A novel method for biodosimetry

Radiation and Environmental Biophysics

Volumn 46, Issue 2, 2007, Pages 147-154

  Megid, Wael Abdel ^a,b   Ensenberger, Martin G ^b   Halberg, Richard B ^c   Stanhope, Stephen A ^d   Kent First, Marijo G ^e   Prolla, Tomas A ^a   Bacher, Jeff W ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b PROMEGA CORPORATION   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d University of Wisconsin Madison   (United States)

^e MISSISSIPPI STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODOSIMETRY; BIOLOGICAL EFFECTS; GENETIC DAMAGE; RADIATION EXPOSURE;

BIOMARKERS; DNA SEQUENCES; GENES; MOLECULAR DYNAMICS; RADIATION EFFECTS; RISK ANALYSIS;

DOSIMETERS;

CESIUM 137; IRON;

ANALYTIC METHOD; CONFERENCE PAPER; CONTROLLED STUDY; DNA DAMAGE; DNA SCREENING; DNA SEQUENCE; DOSIMETRY; FEASIBILITY STUDY; GAMMA RADIATION; GENE MUTATION; GENETIC DAMAGE; GENOME; HUMAN; HUMAN CELL; MALE; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY; Y CHROMOSOME;

BIOLOGICAL ASSAY; DNA; DNA MUTATIONAL ANALYSIS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEASIBILITY STUDIES; MICROSATELLITE REPEATS; RADIATION DOSAGE; RADIOMETRY; SEQUENCE ANALYSIS, DNA;

EID: 34248158902     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00411-006-0072-1     Document Type: Conference Paper

References (18)

1. Durante M (2005) Biomarkers of space radiation risk. Radiat Res 164:467-473
2. Kleinerman RA, Romanyukha AA, Schauer DA, Tucker JD (2006) Retrospective assessment of radiation exposure using biological dosimetry: chromosome painting, electron paramagnetic resonance and the glycophorin a mutation assay. Radiat Res 166:287-302
3. Bouffler SD, Bridges BA, Cooper DN, Dubrova Y, McMillan TJ, Thacker J, Wright EG, Waters R (2006) Assessing radiation-associated mutational risk to the germline: repetitive DNA sequences as mutational targets and biomarkers. Radiat Res 165:249-268
4. Dubrova YE (2005) Radiation-induced mutation at tandem repeat DNA Loci in the mouse germline: spectra and doubling doses. Radiat Res 163:200-207
5. Yauk CL, Dubrova YE, Grant GR, Jeffreys AJ (2002) A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus. Mutat Res 500:147-156
6. Boyd M, Livingstone A, Wilson LE, Marshall EM, McCluskey AG, Mairs RJ, Wheldon TE (2000) Dose-response relationship for radiation-induced mutations at micro- and minisatellite loci in human somatic cells in culture. Int J Radiat Biol 76:169-176
7. Bacher JW, Flanagan LA, Smalley RL, Nassif NA, Burgart LJ, Halberg RB, Megid WM, Thibodeau SN (2004) Development of a fluorescent multiplex assay for detection of MSI-high tumors. Dis Markers 20:237-250
8. Bacher JW, Abdel Megid WM, Kent-First MG, Halberg RB (2005) Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumors. Mol Carcinog 44:285-292
9. Budowle B, Adamowicz M, Aranda XG, Barna C, Chakraborty R, Cheswick D, Dafoe B, Eisenberg A, Frappier R, Gross AM, Ladd C, Lee HS, Milne SC, Meyers C, Prinz M, Richard ML, Saldanha G, Tierney AA, Viculis L, Krenke BE (2005) Twelve short tandem repeat loci Y chromosome haplotypes: genetic analysis on populations residing in North America. Forensic Sci Int 150:1-15
10. Butler JM (2006) Genetics and genomics of core short tandem repeat loci used in human identity testing. J Forensic Sci 51:253-265
11. Birioukov A, Meurer M, Peter RU, Braun-Falco O, Plewig G (1993) Male reproductive system in patients exposed to ionizing irradiation in the Chernobyl accident. Arch Androl 30:99-104
12. Tilford CA, Kuroda-Kawaguchi T, Skaletsky H, Rozen S, Brown LG, Rosenberg M, McPherson JD, Wylie K, Sekhon M, Kucaba TA, Waterston RH, Page DC (2001) A physical map of the human Y chromosome. Nature 409:943-945
13. Coolbaugh-Murphy M, Maleki A, Ramagli L, Frazier M, Lichtiger B, Monckton D G, Siciliano MJ, Brown BW (2004) Estimating mutant microsatellite allele frequencies in somatic cells by small-pool PCR. Genomics 84:419-430
14. Zhang Y, Monckton DG, Siciliano MJ, Connor TH, Meistrich ML (2002) Detection of radiation and cyclophosphamide-induced mutations in individual mouse sperm at a human expanded trinucleotide repeat locus transgene. Mutat Res 516:121-138
15. Chang PY, Kanazawa N, Lutze-Mann L, Winegar RA (2001) p53 deficiency alters the yield and spectrum of radiation-induced lacZ mutants in the brain of transgenic mice. Mutagenesis 16:7-15
16. Kumar PR, Mohankumar MN, Hamza VZ, Jeevanram RK (2006) Dose-rate effect on the induction of HPRT mutants in human G0 lymphocytes exposed in vitro to gamma radiation. Radiat Res 165:43-50
17. Durante M, Snigiryova G, Akaeva E, Bogomazova A, Druzhinin S, Fedorenko B, Greco O, Novitskaya N, Rubanovich A, Shevchenko V, Von Recklinghausen U, Obe G (2003) Chromosome aberration dosimetry in cosmonauts after single or multiple space flights. Cytogenet Genome Res 103:40-46
18. Armour JA (2006) Tandemly repeated DNA: why should anyone care? Mutat Res 598:6-14