HLA-A, -B, -C, and -DRB1 allele frequencies in Cuban individuals with antecedents of dengue 2 disease: Advantages of the Cuban population for HLA studies of dengue virus infection

Human Immunology

Volumn 68, Issue 6, 2007, Pages 531-540

  Sierra, Beatriz ^a   Alegre, Roberto ^a   Pérez, Ana B ^a   García, Gissel ^a   Sturn Ramirez, Katharina ^b   Obasanjo, Olugbenga ^b   Aguirre, Eglys ^a   Alvarez, Mayling ^a   Rodriguez Roche, Rosmari ^a   Valdés, Luis ^a   Kanki, Phyllis ^b   Guzmán, María G ^a  

^a INSTITUTO DE MEDICINA TROPICAL PEDRO KOURÍ   (Cuba)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Cuban dengue history; dengue; Human leukocyte antigen

Indexed keywords

HLA A ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA B ANTIGEN; HLA C ANTIGEN; HLA DR ANTIGEN;

ADULT; ARTICLE; CONTROLLED STUDY; CUBA; DENGUE; DISEASE PREDISPOSITION; DISEASE RESISTANCE; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HEREDITY; HLA TYPING; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PRIORITY JOURNAL;

ADULT; CUBA; DENGUE; DENGUE VIRUS; FEMALE; GENE FREQUENCY; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-C ANTIGENS; HLA-DR ANTIGENS; HUMANS; MALE; MIDDLE AGED;

EID: 34248140776     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2007.03.001     Document Type: Article

References (83)

