Detection of Treponema pallidum in the vitreous by PCR

British Journal of Ophthalmology

Volumn 91, Issue 5, 2007, Pages 592-595

  Muller M ^a   Ewert, I ^a   Hansmann, F ^a   Tiemann, C ^b   Hagedorn, H J ^b   Solbach, W ^a   Roider, J ^c   Nolle B ^c   Laqua, H ^a   Hoerauf, H ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b Medical Examination Center   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIBIOTIC AGENT; ANTIVIRUS AGENT; CARDIOLIPIN; CEFTRIAXONE; FOSCARNET; PREDNISOLONE; PREDNISONE; VALACICLOVIR;

ACUTE DISEASE; ADULT; AGED; ANAMNESIS; ARTICLE; BLURRED VISION; CASE REPORT; CHORIORETINITIS; CLINICAL FEATURE; ENDOTHELIUM CELL; EYE EXAMINATION; FOLLOW UP; HUMAN; KIRISAWA UVEITIS; LABORATORY TEST; MALE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RETINITIS; TREATMENT DURATION; TREATMENT FAILURE; TREPONEMA PALLIDUM; VISUAL ACUITY; VITRECTOMY; VITREOUS BODY;

ADULT; AGED; EYE INFECTIONS, BACTERIAL; HUMANS; MALE; POLYMERASE CHAIN REACTION; SYPHILIS; TREPONEMA PALLIDUM; VITREOUS BODY;

EID: 34248144862     PISSN: 00071161     EISSN: None     Source Type: Journal    
DOI: 10.1136/bjo.2006.110288     Document Type: Article

References (19)

1. Gass JDM, Braunstein RA, Chenoweth RG. Acute syphilitic posterior placoid chorioretinitis. Ophthalmology 1990;97:1288-97.
2. Arruga J, Valentines J, Mauri F, et al. Neuroretinitis in acquired syphilis. Ophthalmology 1985;92:262-70.
3. Folk JC, Weingeist TA, Corbett JJ, et al. Syphilitic neuroretinitis. Am J Ophthalmol 1983;95:480-6.
4. Mora P, Borruat F-X, Guex-Crosier Y. Indocyanine green angiography anomalies in ocular syphilis. Retina 2005;25:171-81.
5. Aldave AJ, King JA, Cunningham ET Jr. Ocular syphilis. Curr Opin Ophthalmol 2001;12:433-41.
6. Woznicova V, Heroldova M. Direct detection of Treponema pallidum in diagnosis of syphilis. Epidemiol Mikrobiol Immunol 2004;53:121-5.
7. Burstain JM, Grimprel E, Lukehart SA, et al. Sensitive detection of Treponema pallidum by using the polymerase chain reaction. J Clin Microbiol 1991;29:62-9.
8. Noordhoek GT, Wolters EC, de Jonge ME, et al. Detection by polymerase chain reaction of Treponema pallidum DNA in cerebrospinal fluid from neurosyphilis patients before and after antibiotic treatment. J Clin Microbiol 1991;29:1976-84.
9. Palmer HM, Higgins SP, Herring AJ, et al. Use of PCR in the diagnosis of early syphilis in the United Kingdom. Sex Transm Infect 2003;79:479-83.
10. Liu H, Rodes B, Chen CY, et al. New tests for syphilis: rational design of a PCR method for detection of Treponema pallidum in clinical specimens using unique regions of the DNA polymerase I gene. J Clin Microbiol 2001;39:1941-6.
11. Centurion-Lara A, Castro C, Shaffer JM, et al. Detection of Treponema pallidum by a sensitive reverse transcriptase PCR. J Clin Microbiol 1997;35:1348-52.
12. Inagaki H, Kawai T, Miyata M, et al. Gastric syphilis: polymerase chain reaction detection of treponemal DNA in pseudolymphomatous lesions. Hum Pathol 1996;27:761-5.
13. Smith JL, Israel CW. Spirochetes in the aqueous humor in seronegative ocular syphilis. Persistence after penicillin therapy. Arch Ophthalmol 1967;77:474-7.
14. Grimprel E, Sanchez PJ, Wendel GD, et al. Use of polymerase chain reaction and rabbit infectivity testing to detect Treponema pallidum in amniotic fluid, fetal and neonatal sera and cerebrospinal fluid. J Clin Microbiol 1991;29:1711-78.
15. Bruckbauer HR, Preac-Mursic V, Fuchs R, et al. Cross-reactive proteins of Borrelia burgdorferi. Eur J Clin Microbiol Infect Dis 1992;1:224-32.
16. Pietravalle M, Pimpinelli F, Maini A, et al. Diagnostic relevance of polymerase chain reaction technology for T. pallidum in subjects with syphilis in different phases of infection. New Microbiol 1999;22:99-104.
17. Zoechling N, Schluepen EM, Soyer HP, et al. Molecular detection of Treponema pallidum in secondary and tertiary syphilis. Br J Dermatol 1997;136:683-6.
18. Radolf JD. PCR detection of treponema pallidum. In: Persing DH, et al, eds. Diagnostic molecular microbiology. Blackwell Publishing, Washington, DC, 1993:224-9.
19. Van Gelder RN. Applications of the polymerase chain reaction to diagnosis of ophthalmic disease. Surv Ophthalmol 2001;46:248-58.