메뉴 건너뛰기




Volumn 26, Issue 20, 2007, Pages 2945-2949

Ikaros is a mutational target for lymphomagenesis in Mlh1-deficient mice

Author keywords

Coding microsatellites; DNA mismatch repair; Microsatellite instability; Mutational target gene; T cell lymphoma

Indexed keywords

IKAROS TRANSCRIPTION FACTOR; PROTEIN MLH1;

EID: 34247877677     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210100     Document Type: Article
Times cited : (11)

References (33)
  • 1
  • 2
    • 0035253196 scopus 로고    scopus 로고
    • Elevated mutant frequencies and increased C: G → T: A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells
    • Baross-Francis A, Makhani N, Liskay RM, Jirik FR. (2001). Elevated mutant frequencies and increased C: G → T: A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells. Oncogene 20: 619-625.
    • (2001) Oncogene , vol.20 , pp. 619-625
    • Baross-Francis, A.1    Makhani, N.2    Liskay, R.M.3    Jirik, F.R.4
  • 3
    • 0028221943 scopus 로고
    • Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer
    • Bronner CE, Baker SM, Morrison PT, Warren G, Smith LG, Lescoe MK et al. (1994). Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer. Nature 368: 258-261.
    • (1994) Nature , vol.368 , pp. 258-261
    • Bronner, C.E.1    Baker, S.M.2    Morrison, P.T.3    Warren, G.4    Smith, L.G.5    Lescoe, M.K.6
  • 4
    • 0034518673 scopus 로고    scopus 로고
    • Candidate mutator genes in mismatch repair-deficient thymic lymphomas: No evidence of mutations in the DNA polymerase delta gene
    • Campbell MR, Thang TY, Jirik FR, Andrew SE. (2000). Candidate mutator genes in mismatch repair-deficient thymic lymphomas: no evidence of mutations in the DNA polymerase delta gene. Carcinogenesis 21: 2281-2285.
    • (2000) Carcinogenesis , vol.21 , pp. 2281-2285
    • Campbell, M.R.1    Thang, T.Y.2    Jirik, F.R.3    Andrew, S.E.4
  • 6
    • 0036569940 scopus 로고    scopus 로고
    • Mutations at coding repeat sequences in mismatch repair-deficient human cancers: Toward a new concept of target genes for instability
    • Duval A, Hamelin R. (2002). Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 62: 2447-2454.
    • (2002) Cancer Res , vol.62 , pp. 2447-2454
    • Duval, A.1    Hamelin, R.2
  • 7
    • 0027742295 scopus 로고
    • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer
    • Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J et al. (1993). The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell 75: 1027-1038.
    • (1993) Cell , vol.75 , pp. 1027-1038
    • Fishel, R.1    Lescoe, M.K.2    Rao, M.R.3    Copeland, N.G.4    Jenkins, N.A.5    Garber, J.6
  • 8
    • 0026451087 scopus 로고
    • Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment
    • Georgopoulos K, Moore DD, Derfler B. (1992). Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment. Science 258: 808-812.
    • (1992) Science , vol.258 , pp. 808-812
    • Georgopoulos, K.1    Moore, D.D.2    Derfler, B.3
  • 9
    • 0037158899 scopus 로고    scopus 로고
    • Mismatch repair deficiency in hematological malignancies with microsatellite instability
    • Gu L, Cline-Brown B, Zhang F, Qiu L, Li GM. (2002). Mismatch repair deficiency in hematological malignancies with microsatellite instability. Oncogene 21: 5758-5764.
    • (2002) Oncogene , vol.21 , pp. 5758-5764
    • Gu, L.1    Cline-Brown, B.2    Zhang, F.3    Qiu, L.4    Li, G.M.5
  • 11
    • 15544384575 scopus 로고    scopus 로고
    • Frequent retention of heterozygosity for point mutations in p53 and Ikaros in N-ethyl-N-nitrosourea-induced mouse thymic lymphomas
    • Kakinuma S, Nishimura M, Kubo A, Nagai JY, Amasaki Y, Majima HJ et al. (2005). Frequent retention of heterozygosity for point mutations in p53 and Ikaros in N-ethyl-N-nitrosourea-induced mouse thymic lymphomas. Mutat Res 572: 132-141.
    • (2005) Mutat Res , vol.572 , pp. 132-141
    • Kakinuma, S.1    Nishimura, M.2    Kubo, A.3    Nagai, J.Y.4    Amasaki, Y.5    Majima, H.J.6
  • 12
    • 0036204339 scopus 로고    scopus 로고
    • Spectrum of Znfn1a1 (Ikaros) inactivation and its association with loss of heterozygosity in radiogenic T-cell lymphomas in susceptible B6C3F1 mice
