Radiation-induced oxidative damage to the DNA-binding domain of the lactose repressor

Biochemical Journal

Volumn 403, Issue 3, 2007, Pages 463-472

  Gillard, Nathalie ^a   Goffinont, Stephane ^a   Buré, Corinne ^a   Davidkova, Marie ^b   Maurizot, Jean Claude ^a   Cadene, Martine ^a   Spotheim Maurizot, Melanie ^a  

^a CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^b NUCLEAR PHYSICS INSTITUTE   (Czech Republic)

Author keywords

Ionizing radiation; Lactose repressor; Mass spectrometry; Monte Carlo simulation; Protein oxidation; Radiolytic attack

Indexed keywords

COMPUTER SIMULATION; DNA; IONIZING RADIATION; MASS SPECTROMETRY; MONTE CARLO METHODS; OXIDATION; PROTEINS; RADIATION EFFECTS; RADIOLYSIS;

LACTOSE REPRESSOR; PROTEIN OXIDATION; RADIOLYTIC ATTACK;

GLUCOSE;

AMINO ACID; LACTOSE; METHIONINE; PROTEINASE; RADICAL; TYROSINE; BACTERIAL PROTEIN; CESIUM; DNA BINDING PROTEIN; HYDROXYL RADICAL; LACI PROTEIN, BACTERIA; REPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; DNA BINDING; DNA SEQUENCE; ELECTROSPRAY; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; GAMMA RADIATION; GENE EXPRESSION; GENETIC REGULATION; ION TRAP MASS SPECTROMETRY; IONIZING RADIATION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MONTE CARLO METHOD; NONHUMAN; OPERON; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECONDARY STRUCTURE; RADIATION; RADIOLYSIS; AMINO ACID SEQUENCE; ELECTROSPRAY MASS SPECTROMETRY; MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; PROTEIN DENATURATION; PROTEIN RENATURATION; RADIATION EXPOSURE; SPECTROFLUOROMETRY; TANDEM MASS SPECTROMETRY;

ESCHERICHIA COLI;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CESIUM RADIOISOTOPES; CIRCULAR DICHROISM; DNA-BINDING PROTEINS; HYDROXYL RADICAL; METHIONINE; OXIDATION-REDUCTION; PROTEIN DENATURATION; PROTEIN RENATURATION; PROTEIN STRUCTURE, SECONDARY; REPRESSOR PROTEINS; SPECTROMETRY, FLUORESCENCE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; TYROSINE;

EID: 34247891569     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20061466     Document Type: Article

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