1. Monath T.P. Dengue: the risk to developed and developing countries. Proc Natl Acad Sci USA 91 (1994) 2395
2. World Health Organization (WHO). Dengue Hemorrhagic Fever. Diagnosis, Treatment, Prevention and Control. 2nd ed. (1997), WHO, Geneva
3. Vaughn D.W., Green S., Kalayanarooj S., Innis B.L., Nimmannitya S., Suntayakorn S., Endy T.P., Raengsakulrach B., Rothman A.L., Ennis S.A., and Nisalak A. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J Infect Dis 181 (2000) 2
4. Halstead S.B., Nimmannitya S., and Cohen S.N. Observations related to pathogenesis of dengue hemorrhagic fever. IV. Relation of disease severity to antibody response and virus recovered. Yale J Biol Med 42 (1970) 311
5. Halstead S. Antibody, macrophages, dengue virus infection, shock, and hemorrhage: a pathogenetic cascade. Rev Infect Dis 11 (1989) S830
6. Rothman A.L., and Ennis F.A. Immunopathogenesis of dengue hemorrhagic fever. Virology 257 (1999) 1
7. Guzman M.G., and Kouri G. Dengue and dengue hemorrhagic fever in the Americas: lessons and challenges. J Clin Virol 27 (2003) 1
8. Burke D.S., Nisalak A.S., Johnson D.E., and Scott R.M. A prospective study of dengue infection in Bangok. Am J Trop Med Hyg 88 (1988) 172
9. Bravo J.R., Guzmán M.G., and Kourí G.P. Why dengue haemorragic fever in Cuba? I. Individual risk factors for dengue haemorragic fever/dengue shock syndrome (DHF/DSS). Trans R Soc Trop Med Hyg 81 (1987) 816
10. Guzman M.G., Kourí G.P., Bravo J., Soler M., Vazquez S., and Morier L. Dengue Hemorrhagic Fever in Cuba, 1981: a retrospective seroepidemiologic study. Am J Med Hyg 42 (1990) 179
11. Guzman M.G., Kouri G.P., Vazquez S., Rosario D., Bravo J.R., and Valdez L. DHF Epidemics in Cuba, 1981 and 1997. some interesting observations. Dengue Bulletin (1999), World Health Organization 23
12. Kourí G., Guzmén M.G., Valdés L., Carbonel I., Rosario D., Vázquez S., Laferté J., Delgado J., and Cabrera M.V. Reemergence of dengue in Cuba: a 1997 epidemic in Santiago de Cuba. Emerg Inf Dis 4 (1998) 89
13. Valdés L., Guzmán M.G., Kourí G., Delgado J., Carbonell I., Cabrera M.V., Rosario D., and Vazquez S. The epidemiology of dengue and dengue hemorrhagic fever in Santiago de Cuba. Pan Am J Public Health 6 (1997) 16
14. Guzmén M.G., Kouré G., Valdéz L., Bravo J., Álvarez M., Vázquez S., Delgado I., and Halstead S.B. Epidemiological studies of dengue in Santiago de Cuba 1997. Am J Epidemiol 152 (2000) 793
15. Pelaez O., Guzman M.G., Kouri G., Perez R., San Martin J.L., Vazquez S., Rosario D., Mora R., Quintana I., Bisset J., Cancio R., Masa A.M., Castro O., Gonzalez D., Avila L.C., Rodriguez R., Alvarez M., Pelegrino J.L., Bernardo L., and Prado I. Dengue 3 epidemic, Havana, 2001. Emerg Infect Dis 10 (2004) 719
16. Chiewsilp P., Scott R.M., and Bhamarapravati N. Histocompatibility antigens and dengue hemorrhagic fever. Am J Trop Med Hyg 30 (1981) 1100
17. Paradoa Perez M.L., Trujillo Y., and Basanta P. Association of dengue hemorrhagic fever with the HLA system. Haematologia 20 (1987) 83
18. Stephens H.A.F., Klaythong R., Sirikong M., Vaughn D.W., Green S., Kalayanarooj S., Endy T.P., Libraty D.H., Nisalak A., Innis B.L., Rothman A.L., Ennis F.A., and Chandanayingyong D. HLA-A and -B allele associations with secondary dengue virus infections correlate M. Sirikong with disease severity and the infecting viral serotype in ethnic Thais. Tissue Antigens 60 (2002) 309
19. LaFleur C., Granados J., Vargas-Alarcon G., Ruiz-Morales J., Villarreal-Garza C., Higuera L., Hernandez-Pacheco G., Cutino-Moguel T., Rangel H., Figueroa R., Acosta M., Lazcano E., and Ramos C. HLA-DR antigen frequencies in Mexican patients with dengue virus infection: HLA-DR4 as a possible genetic resistance factor for dengue hemorrhagic fever. Hum Immunol 63 (2002) 1039
20. Loke H., Bethell D.B., Phuong C.X., Dung M., Schneider J., White N.J., Day N.P., Farrar J., and Hill A.V. Strong HLA class I-restricted T cell responses in dengue hemorrhagic fever: a double-edged sword?. J Infect Dis 184 (2001) 1369
