Genetic and environmental influences on the development of alcoholism: Resilience vs. risk

Annals of the New York Academy of Sciences

Volumn 1094, Issue , 2006, Pages 193-201

  Enoch, Mary Anne ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Adolescents; COMT; HTTLPR; MAOA; Polymorphism

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; CATECHOL METHYLTRANSFERASE; SEROTONIN TRANSPORTER;

ADOLESCENCE; ADULTHOOD; ALCOHOL CONSUMPTION; ALCOHOLISM; ANTISOCIAL BEHAVIOR; CONFERENCE PAPER; DEPRESSION; ENVIRONMENTAL FACTOR; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HERITABILITY; HIGH RISK BEHAVIOR; HUMAN; NONHUMAN; PARENTAL ATTITUDE; PEER GROUP; PREGNANCY; PREVALENCE; RISK ASSESSMENT; SEDATION; STRESS; ADAPTIVE BEHAVIOR; ADOLESCENT; CHILD; ENVIRONMENT; FEMALE; GENETICS; MALE; PSYCHOLOGICAL ASPECT; REVIEW; RISK FACTOR;

PRIMATES;

ADAPTATION, PSYCHOLOGICAL; ADOLESCENT; ALCOHOLISM; CHILD; ENVIRONMENT; FEMALE; HUMANS; MALE; RISK FACTORS;

EID: 34247867965     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1376.019     Document Type: Conference Paper

References (41)