    • Kakinuma S, Nishimura M, Sasanuma S, Mita K, Suzuki G, Katsura Y et al. (2002). Spectrum of Znfn1a1 (Ikaros) inactivation and its association with loss of heterozygosity in radiogenic T-cell lymphomas in susceptible B6C3F1 mice. Radiat Res 157: 331-340.
    • (2002) Radiat Res , vol.157 , pp. 331-340
    • Kakinuma, S.1    Nishimura, M.2    Sasanuma, S.3    Mita, K.4    Suzuki, G.5    Katsura, Y.6
  • 13
    • 0036569633 scopus 로고    scopus 로고
    • Point mutations and deletions in the znfn1a1/ikaros gene in chemically induced murine lymphomas
    • Karlsson A, Soderkvist P, Zhuang SM. (2002). Point mutations and deletions in the znfn1a1/ikaros gene in chemically induced murine lymphomas. Cancer Res 62: 2650-2653.
    • (2002) Cancer Res , vol.62 , pp. 2650-2653
    • Karlsson, A.1    Soderkvist, P.2    Zhuang, S.M.3
  • 14
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach FS, Nicolaides NC, Papadopoulos N, Liu B, Jen J, Parsons R et al. (1993). Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 75: 1215-1225.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papadopoulos, N.3    Liu, B.4    Jen, J.5    Parsons, R.6
  • 15
    • 0034161461 scopus 로고    scopus 로고
    • MSH2-deficient murine lymphomas harbor insertion/deletion mutations in the transforming growth factor beta receptor type 2 gene and display low not high frequency microsatellite instability
    • Lowsky R, Magliocco A, Ichinohasama R, Reitmair A, Scott S, Henry M et al. (2000). MSH2-deficient murine lymphomas harbor insertion/deletion mutations in the transforming growth factor beta receptor type 2 gene and display low not high frequency microsatellite instability. Blood 95: 1767-1772.
    • (2000) Blood , vol.95 , pp. 1767-1772
    • Lowsky, R.1    Magliocco, A.2    Ichinohasama, R.3    Reitmair, A.4    Scott, S.5    Henry, M.6
  • 16
    • 0035015540 scopus 로고    scopus 로고
    • Microsatellite instability in acute myelocytic leukaemia developed from A-bomb survivors
    • Nakanishi M, Tanaka K, Takahashi T, Kyo T, Dohy H, Fujiwara M et al. (2001). Microsatellite instability in acute myelocytic leukaemia developed from A-bomb survivors. Int J Radiat Biol 77: 687-694.
    • (2001) Int J Radiat Biol , vol.77 , pp. 687-694
    • Nakanishi, M.1    Tanaka, K.2    Takahashi, T.3    Kyo, T.4    Dohy, H.5    Fujiwara, M.6
  • 17
    • 0033566987 scopus 로고    scopus 로고
    • Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia
    • Nakayama H, Ishimaru F, Avitahl N, Sezaki N, Fujii N, Nakase K et al. (1999). Decreases in Ikaros activity correlate with blast crisis in patients with chronic myelogenous leukemia. Cancer Res 59: 3931-3934.
    • (1999) Cancer Res , vol.59 , pp. 3931-3934
    • Nakayama, H.1    Ishimaru, F.2    Avitahl, N.3    Sezaki, N.4    Fujii, N.5    Nakase, K.6
  • 18
    • 0033581933 scopus 로고    scopus 로고
    • Homozygous deletions and point mutations of the Ikaros gene in gamma-ray-induced mouse thymic lymphomas
    • Okano H, Saito Y, Miyazawa T, Shinbo T, Chou D, Kosugi S et al. (1999). Homozygous deletions and point mutations of the Ikaros gene in gamma-ray-induced mouse thymic lymphomas. Oncogene 18: 6677-6683.
    • (1999) Oncogene , vol.18 , pp. 6677-6683
    • Okano, H.1    Saito, Y.2    Miyazawa, T.3    Shinbo, T.4    Chou, D.5    Kosugi, S.6
  • 20
    • 0038106526 scopus 로고    scopus 로고
    • Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor
    • Papathanasiou P, Perkins AC, Cobb BS, Ferrini R, Sridharan R, Hoyne GF et al. (2003). Widespread failure of hematolymphoid differentiation caused by a recessive niche-filling allele of the Ikaros transcription factor. Immunity 19: 131-144.
    • (2003) Immunity , vol.19 , pp. 131-144
    • Papathanasiou, P.1    Perkins, A.C.2    Cobb, B.S.3    Ferrini, R.4    Sridharan, R.5    Hoyne, G.F.6
  • 21
    • 0027137935 scopus 로고
    • Hypermutability and mismatch repair deficiency in RER + tumor cells
    • Parsons R, Li GM, Longley MJ, Fang WH, Papadopoulos N, Jen J et al. (1993). Hypermutability and mismatch repair deficiency in RER + tumor cells. Cell 75: 1227-1236.
    • (1993) Cell , vol.75 , pp. 1227-1236
    • Parsons, R.1    Li, G.M.2    Longley, M.J.3    Fang, W.H.4    Papadopoulos, N.5    Jen, J.6