21. Loke H., Bethell D., Phuong C.X., Day N., White N., Farrar J., and Hill A. Susceptibility to dengue hemorrhagic fever in vietnam: evidence of an association with variation in the vitamin d receptor and Fc gamma receptor IIa genes. Am J Trop Med Hyg 67 (2002) 1
22. Gubler D.J. Dengue and dengue hemorrhagic fever: its history and resurgence as a global public health problem. In: Gubler D.J., and Kuno G. (Eds). Dengue and dengue hemorrhagic fever (1997), CAB International Press, New York Chapter 13
23. Arias J. Dengue in Cuba. Bull Pan Am Health Org 11 (2000) 2
24. Green M.M. Fighting dengue in Cuba. Science 277 (1997) 623
25. Spiegel J., Yassi A., and Tate R. Dengue in Cuba: mobilisation against Aedes aegypti. Lancet Infect Dis 2 (2000) 207
26. Perez A.B., Garcia G., Sierra B., Alvarez M., Vazquez S., Cabrera M.V., Rodriguez R., Rosario D., Martinez E., Denny T., and Guzman M.G. IL-10 levels in dengue patients: some findings from the exceptional epidemiological conditions in Cuba. J Med Virol 73 (2004) 230
27. Sierra B., Garcia G., Perez A.B., Morier L., Rodriguez R., Alvarez M., and Guzman M.G. Long-term memory cellular immune response to dengue virus after a natural primary infection. Int J Infect Dis 6 (2002) 125
28. Guzman M.G., Kouri G., Bravo J., Valdes L., Vazquez S., and Halstead S.B. Effect of age on outcome of secondary dengue 2 infections. Int J Infect Dis 6 (2002) 118
29. Guzman M.G., Kouri G., Valdes L., Bravo J., Vazquez S., and Halstead S.B. Enhanced severity of secondary dengue-2 infections: death rates in 1981 and 1997 Cuban outbreaks. Bull Pan Am Health Org 11 (2002) 223
30. Vargas Caballero M.E., Aguirre Portuondo T.M., and Palacios Serrano H. Clinical features of dengue fever in children during the outbreak in Santiago de Cuba. Rev Cubana Med Trop 53 (2001) 20
31. Vaughn D.W. Invited commentary: dengue lessons from Cuba. Am J Epidemiol 152 (2000) 793
32. Guzman M.G., Kouri G., and Halstead S.B. Do escape mutants explain rapid increases in dengue case-fatality rates within epidemics?. Lancet 355 (2000) 1902
33. Rammensee H., Bachmann J., Emmerich N.P., Bachor O.A., and Stevanovic S. SYFPEITHI: database for MHC ligands and peptide motifs. Immunogenetics 50 (1999) 213
34. Parker K.C., Bednarek M.A., and Coligan J.E. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains. J Immunol 152 (1994) 163
35. Dengue and dengue hemorraghic fever in the Americas. guidelines for prevention and control (1994), Pan American Health Organization, Washington Scientific publication No. 548
36. Vazquez S., Saenz E., Huelva G., Gonzalez A., Kouri G., and Guzman M. Detection of IgM against the dengue++ virus in whole blood absorbed on filter paper. Pan Am J Public Health 3 (1998) 174
37. Laferte J., Pelegrino J.L., Guzmán M.G., González G., Vázquez S., and Hermida C. Rapid diagnosis of dengue virus infection using a novel 10μl IgM antibody capture ultramicroELISA assay (MAC UMELISA Dengue). Advances Mod Biotechnol 1 (1992) 19
38. Lanciotti R.S., Calisher C.H., Gubler D.G., Chang G., and Vordam V. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 30 (1992) 545
39. Rodriguez-Roche R., Alvarez M., Gritsun T., Rosario D., Halstead S., Kouri G., Gould E.A., and Guzman M.G. Dengue virus type 2 in Cuba, 1997: conservation of E gene sequence in isolates obtained at different times during the epidemic. Arch Virol 150 (2004) 415
40. Morens M.D., Halstead S.B., Repic P.M., Putvatana R., and Raybourne N. Simplified plaque reduction neutralization assay for dengue viruses by semimicro methods in BHK-21 cells. Comparison of the BHK suspension test whit standard plaque reduction neutralization. J Clin Microb 22 (1985) 250
41. ASHI. 1998 ASHI Standards for Histocompatibility Testing, 1998 Membership Directory, American Society for Histocompatibility and Immunogenetics, Lenexa, Kansas, 1998.
42. Schneider S., Roessli D., and Excofier L. Arlequin: a software for population genetics data analysis, Ver 2.000 (2000), Genetics and Biometry Laboratory, Department of Anthropology, University of Geneva, Geneva. http://lgb.unige.ch/arlequin/ http://lgb.unige.ch/arlequin/.
43. Haldane J.B.S. The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet 20 (1956) 308
44. Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet 19 (1955) 251
