-
1
-
-
0842296490
-
Clinical phenotype of families with longevity
-
Atzmon G, Schechter C, Greiner W, Davidson D, Rennert G, Barzilai N. 2004. Clinical phenotype of families with longevity. J Am Geriatr Soc 52:274-277.
-
(2004)
J Am Geriatr Soc
, vol.52
, pp. 274-277
-
-
Atzmon, G.1
Schechter, C.2
Greiner, W.3
Davidson, D.4
Rennert, G.5
Barzilai, N.6
-
2
-
-
13444252277
-
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
-
Bertoncini CW, Jung YS, Fernandez CO, Hoyer W, Griesinger C, Jovin TM, Zweckstetter M. 2005. Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein. Proc Natl Acad Sci U S A 102:1430-1435.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1430-1435
-
-
Bertoncini, C.W.1
Jung, Y.S.2
Fernandez, C.O.3
Hoyer, W.4
Griesinger, C.5
Jovin, T.M.6
Zweckstetter, M.7
-
3
-
-
9444233904
-
Differential expression of α-synuclein isoforms in dementia with Lewy bodies
-
Beyer K, Lao JI, Carrato C, Mate JL, Lopez D, Ferrer I, Ariza A. 2004. Differential expression of α-synuclein isoforms in dementia with Lewy bodies. Neuropathol Appl Neurobiol 30:601-607.
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 601-607
-
-
Beyer, K.1
Lao, J.I.2
Carrato, C.3
Mate, J.L.4
Lopez, D.5
Ferrer, I.6
Ariza, A.7
-
4
-
-
33747778534
-
Low α-synuclein 126 mRNA levels in dementia with Lewy bodies and Alzheimer disease
-
Beyer K, Humbert J, Ferrer A, Lao JI, Carrato C, López D, Ferrer I, Ariza A. 2006. Low α-synuclein 126 mRNA levels in dementia with Lewy bodies and Alzheimer disease. Neuroreport 17:1327-1330.
-
(2006)
Neuroreport
, vol.17
, pp. 1327-1330
-
-
Beyer, K.1
Humbert, J.2
Ferrer, A.3
Lao, J.I.4
Carrato, C.5
López, D.6
Ferrer, I.7
Ariza, A.8
-
5
-
-
0038206578
-
Gene microarrays in hippocampal aging: Statistical profiling identifies novel processes correlated with cognitive impairment
-
Blalock EM, Chen KC, Sharrow K, Herman JP, Porter NM, Foster TC, Landfield PW. 2003. Gene microarrays in hippocampal aging: statistical profiling identifies novel processes correlated with cognitive impairment. J Neurosci 23:3807-3819.
-
(2003)
J Neurosci
, vol.23
, pp. 3807-3819
-
-
Blalock, E.M.1
Chen, K.C.2
Sharrow, K.3
Herman, J.P.4
Porter, N.M.5
Foster, T.C.6
Landfield, P.W.7
-
6
-
-
1942534598
-
Effects of Parkinson's disease-linked mutations on the structure of lipid-associated α-synuclein
-
Bussell R Jr, Eliezer D. 2004. Effects of Parkinson's disease-linked mutations on the structure of lipid-associated α-synuclein. Biochemistry 43:4810-4818.
-
(2004)
Biochemistry
, vol.43
, pp. 4810-4818
-
-
Bussell Jr, R.1
Eliezer, D.2
-
7
-
-
0037109727
-
Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking α-synuclein
-
Cabin DE, Shimazu K, Murphy D, Cole NB, Gottschalk W, McIlwain KL, Orrison B, Chen A, Ellis CE, Paylor R, Lu B, Nussbaum RL. 2002. Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking α-synuclein. J Neurosci 22:8797-8807.
-
(2002)
J Neurosci
, vol.22
, pp. 8797-8807
-
-
Cabin, D.E.1
Shimazu, K.2
Murphy, D.3
Cole, N.B.4
Gottschalk, W.5
McIlwain, K.L.6
Orrison, B.7
Chen, A.8
Ellis, C.E.9
Paylor, R.10
Lu, B.11
Nussbaum, R.L.12
-
8
-
-
0028965513
-
The NACP/ synuclein gene: Chromosomal assignment and screening for alterations in Alzheimer disease
-
Campion D, Martin C, Heilig R, Charbonnier F, Moreau V, Flaman JM, Petit JL, Hannequin D, Brice A, Frebourg T. 1995. The NACP/ synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease. Genomics 26:254-257.
