메뉴 건너뛰기




Volumn 101, Issue 2, 2007, Pages 517-528

Proliferation of human breast cancer cells and anti-cancer action of doxorubicin and vinblastine are independent of PKC-α

Author keywords

Cytotoxicity; Doxorubicin; MCF 7 breast cell; Proliferation; Protein kinase C; Vinblastine

Indexed keywords

DOXORUBICIN; PHORBOL DIBUTYRATE; PHORBOL ESTER; PROTEIN KINASE C ALPHA; PROTEIN KINASE C INHIBITOR; STAUROSPORINE; VINBLASTINE;

EID: 34247874518     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.21202     Document Type: Article
Times cited : (7)

References (35)
  • 1
    • 0028670129 scopus 로고
    • Regulation of protein kinase C and role in cancer biology
    • Blobe GC, Obeid LM, Hannun YA. 1994. Regulation of protein kinase C and role in cancer biology. Cancer Metastasis Rev 13:411-431.
    • (1994) Cancer Metastasis Rev , vol.13 , pp. 411-431
    • Blobe, G.C.1    Obeid, L.M.2    Hannun, Y.A.3
  • 2
    • 0042697468 scopus 로고    scopus 로고
    • The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide
    • Brantley-Finley C, Lyle CS, Du L, Goodwin ME, Hall T, Szwedo D, Kaushal GP, Chambers TC. 2003. The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochem Pharmacol 66:459-469.
    • (2003) Biochem Pharmacol , vol.66 , pp. 459-469
    • Brantley-Finley, C.1    Lyle, C.S.2    Du, L.3    Goodwin, M.E.4    Hall, T.5    Szwedo, D.6    Kaushal, G.P.7    Chambers, T.C.8
  • 3
    • 0027104825 scopus 로고
    • The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation
    • Clemens MJ, Trayner I, Menaya J. 1992. The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation. J Cell Sci 103:881-887.
    • (1992) J Cell Sci , vol.103 , pp. 881-887
    • Clemens, M.J.1    Trayner, I.2    Menaya, J.3
  • 6
    • 0032486223 scopus 로고    scopus 로고
    • Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-α
    • Dennis JU, Dean NM, Bennett CF, Griffith JW, Lang CM, Welch DR. 1998. Human melanoma metastasis is inhibited following ex vivo treatment with an antisense oligonucleotide to protein kinase C-α. Cancer Lett 128: 65-70.
    • (1998) Cancer Lett , vol.128 , pp. 65-70
    • Dennis, J.U.1    Dean, N.M.2    Bennett, C.F.3    Griffith, J.W.4    Lang, C.M.5    Welch, D.R.6
  • 7
    • 0028833510 scopus 로고
    • Protein kinase C (PKC)-induced PKC down-regulation
    • Goode NT, Hajibagheri MAN, Parker PJ. 1995. Protein kinase C (PKC)-induced PKC down-regulation. J Biol Chem 270:2669-2673.
    • (1995) J Biol Chem , vol.270 , pp. 2669-2673
    • Goode, N.T.1    Hajibagheri, M.A.N.2    Parker, P.J.3
  • 8
    • 0027322679 scopus 로고    scopus 로고
    • Protein kinase C isoenzymes: Divergence in signal transduction?
    • Hug H, Sarre TF. 2005. Protein kinase C isoenzymes: divergence in signal transduction? Biochem J 291:329-343.
    • (2005) Biochem J , vol.291 , pp. 329-343
    • Hug, H.1    Sarre, T.F.2
  • 9
    • 0141682436 scopus 로고    scopus 로고
    • Inhibition of protein kinase Cα enhances anticancer agent-induced loss of anchorage-independent growth regardless of protection against apoptosis by Bcl-2
    • Huigsloot M, Tijdens RB, van de Water B. 2003. Inhibition of protein kinase Cα enhances anticancer agent-induced loss of anchorage-independent growth regardless of protection against apoptosis by Bcl-2. Mol Pharmacol 64:965-973.
    • (2003) Mol Pharmacol , vol.64 , pp. 965-973
    • Huigsloot, M.1    Tijdens, R.B.2    van de Water, B.3
  • 11
    • 0025824979 scopus 로고
    • Mechanism of inhibition of cell proliferation by Vinca alkaloids
    • Jordan MA, Thrower D, Wilson L. 1991. Mechanism of inhibition of cell proliferation by Vinca alkaloids. Cancer Res 51:2212-2222.
    • (1991) Cancer Res , vol.51 , pp. 2212-2222
    • Jordan, M.A.1    Thrower, D.2    Wilson, L.3
  • 12
    • 0026602830 scopus 로고
    • Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines
    • Kennedy MJ, Prestigiacomo LJ, Tyler G, May WS, Davidson NE. 1992. Differential effects of bryostatin 1 and phorbol ester on human breast cancer cell lines. Cancer Res 52:1278-1283.
