New 5-substituted thiazolo[3,2-b][1,2,4]triazol-6-ones: Synthesis and anticancer evaluation

European Journal of Medicinal Chemistry

Volumn 42, Issue 5, 2007, Pages 641-648

  Lesyk, Roman ^a   Vladzimirska, Olena ^a   Holota, Serhiy ^a   Zaprutko, Lucjusz ^b   Gzella, Andrzej ^b  

^a DANYLO HALYTSKY LVIV NATIONAL MEDICAL UNIVERSITY   (Ukraine)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Anticancer activity; Thiazolo 3,2 b 1,2,4 triazol 6 ones; X ray study

Indexed keywords

4 THIAZOLIDINONE DERIVATIVE; 5 YLIDENE [1,3]THIAZOLO[3,2 B][1,2,4]TRIAZOL 6 ONE DERIVATIVE; ANTINEOPLASTIC AGENT; BH3 PROTEIN; N (PHENYL) (6 OXO 5,6 DIHYDRO[1,3]THIAZOL[3,2 B][1,2,4]TRIAZOL 5 YL]ACETAMIDE DERIVATIVE; PROTEIN BCL XL; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; KIDNEY CANCER; LEUKEMIA; MELANOMA; MICROTUBULE ASSEMBLY; NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION; X RAY; X RAY ANALYSIS;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; TRIAZOLES;

EID: 34248173947     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2006.12.006     Document Type: Article

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