351: 289-305.
-
(2000)
Biochem J
, vol.351
, pp. 289-305
-
-
Kolch, W.1
-
11
-
-
0034762203
-
The Raf/MEK/ERK pathway: New concepts of activation
-
Peyssonnaux C, Eychene A. The Raf/MEK/ERK pathway: new concepts of activation. Biol Cell 2001; 93: 53-62.
-
(2001)
Biol Cell
, vol.93
, pp. 53-62
-
-
Peyssonnaux, C.1
Eychene, A.2
-
12
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417: 949-54.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
13
-
-
9644268152
-
BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level
-
Helmke BM, Mollenhauer J, Herold-Mende C, et al. BRAF mutations distinguish anorectal from cutaneous melanoma at the molecular level. Gastroenterology 2004; 127: 1815-20.
-
(2004)
Gastroenterology
, vol.127
, pp. 1815-1820
-
-
Helmke, B.M.1
Mollenhauer, J.2
Herold-Mende, C.3
-
15
-
-
0037194728
-
Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status
-
Rajagopalan H, Bardelli A, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature 2002; 418: 934.
-
(2002)
Nature
, vol.418
, pp. 934
-
-
Rajagopalan, H.1
Bardelli, A.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
Velculescu, V.E.6
-
16
-
-
0037112438
-
Similarity of the phenotypic patterns associated with BRAF and K-RAS mutations in colorectal neoplasia
-
Yuen ST, Davies H, Chan TL, et al. Similarity of the phenotypic patterns associated with BRAF and K-RAS mutations in colorectal neoplasia. Cancer Res 2002; 62: 6451-5.
-
(2002)
Cancer Res
, vol.62
, pp. 6451-6455
-
-
Yuen, S.T.1
Davies, H.2
Chan, T.L.3
-
17
-
-
0344253533
-
Staging of colon cancer
-
Lineweaver W. Staging of colon cancer. Contemp Surg 1984; 25: 19.
-
(1984)
Contemp Surg
, vol.25
, pp. 19
-
-
Lineweaver, W.1
-
18
-
-
0031690152
-
Activation of the ras genes in malignant and premalignant colorectal tumors
-
Glarakis IS, Savva S, Spandidos DA. Activation of the ras genes in malignant and premalignant colorectal tumors. Oncol Rep 1998; 5: 1451-4.
-
(1998)
Oncol Rep
, vol.5
, pp. 1451-1454
-
-
Glarakis, I.S.1
Savva, S.2
Spandidos, D.A.3
-
19
-
-
4043104159
-
Real-time allele-specific amplification for sensitive detection of the BRAF mutation V600E
-
Jarry A, Masson D, Cassagnau E, Parois S, Laboisse C, Denis MG. Real-time allele-specific amplification for sensitive detection of the BRAF mutation V600E. Mol Cell Probes 2004; 18: 349-52.
-
(2004)
Mol Cell Probes
, vol.18
, pp. 349-352
-
-
Jarry, A.1
Masson, D.2
Cassagnau, E.3
Parois, S.4
Laboisse, C.5
Denis, M.G.6
-
20
-
-
32044455746
-
BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status
-
Li WQ, Kawakami K, Ruszkiewicz A, Bennett G, Moore J, lacopetta B. BRAF mutations are associated with distinctive clinical, pathological and molecular features of colorectal cancer independently of microsatellite instability status. Mol Cancer 2006; 5: 2.
-
(2006)
Mol Cancer
, vol.5
, pp. 2
-
-
Li, W.Q.1
Kawakami, K.2
Ruszkiewicz, A.3
Bennett, G.4
Moore, J.5
lacopetta, B.6
-
21
-
-
0141593677
-
BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair
-
Wang L, Cunningham JM, Winters JL, et al. BRAF mutations in colon cancer are not likely attributable to defective DNA mismatch repair. Cancer Res 2003; 63: 5209-12.
-
(2003)
Cancer Res
, vol.63
, pp. 5209-5212
-
-
Wang, L.1
Cunningham, J.M.2
Winters, J.L.3
-
22
-
-
20344365798
-
BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms
-
Ikehara N, Semba S, Sakashita M, Aoyama N, Kasuga M, Yokozaki H. BRAF mutation associated with dysregulation of apoptosis in human colorectal neoplasms. Int J Cancer 2005; 20: 115: 943-50.
-
(2005)
Int J Cancer
, vol.20
, Issue.115
, pp. 943-950
-
-
Ikehara, N.1
Semba, S.2
Sakashita, M.3
Aoyama, N.4
Kasuga, M.5
Yokozaki, H.6
-
23
-
-
10044269883
-
Absence of mutations of BRAF gene in malignant melanoma of soft parts (clear cell sarcoma of tendons and aponeuroses)
-
Panagopoulos I, Mertens F, Isaksson M, Mandhal N. Absence of mutations of BRAF gene in malignant melanoma of soft parts (clear cell sarcoma of tendons and aponeuroses). Cancer Genet Cytogenet 2005; 156: 74-6.