    • (1992) Cancer Res , vol.52 , pp. 1278-1283
    • Kennedy, M.J.1    Prestigiacomo, L.J.2    Tyler, G.3    May, W.S.4    Davidson, N.E.5
  • 13
    • 0027255130 scopus 로고
    • Activation and substrate specificity of the human protein kinase C α and zeta isoenzymes
    • Kochs G, Hummel R, Meyer D, Hug H, Marme D, Sarre TF. 1993. Activation and substrate specificity of the human protein kinase C α and zeta isoenzymes. Eur J Biochem 216:597-606.
    • (1993) Eur J Biochem , vol.216 , pp. 597-606
    • Kochs, G.1    Hummel, R.2    Meyer, D.3    Hug, H.4    Marme, D.5    Sarre, T.F.6
  • 14
    • 0030865271 scopus 로고    scopus 로고
    • Activation of protein kinase C-a isoform in murine melanoma cells with high metastatic potential
    • La Porta CAM, Comolli R. 1997. Activation of protein kinase C-a isoform in murine melanoma cells with high metastatic potential. Clin Exp Metastasis 15:568-579.
    • (1997) Clin Exp Metastasis , vol.15 , pp. 568-579
    • La Porta, C.A.M.1    Comolli, R.2
  • 15
    • 0032514916 scopus 로고    scopus 로고
    • Evidence of z protein kinase C Involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis
    • Laudanna C, Mochly-Rosen D, Liron T, Constantin G, Butcher EC. 1998. Evidence of z protein kinase C Involvement in polymorphonuclear neutrophil integrin-dependent adhesion and chemotaxis. J Biol Chem 273: 30306-30315.
    • (1998) J Biol Chem , vol.273 , pp. 30306-30315
    • Laudanna, C.1    Mochly-Rosen, D.2    Liron, T.3    Constantin, G.4    Butcher, E.C.5
  • 16
    • 33750895245 scopus 로고    scopus 로고
    • 2 isoforms by TNF-α and IL-1β in adult rat ventricular myocytes
    • 2 isoforms by TNF-α and IL-1β in adult rat ventricular myocytes. Am J Physiol 44:H1462-H1472.
    • (1998) Am J Physiol , vol.44
    • Liu, S.J.1    McHowat, J.2
  • 19
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: Molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G, Menna P, Salvatorelli E, Cairo G, Gianni L. 2004. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol Rev 56:185-229.
    • (2004) Pharmacol Rev , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 20
    • 0029060391 scopus 로고
    • Protein kinase C and lipid signaling for sustained cellular responses
    • Nishizuka Y. 1995. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J 9:484-496.
    • (1995) FASEB J , vol.9 , pp. 484-496
    • Nishizuka, Y.1
  • 21
    • 0035695214 scopus 로고    scopus 로고
    • Prospects for targeting protein kinase C isozymes in the therapy of drug-resistant cancer-An evolving story
    • O'Brian CA, Ward NE, Stewart JR, Chu F. 2001. Prospects for targeting protein kinase C isozymes in the therapy of drug-resistant cancer-An evolving story. Cancer Metastasis Rev 20:95-100.
    • (2001) Cancer Metastasis Rev , vol.20 , pp. 95-100
    • O'Brian, C.A.1    Ward, N.E.2    Stewart, J.R.3    Chu, F.4
  • 22
  • 23
    • 0027093254 scopus 로고
    • Staurosporine-induced neurite outgrowth in PC12 cells is independent of protein kinase C inhibition
    • Rasouly D, Rahamim E, Lester D, Matsuda Y, Lazarovici P. 1992. Staurosporine-induced neurite outgrowth in PC12 cells is independent of protein kinase C inhibition. Mol Pharmacol 42:35-43.
    • (1992) Mol Pharmacol , vol.42 , pp. 35-43
    • Rasouly, D.1    Rahamim, E.2    Lester, D.3    Matsuda, Y.4    Lazarovici, P.5
  • 24
    • 0032554628 scopus 로고    scopus 로고
    • Cross-talk between protein kinase C-α (PKC-α) and -δ (PKC-δ): PKC-a elevates the PKC-d protein level, altering its mRNA transcription and degradation
    • Romanova LY, Alexandrov IA, Nordan RP, Blagosklonny MV, Mushinski JF. 1998. Cross-talk between protein kinase C-α (PKC-α) and -δ (PKC-δ): PKC-a elevates the PKC-d protein level, altering its mRNA transcription and degradation. Biochemistry 37:5558-5565.
    • (1998) Biochemistry , vol.37 , pp. 5558-5565
    • Romanova, L.Y.1    Alexandrov, I.A.2    Nordan, R.P.3    Blagosklonny, M.V.4    Mushinski, J.F.5
  • 25