45. Bland J.M., and Altman D.G. Multiple significance tests: the Bonferroni method. Br Med J 310 (1995) 170
46. Clayton J., and Lonjou C. Allele and haplotype frequencies for HLA loci in various ethnic groups. In: Charron D. (Ed). HLA: Genetic Diversity of HLA Functional and Medical Implication (1997), EDK Medical and International Publisher, Paris, France 665 Proceedings of the Twelfth International Histocompatibility Workshop, Vol. 1
47. The on-line 13th International Histocompatibility Workshop allele frequencies database. Available at: http://www.ncbi.nlm.nih/mhc/ihwg.fcgi.
48. Kalayanarooj S., Vaughn D.W., Nimmannitya S., Green S., Suntayakorn S., Kunentrasai N., Viramitrachai W., Ratanachu-eke S., Kiatpolpoj S., Innis B.L., Rothman A.L., Nisalak A., and Ennis F.A. Early clinical and laboratory indicators of acute dengue illness. J Infect Dis 176 (1997) 313
49. Vaughn D.W., Green S., Kalayanarooj S., Innis B.L., Nimmannitya S., Suntayakorn S., Rothman A.L., Ennis F.A., and Nisalak A. Dengue in the early febrile phase: viremia and antibody responses. J Infect Dis 176 (1997) 322
50. Guzman M.G., and Kouri G. Dengue: an update. Lancet Infect Dis 2 (2002) 33
51. Guerra R. Manual de Historia de Cuba desde su Descubrimiento. Colección Histórica, Editorial Nacional de Cuba, C. Habana (1964)
52. Guanche J. Procesos Etno-Culturales de Cuba, La Habana, Editorial de Letras Cubanas (1983)
53. Guzman M., Kouri G., Diaz M., Llop A., Vazquez S., Gonzalez D., Castro O., Alvarez A., Fuentes O., Montada D., Padmanabha H., Sierra B., Perez A., Rosario D., Pupo M., Diaz C., and Sanchez L. Dengue, one of the great emerging health challenges of the 21st century. Expert Rev Vaccines 3 (2004) 511
54. Halstead S.B. Epidemiology of dengue and dengue hemorrhagic fever. In: Gubler D.J., and Kuno G. (Eds). Dengue and Dengue Hemorrhagic Fever (1997), CAB International Press, New York
55. Rothman A.L. Viral pathogenesis of dengue infections. In: Gubler D.J., and Kuno G. (Eds). Dengue and Dengue Hemorrhagic Fever (1997), CAB International Press, New York
56. Saxena S., Dash S.C., Guleria S., Mittal R., Agarwal S.K., Tiwari S.C., and Mehta S.N. Post transplant diabetes mellitus in live related renal allograft recipients: a single centre experience. J Assoc Physicians India 44 (1996) 472
57. Winkler C.L., Tucker J.M., Hauth J.C., Goldenberg R.L., Acton R.T., Barger B.O., Go R.C., Bell D.S., Perkins L.L., and Vanichanan C.J. Histocompatibility antigen subtypes in black women with class A1 or class GB diabetes mellitus. Am J Perinatol 8 (1991) 106
58. Kouri G.P., Guzman M.G., Bravo J.R., and Triana C. Dengue haemorrhagic fever/dengue shock syndrome: lessons from the Cuban epidemic, 1981. Bull WHO 67 (1989) 375
59. Takedatsu H., Shichijo S., Katagiri K., Sawamizu H., Sata M., and Itoh K. Identification of peptide vaccine candidates sharing among HLA-A3+, -A11+, -A31+, and -A33+ cancer patients. Clin Cancer Res 10 (2004) 1112
60. Wang R.F., Appella E., Kawakami Y., Kang X., and Rosenberg S.A. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. J Exp Med 184 (1996) 2207
61. Suzuki K., Sahara H., Okada Y., Yasoshima T., Hirohashi Y., Nabeta Y., Hirai I., Torigoe T., Takahashi S., Matsuura A., Takahashi N., Sasaki A., Suzuki M., Hamuro J., Ikeda H., Wada Y., Hirata K., Kikuchi K., and Sato N. Identification of natural antigenic peptides of a human gastric signet ring cell carcinoma recognized by HLA-A31-restricted cytotoxic T lymphocytes. J Immunol 163 (1999) 2783
62. Sahara H., Nabeta Y., Torigoe T., Hirohashi Y., Ichimiya S., Wada Y., Takahashi N., Jimbow K., Yajima T., Watanabe N., Kikuchi K., and Sato N. A gene encoding human gastric signet ring cell carcinoma antigen recognized by HLA-A31-restricted cytotoxic T lymphocytes. J Immunother 25 (2002) 235
63. Takedatsu H., Shichijo S., Azuma K., Takedatsu H., Sata M., and Itoh K. Detection of a set of peptide vaccine candidates for use in HLA-A31+ epithelial cancer patients. Int J Oncol 24 (2004) 337