-
(1995)
Genomics
, vol.26
, pp. 254-257
-
-
Campion, D.1
Martin, C.2
Heilig, R.3
Charbonnier, F.4
Moreau, V.5
Flaman, J.M.6
Petit, J.L.7
Hannequin, D.8
Brice, A.9
Frebourg, T.10
-
9
-
-
18844400549
-
Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians
-
Cellini E, Nacmias B, Olivieri F, Ortenzi L, Tedde A, Bagnoli S, Petruzzi C, Franceschi C, Sorbi S. 2005. Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians. Mech Ageing Dev 126:826-828.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 826-828
-
-
Cellini, E.1
Nacmias, B.2
Olivieri, F.3
Ortenzi, L.4
Tedde, A.5
Bagnoli, S.6
Petruzzi, C.7
Franceschi, C.8
Sorbi, S.9
-
10
-
-
0038341134
-
A broken α-helix in folded α-synuclein
-
Chandra S, Chen X, Rizo J, Jahn R, Sudhof TC. 2003. A broken α-helix in folded α-synuclein. J Biol Chem 278:15313-15318.
-
(2003)
J Biol Chem
, vol.278
, pp. 15313-15318
-
-
Chandra, S.1
Chen, X.2
Rizo, J.3
Jahn, R.4
Sudhof, T.C.5
-
11
-
-
0025906695
-
Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium
-
Chu CS, Trapnell BC, Murtagh JJ Jr, Moss J, Dalemans W, Jallat S, Mercenier A, Pavirani A, Lecocq JP, Cutting GR, et al. 1991. Variable deletion of exon 9 coding sequences in cystic fibrosis transmembrane conductance regulator gene mRNA transcripts in normal bronchial epithelium. EMBO J 10:1355-1363.
-
(1991)
EMBO J
, vol.10
, pp. 1355-1363
-
-
Chu, C.S.1
Trapnell, B.C.2
Murtagh Jr, J.J.3
Moss, J.4
Dalemans, W.5
Jallat, S.6
Mercenier, A.7
Pavirani, A.8
Lecocq, J.P.9
Cutting, G.R.10
-
12
-
-
0027502580
-
Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA
-
Chu CS, Trapnell BC, Curristin S, Cutting GR, Crystal RG. 1993. Genetic basis of variable exon 9 skipping in cystic fibrosis transmembrane conductance regulator mRNA. Nat Genet 3:151-156.
-
(1993)
Nat Genet
, vol.3
, pp. 151-156
-
-
Chu, C.S.1
Trapnell, B.C.2
Curristin, S.3
Cutting, G.R.4
Crystal, R.G.5
-
13
-
-
0032518518
-
Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation
-
Cuppens H, Lin W, Jaspers M, Costes B, Teng H, Vankeerberghen A, Jorissen M, Droogmans G, Reynaert I, Goossens M, Nilius B, Cassiman JJ. 1998. Polyvariant mutant cystic fibrosis transmembrane conductance regulator genes. The polymorphic (Tg)m locus explains the partial penetrance of the T5 polymorphism as a disease mutation. J Clin Invest 101:487-496.
-
(1998)
J Clin Invest
, vol.101
, pp. 487-496
-
-
Cuppens, H.1
Lin, W.2
Jaspers, M.3
Costes, B.4
Teng, H.5
Vankeerberghen, A.6
Jorissen, M.7
Droogmans, G.8
Reynaert, I.9
Goossens, M.10
Nilius, B.11
Cassiman, J.J.12
-
14
-
-
2342457804
-
Abnormal α-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease
-
Dalfo E, Barrachina M, Rosa JL, Ambrosio S, Ferrer I. 2004. Abnormal α-synuclein interactions with rab3a and rabphilin in diffuse Lewy body disease. Neurobiol Dis 16:92-97.
-
(2004)
Neurobiol Dis
, vol.16
, pp. 92-97
-
-
Dalfo, E.1
Barrachina, M.2
Rosa, J.L.3
Ambrosio, S.4
Ferrer, I.5
-
15
-
-
0032540327
-
Stabilization of α-synuclein secondary structure upon binding to synthetic membranes
-
Davidson WS, Jonas A, Clayton DF, George JM. 1998. Stabilization of α-synuclein secondary structure upon binding to synthetic membranes. J Biol Chem 273:9443-9449.