1. JOHNSTON, L.D., P.M. O'MALLEY, J.G. BACHMAN, et al. 2005. Monitoring the Future. National Results on Adolescent Drug Use: Overview of Key Findings, 2004. (NIH Publication No. 05-5726). National Institute on Drug Abuse. Bethesda, MD.
2. HARFORD, T.C., B.F. GRANT, H.Y. YI, et al. 2005. Patterns of DSM-IV alcohol abuse and dependence criteria among adolescents and adults: results from the 2001 National Household Survey on Drug Abuse. Alcohol. Clin. Exp. Res. 29: 810-828.
3. KESSLER, R.C., P. BERGLUND, O. DEMLER, et al. 2005. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch. Gen. Psychiatry 62: 593-602.
4. KOOB, G.F. 2003. Alcoholism: allostasis and beyond. Alcohol. Clin. Exp. Res. 27: 232-243.
5. GOLDMAN, D., G. OROSZI & F. DUCCI. 2005. The genetics of addictions: uncovering the genes. Nat. Rev. Genet. 6: 521-532.
6. ENOCH, M.-A. 2003. Pharmacogenomics of alcohol response and addiction. Am. J. PharmacoGenomics 3: 217-232.
7. ENOCH, M.-A. 2006. Genetics, stress and the risk for addiction. In Stress and Addiction: Biological and Psychological Mechanisms. M. al'Absi, Ed.: 127-146. Elsevier Neuroscience. New York. In Press.
8. BONOMO, Y.A., G. BOWES, C. COFFEY, et al. 2004. Teenage drinking and the onset of alcohol dependence: a cohort study over seven years. Addiction 99: 1520-1528.
9. GRANT, B.F. & D.A. DAWSON. 1998. Age of onset of drug use and its association with DSM-IV drug abuse and dependence: results from the National Longitudinal Alcohol Epidemiologic Survey. J. Subst. Abuse 10: 163-173.
10. DE BELLIS, M.D., D.B. CLARK & S.R. BEERS. 2000. Hippocampal volume in adolescent-onset alcohol use disorders. Am. J. Psychiatry 157: 737-744.
11. HILLER-STURMHOFEL, S. & H.S. SWARTZWELDER. 2004/2005. Alcohol's effects on the adolescent brain. Alcohol Res. Health 28: 213-221.
12. CREWS, F.T. & K. NIXON. 2005. Adolescent binge drinking causes life-long changes in brain. In Monti P.M., Miranda R. Jr., Nixon K. et al. Adolescence: booze, brains, and behavior. Alcohol. Clin. Exp. Res. 29: 207-220.
13. SCHUCKIT, M.A. 1994. Low level of response to alcohol as a predictor of future alcoholism. Am. J. Psychiatry 151: 184-189.
14. WILSNACK, S.C., N.D. VOGELTANZ, A.D. KLASSEN, et al. 1997. Childhood sexual abuse and women's substance abuse: national survey findings. J. Stud. Alcohol 58: 264-271.
15. NATIONAL INSTITUTE ON DRUG ABUSE (NIDA). 1994. Capsules, Women Drug Abuse 6: 2.
16. KOSS, M.P., N.P. YUAN, D. DIGHTMAN, et al. 2003. Adverse childhood exposures and alcohol dependence among seven Native American tribes. Am. J. Prev. Med. 25: 238-244.
17. KIM-COHEN, J., T.E. MOFFITT, A. TAYLOR, et al. 2005. Maternal depression and children's antisocial behavior: nature and nurture effects. Arch. Gen. Psychiatry 62: 173-181.
18. NIEMELA, S., A. SOURANDER, K. POIKOLAINEN, et al. 2006. Childhood predictors of drunkenness in late adolescence among males: a 10-year population-based follow-up study. Addiction 101: 512-521.
19. WEAVER, I.C., N. CERVONI, F.A. CHAMPAGNE, et al. 2004. Epigenetic programming by maternal behavior. Nat. Neurosci. 7: 847-854.
20. NEUMARK, Y.D., Y. FRIEDLANDER, R. DURST, et al. 2004. Alcohol dehydrogenase polymorphisms influence alcohol-elimination rates in a male Jewish population. Alcohol Clin. Exp. Res. 28: 10-14.
21. THOMASSON, H.R., H.J. EDENBURG, D.W. CRABB, et al 1991. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am. J. Hum. Genet. 48: 677-681.
22. NEUMARK, Y.D., Y. FRIEDLANDER, H.R. THOMASSON, et al. 1998. Association of the ADH2*2 allele with reduced ethanol consumption in Jewish men in Israel: a pilot study. J. Stud. Alcohol 59: 133-139.
23. MONTEIRO, M.G., J.L. KLEIN, M.A. SCHUCKIT. 1991. High levels of sensitivity to alcohol in young adult Jewish men: a pilot study. J. Stud. Alcohol 52: 464-469.
24. TIET, Q.Q., H.R. BIRD, M. DAVIES, et al. 1998. Adverse life events and resilience. J. Am. Acad. Child. Adolesc. Psychiatry 37: 1191-1200.
25. CASPI, A., J. MCCLAY, T.E. MOFFITT, et al. 2002. Role of genotype in the cycle of violence in maltreated children. Science 297: 851-853.
26. FOLEY, D.L., L.J. EAVES, B. WORMLEY, et al. 2004. Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder. Arch. Gen. Psychiatry 61: 738-744.
27. HARIRI, A.R., E.M. DRABANT, K.E. MUNOZ, et al. 2005. A susceptibility gene for affective disorders and the response of the human amygdala. Arch. Gen. Psychiatry 62: 146-152.
28. HEINZ, A., D.F. BRAUS, M.N. SMOLKA, et al. 2005. Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter. Nat. Neurosci. 8: 20-21.
29. DREVETS, W.C. 2003. Neuroimaging abnormalities in the amygdala in mood disorders. Ann. N. Y. Acad. Sci. 985: 420-444.
30. CASPI, A., K. SUGDEN, T.E. MOFFITT, et al. 2003. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301: 386-389.
31. KENDLER, K.S., J.W. KUHN, J. VITTUM, et al. 2005. The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication. Arch. Gen. Psychiatry 62: 529-535.
32. KAUFMAN, J., B.Z. YANG, H. DOUGLAS- PALUMBERI, et al. 2004. Social supports and serotonin transporter gene moderate depression in maltreated children. Proc. Natl. Acad. Sci. USA 101: 17316-17321.
33. BARR, C.S., T.K. NEWMAN, S. LINDELL, et al. 2004. Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates. Arch. Gen. Psychiatry 61: 1146-1152.
34. SMOLKA, M.N., G. SCHUMANN, J. WRASE, et al. 2005. Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex. J. Neurosci. 25: 836-842.
35. ENOCH, M.A., K. XU, E. FERRO, et al. 2003. Genetic origins of anxiety in women: a role for a functional catechol-O-methyltransferase polymorphism. Psychiatr. Genet. 13: 33-41.
36. OLSSON, C.A., R.J. ANNEY, M. LOTFI-M IRI, et al. 2005. Association between the COMT Val158Met polymorphism and propensity to anxiety in an Australian population-based longitudinal study of adolescent health. Psychiatr. Genet. 15: 109-115.
37. ZUBIETA, J.K., M.M. HEITZEG, Y.R. SMITH, et al. 2003. COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 299: 1240-1243.
38. KAUHANEN, J., T. HALLIKAINEN, T.P. TUOMAINEN, et al. 2000. Association between the functional polymorphism of catechol-O-methyltransferase gene and alcohol consumption among social drinkers. Alcohol. Clin. Exp. Res. 24: 135-139.
39. HALLIKAINEN, T., H. LACHMAN, T. SAITO, et al. 2000. Lack of association between the functional variant of the catechol-o-methyltransferase (COMT) gene and early-onset alcoholism associated with severe antisocial behavior. Am. J. Med. Genet. 96: 348-352.
40. TIIHONEN, J., T. HALLIKAINEN, H. LACHMAN, et al. 1999. Association between the functional variant of the catechol-o-methyltransferase (COMT) gene and type 1 alcoholism. Mol. Psychiatry 4: 286-289.
41. ENOCH, M.-A., J. WAHEED, C.R. HARRIS, et al. 2006. Sex differences in the influence of COMT Val158Met on alcoholism and smoking in Plains American Indians. Alcohol. Clin. Exp. Res. 30: 399-406.