    • 2342626503 scopus 로고    scopus 로고
    • Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay
    • Saraiva L, Fresco P, Pinto E, Goncalves J. 2004. Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay. Eur J Pharmacol 491:101-110.
    • (2004) Eur J Pharmacol , vol.491 , pp. 101-110
    • Saraiva, L.1    Fresco, P.2    Pinto, E.3    Goncalves, J.4
  • 26
    • 0033050632 scopus 로고    scopus 로고
    • Overexpression of protein kinase ca in MCF-10A human breast cells engenders dramatic alterations in morphology, proliferation, and motility
    • Sun Xg, Rotenberg SA. 1999. Overexpression of protein kinase ca in MCF-10A human breast cells engenders dramatic alterations in morphology, proliferation, and motility. Cell Growth Differ 10:343-352.
    • (1999) Cell Growth Differ , vol.10 , pp. 343-352
    • Sun, X.1    Rotenberg, S.A.2
  • 27
    • 0141594871 scopus 로고    scopus 로고
    • Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the akt survival pathway
    • Tanaka Y, Gavrielides MV, Mitsuuchi Y, Fujii T, Kazanietz MG. 2003. Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the akt survival pathway. J Biol Chem 278:33753-33762.
    • (2003) J Biol Chem , vol.278 , pp. 33753-33762
    • Tanaka, Y.1    Gavrielides, M.V.2    Mitsuuchi, Y.3    Fujii, T.4    Kazanietz, M.G.5
  • 29
    • 0033542806 scopus 로고    scopus 로고
    • Antisense inhibition of protein kinase ca reverses the transformed phenotype in human lung carcinoma cells
    • Wang XY, Repasky E, Liu HT. 1999. Antisense inhibition of protein kinase ca reverses the transformed phenotype in human lung carcinoma cells. Exper Cell Res 250:253-263.
    • (1999) Exper Cell Res , vol.250 , pp. 253-263
    • Wang, X.Y.1    Repasky, E.2    Liu, H.T.3
  • 31
    • 0028903545 scopus 로고
    • MCF-7 breast cancer cells transfected with protein kinase C-α exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype
    • Ways DK, Kukoly CA, deVente J, Hooker JL, Bryant WO, Posekany KJ, Fletcher DJ, Cook PP, Parker PJ. 1995. MCF-7 breast cancer cells transfected with protein kinase C-α exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype. J Clin Invest 95:1906-1915.
    • (1995) J Clin Invest , vol.95 , pp. 1906-1915
    • Ways, D.K.1    Kukoly, C.A.2    deVente, J.3    Hooker, J.L.4    Bryant, W.O.5    Posekany, K.J.6    Fletcher, D.J.7    Cook, P.P.8    Parker, P.J.9
  • 32
    • 21244468567 scopus 로고    scopus 로고
    • Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2
    • Wen-Sheng W, Jun-Ming H. 2005. Activation of protein kinase C alpha is required for TPA-triggered ERK (MAPK) signaling and growth inhibition of human hepatoma cell HepG2. J Biomed Sci 12:289-296.
    • (2005) J Biomed Sci , vol.12 , pp. 289-296
    • Wen-Sheng, W.1    Jun-Ming, H.2
  • 33
    • 0032537024 scopus 로고    scopus 로고
    • Loss of protein kinase C function induces an apoptotic response
    • Whelan RDH, Parker PJ. 1998. Loss of protein kinase C function induces an apoptotic response. Oncogene 16: 1939-1944.
    • (1998) Oncogene , vol.16 , pp. 1939-1944
    • Whelan, R.D.H.1    Parker, P.J.2
  • 34
    • 0035653457 scopus 로고    scopus 로고
    • Reduced expression of Wnt-1 and E-cadherin, and diminished beta-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-α
    • Williams CL, Noti JD. 2001. Reduced expression of Wnt-1 and E-cadherin, and diminished beta-catenin stability in MCF-7 breast cancer cells that overexpress protein kinase C-α. Intl J Oncology 19:1227-1233.
    • (2001) Intl J Oncology , vol.19 , pp. 1227-1233
    • Williams, C.L.1    Noti, J.D.2
  • 35
    • 0023655187 scopus 로고
    • Downregulation of protein kinase C is due to an increased rate of degradation
    • Young S, Parker PJ, Ullrich A, Stabel S. 1987. Downregulation of protein kinase C is due to an increased rate of degradation. Biochem J 244:775-779.
    • (1987) Biochem J , vol.244 , pp. 775-779
    • Young, S.1    Parker, P.J.2    Ullrich, A.3    Stabel, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.