  • 23
    • 0345222475 scopus 로고    scopus 로고
    • Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1
    • Ricciardone MD, Ozcelik T, Cevher B, Ozdag H, Tuncer M, Gurgey A et al. (1999). Human MLH1 deficiency predisposes to hematological malignancy and neurofibromatosis type 1. Cancer Res 59: 290-293.
    • (1999) Cancer Res , vol.59 , pp. 290-293
    • Ricciardone, M.D.1    Ozcelik, T.2    Cevher, B.3    Ozdag, H.4    Tuncer, M.5    Gurgey, A.6
  • 24
    • 0141789641 scopus 로고    scopus 로고
    • Genetic susceptibility to thymic lymphomas and K-ras gene mutation in mice after exposure to X-rays and N-ethyl-N-nitrosourea
    • Shimada Y, Nishimura M, Kakinuma S, Ogiu T, Fujimoto H, Kubo A et al. (2003). Genetic susceptibility to thymic lymphomas and K-ras gene mutation in mice after exposure to X-rays and N-ethyl-N-nitrosourea. Int J Radiat Biol 79: 423-430.
    • (2003) Int J Radiat Biol , vol.79 , pp. 423-430
    • Shimada, Y.1    Nishimura, M.2    Kakinuma, S.3    Ogiu, T.4    Fujimoto, H.5    Kubo, A.6
  • 25
    • 0033817818 scopus 로고    scopus 로고
    • Radiation-associated loss of heterozygosity at the Znfn1a1 (Ikaros) locus on chromosome 11 in murine thymic lymphomas
    • Shimada Y, Nishimura M, Kakinuma S, Okumoto M, Shiroishi T, Clifton KH et al. (2000). Radiation-associated loss of heterozygosity at the Znfn1a1 (Ikaros) locus on chromosome 11 in murine thymic lymphomas. Radiat Res 154: 293-300.
    • (2000) Radiat Res , vol.154 , pp. 293-300
    • Shimada, Y.1    Nishimura, M.2    Kakinuma, S.3    Okumoto, M.4    Shiroishi, T.5    Clifton, K.H.6
  • 26
    • 6544243426 scopus 로고    scopus 로고
    • Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemia
    • Sun L, Crotty ML, Sensel M, Sather H, Navara C, Nachman J et al. (1999a). Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemia. Clin Cancer Res 5: 2112-2120.
    • (1999) Clin Cancer Res , vol.5 , pp. 2112-2120
    • Sun, L.1    Crotty, M.L.2    Sensel, M.3    Sather, H.4    Navara, C.5    Nachman, J.6
  • 27
    • 0033582324 scopus 로고    scopus 로고
    • Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia
    • Sun L, Heerema N, Crotty L, Wu X, Navara C, Vassilev A et al. (1999b). Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia. Proc Natl Acad Sci USA 96: 680-685.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 680-685
    • Sun, L.1    Heerema, N.2    Crotty, L.3    Wu, X.4    Navara, C.5    Vassilev, A.6
  • 28
    • 33645350398 scopus 로고    scopus 로고
    • Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: Evaluation of the late effect of radiation on a mouse model of HNPCC
    • Tokairin Y, Kakinuma S, Arai M, Nishimura M, Okamoto M, Ito E et al. (2006). Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC. Int J Exp Pathol 87: 89-99.
    • (2006) Int J Exp Pathol , vol.87 , pp. 89-99
    • Tokairin, Y.1    Kakinuma, S.2    Arai, M.3    Nishimura, M.4    Okamoto, M.5    Ito, E.6
  • 29
    • 0030498975 scopus 로고    scopus 로고
    • Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation
    • Wang JH, Nichogiannopoulou A, Wu L, Sun L, Sharpe AH, Bigby M et al. (1996). Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5: 537-549.
    • (1996) Immunity , vol.5 , pp. 537-549
    • Wang, J.H.1    Nichogiannopoulou, A.2    Wu, L.3    Sun, L.4    Sharpe, A.H.5    Bigby, M.6
  • 31
    • 0028866897 scopus 로고
    • A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma
    • Winandy S, Wu P, Georgopoulos K. (1995). A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Cell 83: 289-299.
    • (1995) Cell , vol.83 , pp. 289-299
    • Winandy, S.1    Wu, P.2    Georgopoulos, K.3
  • 32
    • 20944440949 scopus 로고    scopus 로고
    • Microsatellite instability of selective target genes in HNPCC-associated colon adenomas
    • Woerner SM, Kloor M, Mueller A, Rueschoff J, Friedrichs N, Buettner R et al. (2005). Microsatellite instability of selective target genes in HNPCC-associated colon adenomas. Oncogene 24: 2525-2535.
    • (2005) Oncogene , vol.24 , pp. 2525-2535
    • Woerner, S.M.1    Kloor, M.2    Mueller, A.3    Rueschoff, J.4    Friedrichs, N.5    Buettner, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.