-
(2005)
Cancer Genet Cytogenet
, vol.156
, pp. 74-76
-
-
Panagopoulos, I.1
Mertens, F.2
Isaksson, M.3
Mandhal, N.4
-
24
-
-
0037222652
-
Absence of exon 15 BRAF germline mutations in familial melanoma
-
Lang J, Boxer M, MacKie R. Absence of exon 15 BRAF germline mutations in familial melanoma. Hum Mutat 2003; 21: 327-30.
-
(2003)
Hum Mutat
, vol.21
, pp. 327-330
-
-
Lang, J.1
Boxer, M.2
MacKie, R.3
-
25
-
-
11144357649
-
Absence of BRAF mutations in UV-protected mucosal melanomas
-
Edwards RH, Ward MR, Wu H, et al. Absence of BRAF mutations in UV-protected mucosal melanomas. J Med Genet 2004; 41: 270-2.
-
(2004)
J Med Genet
, vol.41
, pp. 270-272
-
-
Edwards, R.H.1
Ward, M.R.2
Wu, H.3
-
26
-
-
0035444798
-
Kirsten ras mutations in patients with colorectal cancer: The 'RAS-CAL II' study
-
Andreyev HJ, Norman AR, Cunningham D, et al. Kirsten ras mutations in patients with colorectal cancer: the 'RAS-CAL II' study. Br J Cancer 2001; 85: 692-6.
-
(2001)
Br J Cancer
, vol.85
, pp. 692-696
-
-
Andreyev, H.J.1
Norman, A.R.2
Cunningham, D.3
-
27
-
-
0030703629
-
Colorectal carcinoma in Hong Kong: Epidemiology and genetic mutations
-
Yuen ST, Chung LP, Leung SY, et al. Colorectal carcinoma in Hong Kong: epidemiology and genetic mutations. Br J Cancer 1997; 76: 1610-6.
-
(1997)
Br J Cancer
, vol.76
, pp. 1610-1616
-
-
Yuen, S.T.1
Chung, L.P.2
Leung, S.Y.3
-
28
-
-
0023256456
-
Prevalence of ras gene mutations in human colorectal cancers
-
Bos JL, Fearon ER, Hamilton SR, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987; 327: 293-7.
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
-
29
-
-
0033739215
-
Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study
-
Samowitz WS, Curtin K, Schaffer D, Robertson M, Leppert M, Slattery ML. Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol Biomarkers Prev 2000; 9: 1193-7.
-
(2000)
Cancer Epidemiol Biomarkers Prev
, vol.9
, pp. 1193-1197
-
-
Samowitz, W.S.1
Curtin, K.2
Schaffer, D.3
Robertson, M.4
Leppert, M.5
Slattery, M.L.6
-
30
-
-
0036739336
-
Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype
-
Bazan V, Migliavacca M, Zanna I, et al. Specific codon 13 K-ras mutations are predictive of clinical outcome in colorectal cancer patients, whereas codon 12 K-ras mutations are associated with mucinous histotype. Ann Oncol 2002; 13: 1438-46.
-
(2002)
Ann Oncol
, vol.13
, pp. 1438-1446
-
-
Bazan, V.1
Migliavacca, M.2
Zanna, I.3
-
31
-
-
1942518932
-
Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer
-
Arun C, London NJM, Hemingway DM. Prognostic significance of elevated endothelin-1 levels in patients with colorectal cancer. Int J Biol Markers 2004; 19: 32-7.
-
(2004)
Int J Biol Markers
, vol.19
, pp. 32-37
-
-
Arun, C.1
London, N.J.M.2
Hemingway, D.M.3
-
32
-
-
0031017268
-
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
-
Kane MF, Loda M, Gaida GM, et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res 1997; 57: 808-11.
-
(1997)
Cancer Res
, vol.57
, pp. 808-811
-
-
Kane, M.F.1
Loda, M.2
Gaida, G.M.3
-
33
-
-
33749063204
-
Senescence and serration: A new twist to an old tale
-
Minoo P, Jass JR. Senescence and serration: a new twist to an old tale. J Pathol. 2006; 210(2): 137-40.
-
(2006)
J Pathol
, vol.210
, Issue.2
, pp. 137-140
-
-
Minoo, P.1
Jass, J.R.2
-
34
-
-
16544363110
-
Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation
-
Nagasaka T, Sasamoto H, Notohara K, et al. Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation. J Clin Oncol. 2004; 22: 4584-94.
