Permeability of atenolol and propranolol in the presence of dimethyl sulfoxide in rat single-pass intestinal perfusion assay with liquid chromatography/UV detection

Biomedical Chromatography

Volumn 21, Issue 5, 2007, Pages 484-490

  Venkatesh, Gantala ^a   Ramanathan, S ^a   Nair, N K ^a   Mansor, S M ^a   Sattar, Munavvar Abdul ^b   Khan, Md Abdul Hye ^b   Navaratnam, V ^a  

^a SCHOOL OF PHYSICS   (Malaysia)

^b SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

Author keywords

Atenolol; Dimethyl sulfoxide; In situ intestinal permeability; Propranolol; RP HPLC

Indexed keywords

DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; RATS;

ATENOLOL; IN SITU INTESTINAL PERMEABILITY; INTESTINAL PERMEABILITIES; PROPRANOLOL; RP-HPLC; RP-HPLC/UV; SIMPLE++; SIMULTANEOUS DETERMINATIONS; SINGLE PASS; UV DETECTION;

DIMETHYL SULFOXIDE;

ACETONITRILE; AMMONIUM ACETATE; ATENOLOL; DIMETHYL SULFOXIDE; PENTOBARBITAL; PROPRANOLOL;

ACCURACY; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG PENETRATION; FLOW RATE; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; MALE; NONHUMAN; PH; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SENSITIVITY ANALYSIS; SPRAGUE DAWLEY RAT; ULTRAVIOLET RADIATION; VALIDATION PROCESS;

RATTUS;

EID: 34248357210     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.781     Document Type: Article

References (19)

1. Amidon GL, Sinko PJ and Fleisher D. Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier mediated compounds. Pharmaceutical Research 1988; 5: 651-654.
2. Amidon GL, Lennernas H, Shah VP and Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharmceutical Research 1995; 12: 413-420.
3. Balimane PV, Yong-Hae H and Chong S. Current industrial practices of assessing permeability and p-glycoprotein interactions. The AAPS Journal 2006; 8: 1-13.
4. Bermejo M, Avdeef A, Ruiz A, Nalda R, Ruell JA, Tsinman O, González I, Fernández C, Sánchez G, Garrigues TM and Merino V. PAMPA- a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones. European Journal of Pharmaceutical Sciences 2004; 21: 429-441.
5. Chawla S, Ghosh S, Sihorkar V, Nellore R, Kumar TRS and Srinivas NR. High-performance liquid chromatography method development and validation for simultaneous determination of five model compounds, antipyrine, metoprolol, ketoprofen, furosemide and phenol red, as a tool for the standardization of rat in situ intestinal permeability studies using timed wavelength detection. Biomedical Chromatography 2006; 20: 349-357.
6. Hidalgo IJ. Assessing the absorption of new pharmaceuticals. Current Topics in Medicinal Chemistry 2001; 1: 385-401.
7. Issa C, Guptha P and Bansal AK. Implications of density correction in gravimetric method for water flux determination using rat single-pass intestinal perfusion technique: a technical note. AAPS Pharm Sci Tech 2003; 4: 1-6.
8. Kumar TRS, Chawla S, Nachaegari SK, Singh SK and Srinivas NR. Validated HPLC analytical method with programmed wavelength UV detection for simultaneous determination of DRF-4367 and Phenol red in rat in situ intestinal perfusion study. Journal of Pharmaceutical and Biomedical Analysis 2005; 38: 173-179.
9. Lipinski CA, Lombardo F, Dominy BW and Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced Drug Delivery Reviews 2001; 46: 3-26.
10. Munoz MJ, Merino-Sanjuan M, Garcia RL, Casabo VG, Manez-Castillejo FJ and Nacher A. Use of nonlinear mixed effect modeling for the intestinal absorption data: Application to ritonavir in the rat. European Journal of Pharmaceutics and Biopharmaceutics 2005; 61: 20-26.
11. Oda M, Saitoh H, Kobayashi M and Aungst BJ. β-Cyclodextrin as a suitable solubilizing agent for in situ absorption study of poorly water-soluble drugs. International Journal of Pharmaceutics. 2004; 280: 95-102.
12. Salphati L, Childers K, Pan L, Tsutsui K and Takahashi L. Evaluation of a single pass intestinal-perfusion method in rat for the prediction of absorption in man. Journal of Pharmacy and Pharmacology 2001; 53: 1007-1013.
13. Sorbye H, Guttu K, Gislason H, Grong K and Svanes K. Gastric mucosal injury and associated changes in mucosal blood flow and gastric fluids secretion caused by dimethyl sulfoxide (DMSO) in rats. Digestive Diseases and Sciences 1993; 38: 1243-1250.
14. USFDA. Guidance for Industry, Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System. US Administration, Centre for Drug Evaluation and Research: Rockville, MD, 2000.
15. Varma MVS, Kapoor N, Sarkar M and Panchagnula R. Simultaneous determination of digoxin and permeability markers in rat in situ intestinal perfusion samples by RP-HPLC. Journal of Chromatography B 2004; 813: 347-352.
16. Varma MVS and Panchagnula R. Prediction of In Vivo Intestinal absorption enhancement on P-glycoprotein inhibition, from rat in situ permeability. Journal of Pharmaceutical Sciences 2005; 94 :1694-1704.
17. Varma MVS, Sarkar M, Kapoor N and Panchagnula R. pH-dependent functional activity of P-glycoprotein in limiting intestinal absorption of protic drugs 1.Simultaneous determination of quinidine and permeability markers in rat in situ perfusion samples. Journal of Chromatography B 2005; 816: 243-249.
18. Yamashita S, Furubayashi T, Kataoka M, Sakane T, Sezaki H and Tokuda H. Optimized conditions for prediction of intestinal drug permeability using Caco-2 cells. European Journal of Pharmaceutical Sciences 2000; 10: 195-204.
19. Zhu C, Jiang L, Chen TM and Hwang KK. A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential. European Journal of Medicinal Chemistry 2002; 37: 399-407.