Eosinophilic esophagitis in adults and children: Evidence for a food allergy component in many patients

Current Opinion in Allergy and Clinical Immunology

Volumn 7, Issue 3, 2007, Pages 274-278

  Spergel, Jonathan M ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Atopy patch test; Elemental diet; Eosinophilic esophagitis; Food allergies; Prick skin test

Indexed keywords

FLUTICASONE PROPIONATE; PLACEBO; PROTON PUMP INHIBITOR;

ATOPY; CALORIC INTAKE; DIET RESTRICTION; DIET THERAPY; ELEMENTAL DIET; EOSINOPHIL COUNT; EOSINOPHILIC ESOPHAGITIS; ESOPHAGOGASTRODUODENOSCOPY; ESOPHAGUS BIOPSY; FOOD ALLERGY; FOOD COMPOSITION; GASTROESOPHAGEAL REFLUX; HUMAN; NUTRITION; PATCH TEST; PATHOGENESIS; PRICK TEST; PRIORITY JOURNAL; REVIEW; SKIN TEST;

ADULT; CHILD; EOSINOPHILIA; ESOPHAGITIS; FOOD HYPERSENSITIVITY; GASTROESOPHAGEAL REFLUX; HUMANS; SKIN TESTS;

EID: 34248184532     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0b013e32813aee4a     Document Type: Review

References (37)

