A modified approach for I-FISH evaluation of ERBB2 (HER-2) gene copy numbers in breast carcinomas: Comparison with HER-2/CEP17 ratio system

Journal of Cancer Research and Clinical Oncology

Volumn 133, Issue 5, 2007, Pages 321-329

  Mrhalova, Marcela ^a   Kodet, Roman ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

Author keywords

Breast carcinoma; ERBB2 gene amplification; HER 2; I FISH evaluation

Indexed keywords

PARAFFIN; TRASTUZUMAB;

ARTICLE; BREAST CARCINOMA; CONTROLLED STUDY; DNA PROBE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE NUMBER; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; ONCOGENE NEU; PRIORITY JOURNAL; TUMOR CELL;

BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; GENE DOSAGE; GENES, ERBB-2; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; RECEPTOR, ERBB-2;

EID: 34248148099     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00432-006-0175-8     Document Type: Article

References (13)

1. Adeyinka A, Mertens F, Idvall I, Bondeson L, Pandis N (1999) Multiple polysomies in breast carcinomas: preferential gain of chromosomes 1, 5, 6, 7, 12, 16, 17, 18, and 19. Cancer Genet Cytogenet 111(2):144-148
2. Aubele M, Mattis A, Zitzelsberger H, Walch A, Kremer M, Hutzler P, Hofler H, Werner M (1999) Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization. Cancer Genet Cytogenet 110(2):94-102
3. Fernandez JL, Goyanes V, Lopez-Fernandez C, Buno I, Gosalvez J (1996) Quantification of C-ERB-B2 gene amplification in breast cancer cells using fluorescence in situ hybridization and digital image analysis. Cancer Genet Cytogenet 86(1):18-21
4. Ginestier C, Charafe-Jauffret E, Penault-Llorca F, Geneix J, Adelaide J, Chaffanet M, Mozziconacci MJ, Hassoun J, Viens P, Birnbaum D, et al (2004) Comparative multi-methodological measurement of ERBB2 status in breast cancer. J Pathol 202(3):286-298
5. Hicks DG, Tubbs RR (2005) Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: a technical review with interpretive guidelines. Hum Pathol 36(3):250-261
6. Hoang MP, Sahin AA, Ordonez NG, Sneige N (2000) HER-2/neu gene amplification compared with HER-2/neu protein overexpression and interobserver reproducibility in invasive breast carcinoma. Am J Clin Pathol 113(6):852-859
7. Klijanienko J, Couturier J, Galut M, El-Naggar AK, Maciorowski Z, Padoy E, Mosseri V, Vielh P (1999) Detection and quantitation by fluorescence in situ hybridization (FISH) and image analysis of HER-2/neu gene amplification in breast cancer fine-needle samples. Cancer 87(5):312-318
8. Lebeau A, Deimling D, Kaltz C, Sendelhofert A, Iff A, Luthardt B, Untch M, Lohrs U (2001) Her-2/neu analysis in archival tissue samples of human breast cancer: comparison of immunohistochemistry and fluorescence in situ hybridization. J Clin Oncol 19(2):354-363
9. Marinho AF, Botelho M, Schmitt FC (2000) Evaluation of numerical abnormalities of chromosomes 1 and 17 in proliferative epithelial breast lesions using fluorescence in situ hybridization. Pathol Res Pract 196(4):227-233
10. Mendelin J, Grayson M, Wallis T, Visscher DW (1999) Analysis of chromosome aneuploidy in breast carcinoma progression by using fluorescence in situ hybridization. Lab Invest 79(4):387-393
11. Pauletti G, Godolphin W, Press MF, Slamon DJ (1996) Detection and quantitation of HER-2/neu gene amplification in human breast cancer archival material using fluorescence in situ hybridization. Oncogene 13(1):63-72
12. Pellikainen J, Naukkarinen A, Ropponen K, Rummukainen J, Kataja V, Kellokoski J, Eskelinen M, Kosma V-M (2004) Expression of HER2 and its association with AP-2 in breast cancer. Eur J Cancer 40:1485-1495
13. Tsuda H, Akiyama F, Terasaki H, Hasegawa T, Kurosumi M, Shimadzu M, Yamamori S, Sakamoto G (2001) Detection of HER-2/neu (c-erb B-2) DNA amplification in primary breast carcinoma. Interobserver reproducibility and correlation with immunohistochemical HER-2 overexpression. Cancer 92(12):2965-2974