-
(2004)
J Clin Oncol
, vol.22
, pp. 4584-4594
-
-
Nagasaka, T.1
Sasamoto, H.2
Notohara, K.3
-
35
-
-
9144271690
-
Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation
-
Domingo E, Espin E, Armengol M, et al. Activated BRAF targets proximal colon tumors with mismatch repair deficiency and MLH1 inactivation. Genes Chromosomes Cancer 2004; 39: 138-42.
-
(2004)
Genes Chromosomes Cancer
, vol.39
, pp. 138-142
-
-
Domingo, E.1
Espin, E.2
Armengol, M.3
-
36
-
-
0347382321
-
Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas
-
Koinuma K, Shitoh K, Miyakura Y, et al. Mutations of BRAF are associated with extensive hMLH1 promoter methylation in sporadic colorectal carcinomas. Int J Cancer 2004; 108: 237-42.
-
(2004)
Int J Cancer
, vol.108
, pp. 237-242
-
-
Koinuma, K.1
Shitoh, K.2
Miyakura, Y.3
-
37
-
-
22244472992
-
Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers
-
Samowitz WS, Sweeney C, Herrick J, et al. Poor survival associated with the BRAF V600E mutation in microsatellite-stable colon cancers. Cancer Res 2005, 65: 6063-9.
-
(2005)
Cancer Res
, vol.65
, pp. 6063-6069
-
-
Samowitz, W.S.1
Sweeney, C.2
Herrick, J.3
-
38
-
-
16544381802
-
Promoter hy-permethylation frequency and BRAF mutations distinguish hereditary nonpolyposis colon cancer from sporadic MSI-H colon cancer
-
McGivern A, Wynter CV, Whitehall VL, et al. Promoter hy-permethylation frequency and BRAF mutations distinguish hereditary nonpolyposis colon cancer from sporadic MSI-H colon cancer. Fam Cancer 2004, 3: 101-7.
-
(2004)
Fam Cancer
, vol.3
, pp. 101-107
-
-
McGivern, A.1
Wynter, C.V.2
Whitehall, V.L.3
-
39
-
-
2942514668
-
Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer
-
Miyaki M, Iijima T, Yamaguchi T, Kadofuku T, Funata N, Mori T. Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer. Cancer Lett 2004, 211: 105-9.
-
(2004)
Cancer Lett
, vol.211
, pp. 105-109
-
-
Miyaki, M.1
Iijima, T.2
Yamaguchi, T.3
Kadofuku, T.4
Funata, N.5
Mori, T.6
-
40
-
-
4444311092
-
BRAF screening as a low cost effective strategy for simplifying HNPCC genetic testing
-
Domingo E, Laiho P, Ollikainen M, et al. BRAF screening as a low cost effective strategy for simplifying HNPCC genetic testing. J Med Genet 2004, 41: 664-8.
-
(2004)
J Med Genet
, vol.41
, pp. 664-668
-
-
Domingo, E.1
Laiho, P.2
Ollikainen, M.3
-
41
-
-
20544437157
-
BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes
-
Domingo E, Niessen RC, Oliveira C, et al. BRAF-V600E is not involved in the colorectal tumorigenesis of HNPCC in patients with functional MLH1 and MSH2 genes. Oncogene 2005; 24: 3995-8.
-
(2005)
Oncogene
, vol.24
, pp. 3995-3998
-
-
Domingo, E.1
Niessen, R.C.2
Oliveira, C.3
-
42
-
-
33845672260
-
Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer
-
Samowitz WS, Albertsen H, Sweeney C, et al. Association of smoking, CpG island methylator phenotype, and V600E BRAF mutations in colon cancer. J Natl Cancer Inst 2006; 98: 1731-8.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1731-1738
-
-
Samowitz, W.S.1
Albertsen, H.2
Sweeney, C.3
-
43
-
-
33845691410
-
Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer
-
Slattery ML, Curtin K, Sweeney C, et al. Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int J Cancer 2007; 120: 656-63.
-
(2007)
Int J Cancer
, vol.120
, pp. 656-663
-
-
Slattery, M.L.1
Curtin, K.2
Sweeney, C.3
-
44
-
-
6444228426
-
Mismatch repair protein MSH2 expression and prognosis of colorectal cancer patients
-
Bernardo CG, Gonzalez JJ, Sanz L, et al. Mismatch repair protein MSH2 expression and prognosis of colorectal cancer patients. Int J Biol Markers 2004; 19: 190-5.
-
(2004)
Int J Biol Markers
, vol.19
, pp. 190-195
-
-
Bernardo, C.G.1
Gonzalez, J.J.2
Sanz, L.3
|