-
(1998)
J Biol Chem
, vol.273
, pp. 9443-9449
-
-
Davidson, W.S.1
Jonas, A.2
Clayton, D.F.3
George, J.M.4
-
16
-
-
33644558377
-
Expression profiling in the aging brain: A perspective
-
Galvin JE, Ginsberg SD. 2005. Expression profiling in the aging brain: a perspective. Ageing Res Rev 4:529-547.
-
(2005)
Ageing Res Rev
, vol.4
, pp. 529-547
-
-
Galvin, J.E.1
Ginsberg, S.D.2
-
17
-
-
0033583215
-
Mutant and wild type human α-synucleins assemble into elongated filaments with distinct morphologies in vitro
-
Giasson BI, Uryu K, Trojanowski JQ, Lee VM. 1999. Mutant and wild type human α-synucleins assemble into elongated filaments with distinct morphologies in vitro. J Biol Chem 274:7619-7622.
-
(1999)
J Biol Chem
, vol.274
, pp. 7619-7622
-
-
Giasson, B.I.1
Uryu, K.2
Trojanowski, J.Q.3
Lee, V.M.4
-
18
-
-
15144361589
-
The cDNA cloning and ontogeny of mouse α-synuclein
-
Hong L, Ko HW, Gwag BJ, Joe E, Lee S, Kim YT, Suh YH. 1998. The cDNA cloning and ontogeny of mouse α-synuclein. Neuroreport 9:1239-1243.
-
(1998)
Neuroreport
, vol.9
, pp. 1239-1243
-
-
Hong, L.1
Ko, H.W.2
Gwag, B.J.3
Joe, E.4
Lee, S.5
Kim, Y.T.6
Suh, Y.H.7
-
19
-
-
0028985267
-
The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system
-
Iwai A, Masliah E, Yoshimoto M, Ge N, Flanagan L, de Silva HA, Kittel A, Saitoh T. 1995. The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system. Neuron 14:467-475.
-
(1995)
Neuron
, vol.14
, pp. 467-475
-
-
Iwai, A.1
Masliah, E.2
Yoshimoto, M.3
Ge, N.4
Flanagan, L.5
de Silva, H.A.6
Kittel, A.7
Saitoh, T.8
-
20
-
-
2942555022
-
Structure of membrane-bound α-synuclein studied by site-directed spin labeling
-
Jao CC, Der-Sarkissian A, Chen J, Langen R. 2004. Structure of membrane-bound α-synuclein studied by site-directed spin labeling. Proc Nad Acad Sci U S A 101:8331-8336.
-
(2004)
Proc Nad Acad Sci U S A
, vol.101
, pp. 8331-8336
-
-
Jao, C.C.1
Der-Sarkissian, A.2
Chen, J.3
Langen, R.4
-
21
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, Kosel S, Przuntek H, Epplen JT, Schols L, Riess O. 1998. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nat Genet 18:106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
22
-
-
0344305371
-
Morphogenesis of Lewy bodies: Dissimilar incorporation of α-synuclein, ubiquitin, and p62
-
Kuusisto E, Parkkinen L, Alafuzoff I. 2003. Morphogenesis of Lewy bodies: dissimilar incorporation of α-synuclein, ubiquitin, and p62. J Neuropathol Exp Neurol 62:1241-1253.
-
(2003)
J Neuropathol Exp Neurol
, vol.62
, pp. 1241-1253
-
-
Kuusisto, E.1
Parkkinen, L.2
Alafuzoff, I.3
-
23
-
-
0037016741
-
Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
-
Lee HJ, Choi C, Lee SJ. 2002. Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form. J Biol Chem 277:671-678.
-
(2002)
J Biol Chem
, vol.277
, pp. 671-678
-
-
Lee, H.J.1
Choi, C.2
Lee, S.J.3
-
24
-
-
0034193399
-
Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons
-
Murphy DD, Rueter SM, Trojanowski JQ, Lee VM. 2000. Synucleins are developmentally expressed, and α-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons. J Neurosci 20:3214-3220.
