Crystal Structure and Allosteric Regulation of the Cytoplasmic Escherichia coli l-Asparaginase I

Journal of Molecular Biology

Volumn 369, Issue 3, 2007, Pages 794-811

  Yun, Mi Kyung ^a   Nourse, Amanda ^a   White, Stephen W ^a,b   Rock, Charles O ^a,b   Heath, Richard J ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

allostery; enzyme mechanisms; kinetics; leukemia; positive cooperativity

Indexed keywords

ASPARAGINASE; CARBOXYL GROUP; CYTOPLASM PROTEIN; DIMER; MONOMER; TETRAMER;

ALLOSTERISM; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HYDROGEN BOND; KINETICS; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN QUATERNARY STRUCTURE; ULTRACENTRIFUGATION; X RAY CRYSTALLOGRAPHY;

ESCHERICHIA COLI;

EID: 34248232994     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2007.03.061     Document Type: Article

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