1. Liacouras CA, Spergel JM, Ruchelli E, et al. Eosinophilic esophagitis: a 10-year experience in 381 children. Clin Gastroenterol Hepatol 2005; 3:1198-1206.
2. Blanchard C, Wang N, Rothenberg ME. Eosinophilic esophagitis: pathogenesis, genetics, and therapy. J Allergy Clin Immunol 2006; 118:1054-1059. An excellent recent review of eosinophilic esophagitis including pathogenesis.
3. Landres RT, Kuster GG, Strum WB. Eosinophilic esophagitis in a patient with vigorous achalasia. Gastroenterology 1978; 74:1298-1301.
4. Kelly K, Lazenby A, Rowe P, et al. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology 1995; 109:1503-1512.
5. Guajardo J, Plotnick L, Fende J, et al. Eosinophil-associated gastrointestinal disorders: a world-wide-web based registry. J Pediatr 2002; 141:576-581.
6. Noel RJ, Putnam PE, Rothenberg ME. Eosinophilic esophagitis. N Engl J Med 2004; 351:940-941.
7. Cherian S, Smith NM, Forbes DA. Rapidly increasing prevalence of eosinophilic oesophagitis in Western Australia. Arch Dis Child 2006; 91:1000-1004.
8. Ronkainen J, Talley NJ, Aro P, et al. Prevalence of oesophageal eosinophils and eosinophilic oesophagitis in adults: the population-based Kalixanda study. Gut 29 November 2006; [E-pub ahead of print].
9. Nelson SP, Chen EH, Syniar GM, Christoffel KK. Prevalence of symptoms of gastroesophageal reflux during childhood: a pediatric practice-based survey. Pediatric Practice Research Group. Arch Pediatr Adolesc Med 2000; 154:150-154.
10. Spergel JM, Andrews T, Brown-Whitehorn TF, et al. Treatment of eosinophilic esophagitis with specific food elimination diet directed by a combination of skin prick and patch tests. Ann Allergy Asthma Immunol 2005; 95:336-343.
11. Simon D, Marti H, Heer P, et al. Eosinophilic esophagitis is frequently associated with IgE-mediated allergic airway diseases. J Allergy Clin Immunol 2005; 115:1090-1092.
12. Yan BM, Shaffer EA. Eosinophilic esophagitis: a newly established cause of dysphagia. World J Gastroenterol 2006; 12:2328-2334.
13. Gonsalves N, Policarpio-Nicolas M, Zhang Q, et al. Histopathologic variability and endoscopic correlates in adults with eosinophilic esophagitis. Gastrointest Endosc 2006; 64:313-319.
14. Furuta GT, Straumann A. Review article: the pathogenesis and management of eosinophilic oesophagitis. Aliment Pharmacol Ther 2006; 24:173-182.
15. Liacouras CA, Wenner WJ, Brown K, Ruchelli E. Primary eosinophilic esophagitis in children: successful treatment with oral corticosteroids. J Pediatr Gastroenterol Nutr 1998; 26:380-385.
16. Orenstein SR, Shalaby TM, Di Lorenzo C, et al. The spectrum of pediatric eosinophilic esophagitis beyond infancy: a clinical series of 30 children. Am J Gastroenterol 2000; 95:1422-1430.
17. Steiner SJ, Kernek KM, Fitzgerald JF. Severity of basal cell hyperplasia differs in reflux versus eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2006; 42:506-509.
18. Ngo P, Furuta GT, Antonioli DA, Fox VL. Eosinophils in the esophagus - peptic or allergic eosinophilic esophagitis? Case series of three patients with esophageal eosinophilia. Am J Gastroenterol 2006; 101:1666-1670.
19. Fogg MI, Ruchelli E, Spergel JM. Pollen and eosinophilic esophagitis. J Allergy Clin Immunol 2003; 112:796-797.
20. Onbasi K, Sin AZ, Doganavsargil B, et al. Eosinophil infiltration of the oesophageal mucosa in patients with pollen allergy during the season. Clin Exp Allergy 2005; 35:1423-1431.
21. Gupta SK, Fitzgerald JF, Kondratyuk T, HogenEsch H. Cytokine expression in normal and inflamed esophageal mucosa: a study into the pathogenesis of allergic eosinophilic esophagitis. J Pediatr Gastroenterol Nutr 2006; 42:22-26.
22. Blanchard C, Wang N, Stringer KF, et al. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J Clin Invest 2006; 116:536-547. An important paper examining the potential mechanism and genetic profile in eosinophilic esophagitis.
23. Dobbins JW, Sheahan DG, Behar J. Eosinophilic gastroenteritis with esophageal involvement. Gastroenterology 1977; 72:1312-1316.
24. Kelly KJ, Lazenby AJ, Rowe PC, et al. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology 1995; 109:1503-1512.
25. Markowitz JE, Spergel JM, Ruchelli E, Liacouras CA. Elemental diet is an effective treatment for eosinophilic esophagitis in children and adolescents. Am J Gastroenterol 2003; 98:777-782.
26. Spergel JM, Beausoleil JL, Mascarenhas M, Liacouras CA. The use of skin prick tests and patch tests to identify causative foods in eosinophilic esophagitis. J Allergy Clin Immunol 2002; 109:363-368.
27. Spergel JM, Brown-Whitehorn T. The use of patch testing in the diagnosis of food allergy. Curr Allergy Asthma Rep 2005; 5:86-90.
28. Kagalwalla AF, Sentongo TA, Ritz S, et al. Effect of six-food elimination diet on clinical and histologic outcomes in eosinophilic esophagitis. Clin Gastroenterol Hepatol 2006; 4:1097-1102. This outstanding paper examines the success of a six-food elimination diet in eosinophilic esophagitis, and confirms that food allergies are causative.
29. De Angelis P, Markowitz JE, Torroni F, et al. Paediatric eosinophilic oesophagitis: towards early diagnosis and best treatment. Dig Liver Dis 2006; 38:245-251.
30. Martin-Munoz MF, Lucendo AJ, Navarro M, et al. Food allergies and eosinophilic esophagitis - two case studies. Digestion 2006; 74:49-54.
31. Sgouros SN, Bergele C, Mantides A. Eosinophilic esophagitis in adults: a systematic review. Eur J Gastroenterol Hepatol 2006; 18:211-217. A through review of adult eosinophilic esophagitis.
32. Simon D, Straumann A, Wenk A, et al. Eosinophilic esophagitis in adults - no clinical relevance of wheat and rye sensitizations. Allergy 2006; 61:1480-1483.
33. Yamazaki K, Murray JA, Arora AS, et al. Allergen-specific in vitro cytokine production in adult patients with eosinophilic esophagitis. Dig Dis Sci 2006; 51:1934-1941.
34. Anton Remirez J, Escudero R, Caceres O, Fernandez-Benitez M. Eosinophilic esophagitis. Allergol Immunopathol (Madr) 2006; 34:79-81.
35. Noel RJ, Putnam PE, Collins MH, et al. Clinical and immunopathologic effects of swallowed fluticasone for eosinophilic esophagitis. Clin Gastroenterol Hepatol 2004; 2:568-575.
36. Remedios M, Campbell C, Jones DM, Kerlin P. Eosinophilic esophagitis in adults: clinical, endoscopic, histologic findings, and response to treatment with fluticasone propionate. Gastrointest Endosc 2006; 63:3-12.
37. Konikoff MR, Noel RJ, Blanchard C, et al. A randomized, double-blind, placebo controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology 2006; 131:1381-1391. The first randomized placebo controlled trial in the treatment of eosinophilic esophagitis. Fifty per cent of the patients improved with medical therapy.