64. Veronese Rodrigues M.L., de Castro Figueiredo J.F., Deghaide N.H., Romao E., Vieira de Souza N., and Donadi E.A. Frequency of HLA class 1 and 2 alleles in Brazilian patients with AIDS and cytomegalovirus retinitis. Acta Ophthalmol Scand 81 (2003) 514
65. Missale G., Redeker A., Person J., Fowler P., Guilhot S., Schlicht H.J., Ferrari C., and Chisari F.V. HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis. J Exp Med 177 (1993) 751
66. Fanning L.J., Kenny-Walsh E., and Shanahan F. Persistence of hepatitis C virus in a white population: associations with human leukocyte antigen class 1. Hum Immunol 65 (2004) 745
67. Arnaiz-Villena A., Vargas Alarcon G., Granados F., Gomez C., Longas J., Gonzalez Hevilia M., Zuñiga J., Salgado N., Hernandez-Pacheco G., and Martinez-Laso J. HLA genes in Mexican Mazatecans, the peopling of the Americas and the uniqueness of the Amerindians. Tissue Antigens 56 (2002) 40
68. Guerra R. Manual de Historia de Cuba desde su Descubrimiento. Colección Histórica, Editorial Nacional de Cuba, C. Habana (1964)
69. Rivero de la Calle M. Antropología de la Poblaciín Adulta Cubana. Editorial Científico Técnica, Ciudad de La Habana, 1984, 44.
70. Centro de Estudios Demográficos Cubanos. La Población de Cuba. Editorial Ciencias Sociales, La Habana, 1976.
71. Guanche J. Procesos Etno-Culturales de Cuba, La Habana, Editorial de Letras Cubanas (1983)
72. Chaturvedi U.C., Nagar R., and Shrivastava R. Dengue and dengue hemorrhagic fever: implications of host genetics. FEEMS Immunol Med Microbiol 47 (2006) 155
73. Phoung C.X., Nhan N.T., Kneen R., Pham T.T.T., Chu V.T., Nguyen T.T.N., Tran T.T., Tom S., Kasia S., Bridget W., and DONG NAI Study group. Clinical diagnosis and assessment of severity of confirmed dengue infections in Vietnamese children: is the World Health Organization classification system helpful?. Am J Trop Med Hyg 70 (2004) 459
74. Zivna I., Green S., Vaughn D.W., Kalayanarooj S., Stephens H.A., Chandanayingyong D., Nisalak A., Ennis F.A., and Rothman A.L. T cell responses to an HLA-B*07-restricted epitope on the dengue NS3 protein correlate with disease severity. J Immunol 168 (2002) 5959
75. Mathew A., Kurane I., Green S., Vaughn D.W., Kalayanarooj S., Suntayakorn S., Ennis F.A., and Rothman A.L. Predominance of HLA-restricted cytotoxic T-lymphocyte responses to serotype-cross-reactive epitopes on nonstructural proteins following natural secondary dengue virus infection. J Virol 72 (1998) 3999
76. Zivny J., DeFronzo M., Jarry W., Jameson J., Cruz J., Ennis F.A., and Rothman A.R. Partial agonist effect influences the CTL response to a heterologous dengue virus serotype 1. J Immunol 163 (1999) 2754
77. Rothman A.R. Dengue: defining protective versus pathologic immunity. J Clin Invest 113 (2004) 946
78. Mongkolsapaya J., Dejnirattisai W., Xu X.N., Vasanawathana S., Tangthawornchaikul N., Chairunsri A., Sawasdivorn S., Duangchinda T., Dong T., Rowland-Jones S., Yenchitsomanus P.T., McMichael A., Malasit P., and Screaton G. Original antigenic sin and apoptosis in the patogénesis of dengue hemorrhagic fever. Nat Med 9 (2003) 921
79. Rodriguez-Roche R., Alvarez M., Gritsun T., Halstead S., Kouri G., Gould E.A., et al. Virus evolution during a severe dengue epidemic in Cuba, 1997. Virology 334 (2005) 154
80. Hill A.B., Mullbacher A., Parrish C., Coia G., Westaway E.G., and Blanden R.V. Broad cross-reactivity with marked fine-specificity in the cytotoxic T cell response to flaviviruses. J Gen Virol 73 (1992) 1115
81. Okamoto Y., Kurane I., Leporati A.M., and Ennis F.A. Definition of the region on NS3 which contains multiple epitopes recognised by dengue virus serotype-cross-reactive and flavivirus-cross-reactive, HLA-DPw2-restricted CD4+ T cell clones. J Gen Virol 79 (1998) 697
82. Matusan A.E., Pryor M.J., Davidson A.D., and Wright P.J. Mutagenesis of the Dengue virus type 2 NS3 protein within and outside helicase motifs: effects on enzyme activity and virus replication. J Virol 75 (2001) 9633
83. Simmons C.P., Dong T., Nguyen V.C., Nguyen Dung N.T.P., Chau T.N.B., Thao L.T.T., Nguyen T.D., Hien T.T., Rowland-Jones S., and Farrar J. Early T-cell responses to dengue virus epitopes in Vietnamese adults with secondary dengue virus infections. J Virol 79 (2005) 5665