Quantification of C-ERB-B2 gene amplification in breast cancer cells using fluorescence in situ hybridization and digital image analysis

Cancer Genetics and Cytogenetics

Volumn 86, Issue 1, 1996, Pages 18-21

  Fernández, José Luis ^a   Goyanes, Vicente ^b   López Fernández, Carmen ^c   Buño, Ismael ^c   Gosálvez, Jaime ^c  

^a Centro Oncologico de Galicia   (Spain)

^b Hospital Teresa Herrera   (Spain)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; ONCOGENE C ERB; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS;

EID: 0029670101     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/0165-4608(95)00176-X     Document Type: Article

References (15)

1. Solomon E, Borrow J, Goddard AD (1991): Chromosome aberrations and cancer. Science 254:1153-1160.
2. Sandberg AA (1990): The Chromosomes in Human Cancer and Leukemia, 2nd Edition. Elsevier, New York.
3. Trask BJ, Hamlin JL (1989): Early dihydrofolate reductase gene amplification events in CHO cells usually occur on the same chromosome arm as the original locus. Genes Dev 3: 1913-1925.
4. Ruiz JC, Wahl GM (1990): Chromosomal destabilization during gene amplification. Mol Cel Biol 10:3056-3066.
5. Smith KA, Stark MB, Gorman PA, Stark GR (1992): Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells. Proc Natl Acad Sci USA 89: 5427-5431.
6. Le Roy X, Escot C, Brouillet JP, Theillet C, Maudelonde T, Simony-Lafontaine J, Pujol H, Rochefort H (1991): Decrease of c-erbB 2 and c-myc RNA levels in tamoxifen-treated breast cancer. Oncogene 6:431-437.
7. Charpin C, Andrac L, Devictor B, Habib M, Lavaut MN, Allasia C, Bonnier P, Piana L (1993): Digital image analysis of nuclear morphology, DNA ploidy and Ag-NORs in breast carcinoma cell imprints. Int J Oncol 3:949-956.
8. Ofner D, Hittmair A, Marth C, Totsch M, Daxenbichler G, Margreiter R, Bocher W, Smith KW (1993): Relationship between quantity of silver stained nucleolar organiser region associated proteins (Ag-NORs) and growth rate suppression of breast cancer cell lines after interferon-gamma and 4-hydroxy-tamoxifen treatment. Virch B Cell Path 63:359-363.
9. Kallionemi OP, Kallionemi A, Kurisu W, Thor A, Chen L-C, Smith HS, Waldman FM, Pinkel D, Gray JW (1992): ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization. Proc Natl Acad Sci USA 89:5321-5325.
10. Shapiro DN, Valentine MB, Rowe ST, Sinclair AE, Sublett JE, Roberts WM, Look AT (1993): Detection of N-myc gene amplification by fluorescence in situ hybridization. Am J Pathol 142:1339-1346.
11. Sauter G, Moch H, Moore D, Carroll P, Kerschmann R, Chew K, Mihatsch MJ, Gudat F, Waldman F (1993): Heterogeneity of erbB2 gene amplification in bladder cancer. Cancer Res 53:2199-2203.
12. Goyanes VJ (1985): Staining, recognition and ultrastructure of the human Y chromosome. In Sandberg AA (ed). The Y Chromosome, Part A: Basic Characteristics of the Y Chromosome. Alan R Liss, New York, pp. 303-316.
13. Noesis (1992): Visilog 4. Reference Guide. Vélize, France, Noesis.
14. Perren TJ (1991): C-erb B-2 oncogene as a prognostic marker in breast cancer. Br J Cancer 63:328-332.
15. Thompson AM (1994): Breast cancer. In: Cancer, a Molecular Approach. Lemoine N, Neoptolemos J, Cooke T (eds). Blackwell, Oxford, pp. 163-183.