QSAR studies of 4,5-dihydro-4-oxo-3H-imidazo[4,5-c]pyridines as potent angiotensin II receptor antagonists by MLR and NLR analysis

Arkivoc

Volumn 2007, Issue 1, 2007, Pages 189-204

  Narasimhan, Balasubramanian ^a   Dhake, Avinash ^b   Mourya, Vishnukant ^c  

^a GURU JAMBHESHWAR UNIVERSITY OF SCIENCE AND TECHNOLOGY   (India)

^b LBRao Institute of Pharmaceutical Education and Research   (India)

^c GOVERNMENT COLLEGE OF PHARMACY   (India)

Author keywords

Ang II receptor antagonist; Leave one out method; MLR; Molecular descriptor; NLR

Indexed keywords

EID: 34248359982     PISSN: 1551-7012     EISSN: 14246376     Source Type: Journal    
DOI: 10.3998/ark.5550190.0008.121     Document Type: Article

References (46)

1. Sealey, J. E.; Laragh, J. H. The Rennin-Angiotensin-Aldosterone System for Normal Regulation of Blood Pressure and Sodium and Potassium Homeostasis. In Hypertension: Pathophysiology, Diagnosis And Management, Berner, J. H.; Laragh, B. M., Eds., Raven Press: New York, 1990; pp 1287.
2. Blankey, C. J.; Hodges, J. C.; Klutchko, S. R.; Himmelsbach, R. J.; Chucholowski, A.; Connolly, C. J.; Neergaard, S. J.; Niewwenhze, M. S.; Sebastian, A.; Quin, J.; Essenberg,, A. D.; Cohen, D. M. J. Med. Chem. 1991, 34, 3248.
3. Dudley, D. T.; Panek, R. L.; Major, T.; Lu, G. H.; Bruns, R. F.; Klinkefus, B. A.; Hodges, J. C.; Weishaar, R. E. Mol. Pharmacol. 1990, 80, 370.
4. Whitebread, S.; Mele, M.; Kamber, B.; de Gasparo, M. Biochem. Biophys. Res. Commun. 1989, 163, 284.
5. Chiu, A. T.; Herblin, W. F.; McCall, D. E.; Ardecky, R. J.; Carini, D. J.; Duncia, J. V.; Pease, L. J.; Wong, P. C.; Wexier, R. R.; Johnson, A. L.; Timmermanns, P. B. M. W. M. Biochem. Biophys. Res. Commun. 1989, 165, 196.
6. Timmermanns, P. B. M. W. M.; Wong, P. C.; Chiu, A. T.; Herblin, W. F.; Benfield, P.; Carini, D. J.; Lee, R. J.; Wexler, R. R.; Saye, J. A. M.; Smith, R. D. Pharmacol. Rev. 1993, 45, 205.
7. Catt, K. J.; Sandberg, K.; Balla, T. Angiotensin II Receptors and Signal Transduction Mechanisms. In Cellular And Molecular Biology of the Renin Angiotensin System, Eds., Raizada, M. K.; Philips, M. I.; Sumners, C. CRC Press Inc.: Boca Raton, FL, 1993; pp 307.
8. Mukoyama, M.; Nakaijima, M.; Horiuchi, M.; Sasamura, H.; Pratt, R. E.; Dzau, V. J. J. Biol. Chem. 1993, 268, 24539.
9. Kambayashi, Y.; Bardhan, S.; Takahashi, K.; Tsuzuki, S.; Inui, H.; Hamakubo, T.; Inagami, T. J. Biol. Chem. 1993, 26, 24543.
10. Bottari, S. P.; King, I. N.; Reichlin, S.; Dahlstroem, I.; Lyndon, N.; de Gasparo, M. Biochem. Biophys. Res. Commun. 1993, 183, 206.
11. Bottari, S. P.; de Gasparo, M.; Stockelings, U. M.; Levens, N. R. Front. Neuroendocrinol. 1993, 14, 132.
12. Keiser, J. A.; Olszewski, B.; Hicks, G.; Ryan, M. J.; Hodges, J. FASEB J. 1993, 7, A654.
13. Kubo, K.; Kohara, Y.; Imamiya, E.; Sigiura, Y.; Inada, Y.; Furukawa, Y.; Nishikawa, K.; Naka, T. J. Med. Chem. 1993, 36, 2182.
14. Nicolai, E.; Cure, G.; Goyard, J.; Kirchner, M.; Teulon, J. M.; Versigny, A.; Cazes, M.; Virone-Oddos, A.; Caussade, F.; Cloarec, A. Eur. J. Med. Chem. 1995, 30, 365.
15. Whitesitt, C. A.; Steinberg, M. I.; Zimmerman, K. M.; Wiest, S. A.; Lifer, S. L.; Reel, J. K.; Simon, R. L. FASEB J. 1992, 5, 5412.
