A microsphere-based assay for multiplexed single nucleotide polymorphism analysis using single base chain extension

Genome Research

Volumn 10, Issue 4, 2000, Pages 549-557

  Chen, Jingwen ^a   Iannone, Marie A ^a   Li, May Sung ^a   Taylor, J David ^a   Rivers, Philip ^a   Nelsen, Anita J ^a   Slentz Kesler, Kimberly A ^a   Roses, Allen ^a   Weiner, Michael P ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOTIDE; DNA; DNA POLYMERASE; FLUORESCEIN; GENE PRODUCT; MICROSPHERE; OLIGONUCLEOTIDE;

ACCURACY; ANALYTIC METHOD; ARTICLE; ASSAY; CONTROLLED STUDY; DNA HYBRIDIZATION; DNA SEQUENCE; FLOW CYTOMETRY; GENETIC ANALYSIS; GENETIC CODE; GENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; VALIDATION PROCESS;

DNA, COMPLEMENTARY; FLOW CYTOMETRY; FLUORESCENT DYES; HUMANS; MICROSPHERES; POLYMORPHISM, SINGLE NUCLEOTIDE; SEQUENCE ANALYSIS, DNA;

EID: 0034060781     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.10.4.549     Document Type: Article

References (24)

1. Chen, X.N., B. Zehnbauer, A. Gnirke, and P.Y. Kwok. 1997. Fluorescence energy transfer detection as a homogeneous DNA diagnostic method. Proc. Natl. Acad. Sci. 94: 10756-10761.
2. Chen, X.N., L. Levine, and P.Y. Kwok. 1999. Fluorescence polarization in homogeneous nucleic acid analysis. Genome Res. 9: 492-498.
3. Cooper, D.N., B.A. Smith, H.J. Cooke, S. Niemann, and J. Schmidtke. 1985. An estimate of unique DNA sequence heterozygosity in the human genome. Hum. Genet. 69: 201-205.
4. Fu, D.J., K. Tang, A. Braun, D. Reuter, B. Darnhofer-Demar, D.P. Little, M.J. O'Donnell, C.R. Cantor, and H. Roster. 1998. Sequencing exons 5 to 8 of the p53 gene by MALDI-TOF mass spectrometry. Nat. Biotechnol. 16: 381-384.
5. Fulton, R.J., R.L. McDade, P.L. Smith, L.J. Kienker, and J.R. Kettman, J.. 1997. Advanced multiplexed analysis with the FlowMetrix system. Clin. Chem. 43: 1749-1756.
6. Gilles, P.N., D.J. Wu, C.B. Foster, P.J. Dillon, and S.J. Chanock. 1999. Single nucleotide polymorphic discrimination by an electronic dot blot assay on semiconductor microchips. Nat. Biotechnol. 17: 365-370.
7. Iannone, M.A., J.D. Taylor, J.W. Chen, M.S. Li, P. Rivers, K.A. Slentz-Kesler, and M.P. Weiner. 2000. Multiplexed single nucleotide polymorphism genotyping by oligonucleotide ligation and flow cytometry. Cytometry 39: 131-140.
8. Kettman, J.R., T. Davis, D. Chandler, K.G. Oliver, and R.J. Fulton. 1998. Classification and properties of 64 multiplexed microsphere sets. Cytometry 33: 234-243.
9. Lai, E., J. Riley, I. Purvis, and A. Roses. 1998. A 4-MB high-density single nucleotide polymorphism-based map around human APOE. Genomics 54: 31-38.
10. Landegren, U., R. Kaiser, J. Sanders, and L. Hood. 1988. A ligase-mediated gene detection technique. Science 241: 1077-1080.
11. Livak, K.J., J. Marmaro, and J.A. Todd. 1995. Towards fully automated genome-wide polymorphism screening. Nat. Genet. 9: 341-342.
12. Marshall, E. 1999. Drug firms to create public database of genetic mutations. Science 284: 406-467.
13. McDade, R.L. and R.L. Fulton. 1997. True multiplexed analysis by computer-enhanced flow cytometry. Med. Dev. Diag. Indust. 19(4): 75-82.
14. McHugh, T.M. 1994. Flow microsphere immunoassay for the quantitative and simultaneous detection of multiple soluble analytes. Methods Cell Biol. 42: 575-595.
15. Nikiforov, T.T., R.B. Rendle, P. Goelet, Y.H. Rogers, M.E. Kotewicz, S. Anderson, G.E. Trainor, and M.R. Knapp. 1994. Genetic bit analysis: A solid phase method for typing single nucleotide polymorphisms. Nucleic Acids Res. 22: 4167-4175.
16. Orita, M., H. Iwahana, H. Kanazawa, K. Hayashi, and T. Sekiya. 1989. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Natl. Acad. Sci. 86: 2766-2770.
17. Saiki, R.K., P.S. Walsh, C.H. Levenson, and H.A. Erlich. 1989. Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes. Proc. Natl. Acad. Sci. 86: 6230-6234.
18. Saunders, A.M., W.J. Strittmatter, D. Schmechel, P.H. George-Hyslop, M.A. Pericak-Vance, S.H. Joo, B.L. Rosi, J.F. Gusella, D.R. Crapper-MacLachlan, M.J. Alberts et al. 1993. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 43: 1467-1472.
19. Sheffield, V.C., D.Y. Nishimura, and E.M. Stone. 1995. Novel approaches to linkage mapping. Curr. Opin. Genet. Dev. 5: 335-341.
20. Shoemaker, D.D., D.A. Lashkari, D. Morris, M. Mittmann, and R.W. Davis. 1996. Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy. Nat. Genet. 14: 450-456.
21. Strittmatter, W.J., A.M. Saunders, D. Schmechel, M. Pericak-Vance, J. Enghild, G.S. Salvesen, and A.D. Roses. 1993. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc. Natl. Acad. Sci. 90: 1977-1981.
22. Syvanen, A.C. 1999. From gels to chips: "Minisequencing" primer extension for analysis of point mutations and single nucleotide polymorphisms. Hum. Mutat. 13: 1-10.
23. Syvanen, A.C., K. Aalto-Setala, E. Harju, K. Kontula, and H. Soderlund. 1990. A primer-guided nucleotide incorporation assay in the genotyping of apolipoprotein E. Genomics 8: 684-692.
24. Tyagi, S., D.P. Bratu, and F.R. Kramer. 1998. Multicolor molecular beacons for allele discrimination. Nat. Biotechnol. 16: 49-53.