-
(2000)
J Neurosci
, vol.20
, pp. 3214-3220
-
-
Murphy, D.D.1
Rueter, S.M.2
Trojanowski, J.Q.3
Lee, V.M.4
-
25
-
-
0036020651
-
The genetics of aging - implications for pharmacogenomics
-
Perls T, Puca A. 2002. The genetics of aging - implications for pharmacogenomics. Pharmacogenomics 3:469-484.
-
(2002)
Pharmacogenomics
, vol.3
, pp. 469-484
-
-
Perls, T.1
Puca, A.2
-
26
-
-
0038349415
-
Genetics of exceptional longevity
-
Perls T, Terry D. 2003. Genetics of exceptional longevity. Exp Gerontol 38:725-730.
-
(2003)
Exp Gerontol
, vol.38
, pp. 725-730
-
-
Perls, T.1
Terry, D.2
-
27
-
-
0034602271
-
Interaction of human α-synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis
-
Perrin RJ, Woods WS, Clayton DF, George JM. 2000. Interaction of human α-synuclein and Parkinson's disease variants with phospholipids. Structural analysis using site-directed mutagenesis. J Biol Chem 275: 34393-34398.
-
(2000)
J Biol Chem
, vol.275
, pp. 34393-34398
-
-
Perrin, R.J.1
Woods, W.S.2
Clayton, D.F.3
George, J.M.4
-
28
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL. 1997. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
29
-
-
0141957335
-
Quantifying mRNA in postmortem human brain: Influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance
-
Preece P, Cairns NJ. 2003. Quantifying mRNA in postmortem human brain: influence of gender, age at death, postmortem interval, brain pH, agonal state and inter-lobe mRNA variance. Brain Res Mol Brain Res 118:60-71.
-
(2003)
Brain Res Mol Brain Res
, vol.118
, pp. 60-71
-
-
Preece, P.1
Cairns, N.J.2
-
30
-
-
0043021953
-
An optimistic view for quantifying mRNA in post-mortem human brain
-
Preece P, Virley DJ, Costandi M, Coombes R, Moss SJ, Mudge AW, Jazin E, Cairns NJ. 2003. An optimistic view for quantifying mRNA in post-mortem human brain. Brain Res Mol Brain Res 116:7-16.
-
(2003)
Brain Res Mol Brain Res
, vol.116
, pp. 7-16
-
-
Preece, P.1
Virley, D.J.2
Costandi, M.3
Coombes, R.4
Moss, S.J.5
Mudge, A.W.6
Jazin, E.7
Cairns, N.J.8
-
31
-
-
0038404962
-
Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced parkinsonism in mice
-
Schluter OM, Fornai F, Alessandri MG, Takamori S, Geppert M, Jahn R, Sudhof TC. 2003. Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced parkinsonism in mice. Neuroscience 118:985-1002.
-
(2003)
Neuroscience
, vol.118
, pp. 985-1002
-
-
Schluter, O.M.1
Fornai, F.2
Alessandri, M.G.3
Takamori, S.4
Geppert, M.5
Jahn, R.6
Sudhof, T.C.7
-
32
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M. 1998. α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci U S A 95:6469-6473.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
33
-
-
0038727850
-
Parkinson's disease and related α-synucleinopathies are brain amyloidoses
-
Trojanowski JQ, Lee VM. 2003. Parkinson's disease and related α-synucleinopathies are brain amyloidoses. Ann N Y Acad Sci 991:107-110.
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 107-110
-
-
Trojanowski, J.Q.1
Lee, V.M.2
-
34
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda K, Fukushima H, Masliah E, Xia Y, Iwai A, Yoshimoto M, Otero DA, Kondo J, Ihara Y, Saitoh T. 1993. Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci U S A 90:11282-11286.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
35
-
-
0028618190
-
Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid
-
Ueda K, Saitoh T, Mori H. 1994. Tissue-dependent alternative splicing of mRNA for NACP, the precursor of non-A beta component of Alzheimer's disease amyloid. Biochem Biophys Res Commun 205:1366-1372.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1366-1372
-
-
Ueda, K.1
Saitoh, T.2
Mori, H.3
-
36
-
-
0029904487
-
NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded
-
Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT Jr. 1996. NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded. Biochemistry 35:13709-13715.
-
(1996)
Biochemistry
, vol.35
, pp. 13709-13715
-
-
Weinreb, P.H.1
Zhen, W.2
Poon, A.W.3
Conway, K.A.4
Lansbury Jr., P.T.5
|