16. Allen, E. E.; de Laszlo, S. E.; Huang, S. X.; Quagliato, C. S.; Greenlee, W. J.; Chang, R. S.; Chen, T. B.; Faust, K. A.; Lotti, V. J. Bioorg. Med. Chem. Lett. 1993, 3, 1293.
17. Gupta, S. P.; Mathur, A. N.; Nagappa, A. N.; Kumar, D.; Kumaran, S. Eur. J. Med. Chem. 2003, 38, 867.
18. Narasimhan, B.; Kothawade, U. R.; Pharande, D. S.; Mourya, V. K.; Dhake, A. S. Indian J. Chem., 2003, 42B, 2828.
19. Narasimhan, B.; Belsare, D.; Pharande, P.; Mourya, V.; Dhake, A. Eur. J. Med. Chem., 2004, 39, 827.
20. Narasimhan, B.; Mourya, V.; Dhake, A. Biorg. Med. Chem. Lett. 2006, 16, 3023.
21. Narasimhan, B.; Mourya, V. K.; Dhake, A. S. Khim.-Farm. Zh., 2007, 3, 120.
22. Narasimhan, B.; Kumari, M.; Jain, N.; Dhake, A.; Sundaravelan, C. Biorg. Med. Chem. Lett. 2006, 16, 4951.
23. Gangwal, N. A.; Narasimhan, B.; Mourya, V. K.; Dhake, A. S. Indian J. Het. Chem., 2003, 12, 201.
24. Narasimhan, B.; Kumari, M.; Dhake, A.; Sundaravelan, C. ARKIVOC, 2006, xiii, 73.
25. Narasimhan, B.; Ansari, M. A.; Singh, N.; Mourya, V.K .; Dhake, A. S. Chem. Pharm. Bull. 2006, 54, 1067.
26. Mederski, W. W. K. R.; Dorsch, D.; Osswald, M.; Schwatz, H.; Beier, N.; Christadler, M.; Minck, K. O.; Schelling, P.; Schmitges, C. J. Eur. J. Med. Chem. 1997, 32, 479.
27. Furusjo, E.; Svenson, A.; Rahmberg, M.; Andersson, M. Chemosphere 2006, 63, 99.
28. TSAR 3D, Version 3.3, Oxford Molecular Limited, 2000.
29. Kubinyi, H. In QSAR-Hansch Analysis and Related Approaches; Vol-1; VCH Publishers: New York; 1993: pp 1.
30. Hansch, C. In Comprehensive Medicinal Chemistry; Vol. 4; 1st Ed.; Pergamon Press: Oxford, 1990; pp 9.
31. Wiener, H. J. Am. Chem. Soc. 1947, 69, 17.
32. Randic, M. J. Am. Chem. Soc. 1975, 97, 6609.
33. Kier, L. B.; Hall, L. H. In Molecular Connectivity in Structure-Activity Analysis; Research Studies Press: Letchworth, 1986; pp 20.
34. Zefirov, N. S.: Kirpichenok, M. A.; Izmallov, F. F.; Trofirnov, M. I. Dokl. Akad. Nauk SSSR 1987, 296, 883.
35. Kirpichenok, M. A.; Zefirov, N. S. Zh. Org. Khim. 1987, 23, 673.
36. Stanton, D. T.; Jurs, P. C. Anal. Chem. 1990, 62, 2323.
37. Stanton, D. T.; Egolf, L. M.; Jurs, P. C.; Hicks, M. G. J. Chem. Inf Comput. Sci. 1992, 32, 306.
38. Rohrbaugh, R. H.; Jurs, P. C. Anal. Chim. Acta 1987, 199, 99.
39. Karelson, M. In Molecular Descriptors in QSAR/QSPR; John Wiley & Sons: New York, 2000; pp 100.
40. Karelson, M.; Lobanov, V. S.; Katritzky, A. R. Chem. Rev. 1996, 96, 1027.
41. Breneman, C. M.; Martinov, M. In Molecular Electrostatic Potentials: Concepts and Applications, Theoretical and Computational Chemistry; Vol. 3; Eds. Murray, J. S.; Sen, K., Eds., Elsevier Science: Amsterdam, 1996; pp 54.
42. Monasterios, M.; Escorche, M.; Avendano, M. J. Mol. Struct. 2005, 748, 49.
43. Monasterios, M.; Avendano, M.; Amaro, M. I.; Infante, W.; Charris, J. J. Mol. Struct. 2006, 798, 102.
44. Agarwal, V. K.; Singh, J.; Mishra, K. C.; Khadikar, P. V.; Jaliwala, Y. A. Arkivoc 2006, (ii), 162.
45. Mandloi, D.; Joshi, S.; Khadikar, P. V.; Khosla, N. Bioorg. Med. Chem. Lett. 2005, 15, 405.
46. Pinheiro, A. A. C.; Borges, R. S.; Santos, L. S.; Alves, C. N. J. Mol. Struct. (Theochem). 2004, 672, 215.