β Amyloid angiogenic activity in vitro and in vivo

International Journal of Molecular Medicine

Volumn 19, Issue 4, 2007, Pages 581-587

  Boscolo, Elisa ^a   Folin, Marcella ^a   Nico, Beatrice ^b   Grandi, Claudio ^a   Mangieri, Domenica ^b   Longo, Vito ^b   Scienza, Renato ^c   Zampieri, Paolo ^c   Conconi, Maria Teresa ^a   Parnigotto, Pier Paolo ^a   Ribatti, Domenico ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c UNIVERSITY HOSPITAL OF PADOVA   (Italy)

Author keywords

Alzheimer's disease; Angiogenesis; Beta amyloid

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AORTA; ARTICLE; BRAIN; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; HUMAN; NEOVASCULARIZATION (PATHOLOGY); PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AORTA; BRAIN; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; PEPTIDE FRAGMENTS;

EID: 34247847748     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.19.4.581     Document Type: Article

References (24)

1. Folkman J: Angiogenesis in cancer, vascular, rheumatoid arthritis and other diseases. Nat Med 1: 27-31, 1995.
2. Vagnucci AH Jr and Li WW: Alzheimer's disease and angiogenesis. Lancet 361: 605-608, 2003.
3. Ribatti D: The crucial role of vascular permeability factor/vascular endothelial growth factor in angiogenesis: a historical review. Br J Haematol 128: 303-309, 2005. (Pubitemid 40216151)
4. Greenberg DA and Jin K: From angiogenesis to neuropathology. Nature 438: 954-959, 2005.
5. Kalaria RN, Cohen DL, Premkumar DR, Nag S, La Manna JC and Lust WD: Vascular endothelial growth factor in Alzheimer's disease and experimental cerebral ischemia. Brain Res Mol Brain Res 62: 101-105, 1998. (Pubitemid 29023185)
6. Tarkowski E, Issa R, Sjogren M, Wallin A, Blennow K, Tarkowski A and Kumar P: Increased intratechal levels of the angiogenic factor VEGF and TGF-beta in Alzheimer's disease and vascular dementia. Neurobiol Aging 23: 237-243, 2002. (Pubitemid 34137098)
7. Pogue AI and Lukiw WJ: Angiogenic signaling in Alzheimer's disease. Neuroreport 15: 1507-1510, 2004.
8. Buee L, Hof PR, Roberts DD, Delacourte A, Morrison JH and Fillit HM: Immunohistochemical identification of thrombospondin in normal human brain and Alzheimer's disease. Am J Pathol 141: 783-788, 1992.
9. Selkoe DJ: Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 81: 741-766, 2001.
10. Miyakawa T: Electron microscopy of amyloid fibrils and microvessels. Ann NY Acad Sci 826: 25-34, 1997.
11. Liu F, Lau BH, Peng Q and Shah V: Pycnogenol protects vascular endothelial cells from beta-amyloid-induced injury. Biol Pharm Bull 23: 735-737, 2000. (Pubitemid 30435080)
12. Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Osteszewski BL, Lieberburg I, Koo EH and Schenk D: Amyloid beta-peptide is produced by cultured cells during normal metabolism. Nature 359: 322-325, 1992.
13. Price JM, Chi X, Hellermann G and Sutton ET: Physiological levels of beta amyloid induce cerebral vessels dysfunction and reduce endothelial nitric oxide production. Neurol Res 23: 506-512, 2001. (Pubitemid 32642784)
14. Jackson CJ, Garbett PK, Nissen B and Schrieber L: Binding of human endothelium to Ulex europaeus I-coated Dynabeads: application to the isolation of microvascular endothelium. J Cell Sci 96: 257-262, 1990.
15. Cantara S, Ziche M and Donnini S: Opposite effects of beta amyloid on endothelial cell survival: role of fibroblast growth factor-2 (FGF-2). Pharmacol Rep 57: S138-S143, 2005.
16. Guidolin D, Vacca A, Nussdorfer GG and Ribatti D: A new image analysis method based on topological and fractal parameters to evaluate the angiostatic activity of docetaxel by using Matrigel assay in vitro. Microvasc Res 67: 117-124, 2004.
17. Ribatti D, Gualandris A, Bastaki M, Vacca A, Iurlaro M, Roncali L and Presta M: New model for the study of angiogenesis and antiangiogenesis in the chick embryo chorioallantoic membrane: the gelatin sponge/chorioallantoic membrane assay. J Vasc Res 34: 455-463, 1997.
18. Ribatti D, Urbinati C, Nico B, Rusnati M, Roncali L and Presta M: Endogenous basic fibroblast growth factor is implicated in the vascularization of the chick embryo chorioallantoic membrane. Dev Biol 170: 39-49, 1995.
19. Perlmutter LS, Barron E, Chui HC: Morphologic association between microglia and senile plaque amyloid in Alzheimer's disease. Neurosci Lett 119: 32-26, 1990.
20. Nicosia RF and Ottinetti A: Growth of microvessels in serum-free matrix culture of rat aorta. A quantitative assay of angiogenesis in vitro. Lab Invest 63: 115-122, 1990.
21. Ribatti D, Nico B, Vacca A, Roncali L, Burri PH and Djonov V: Chorioallantoic membrane capillary bed: a useful target for studying angiogenesis and anti-angiogenesis in vivo. Anat Rec 264: 317-324, 2001.
22. Cantara S, Donnini S, Morbidelli L, Giacchetti A, Schulz R, Memo M and Ziche M: Physiological levels of amyloid peptides stimulate the angiogenic response through FGF-2. FASEB J 18: 1943-1945, 2004.
23. Zand L, Ryu JK and McLarnon J: Induction of angiogenesis in the β-amyloid peptide-injected rat hippocampus. Neuroreport 16: 129-132, 2005.
24. Yoshida T, Ohno-Matsui K, Ichinose S, Sato T, Iwata N, Saido TC, Hisatomi T, Mochizuki M and Morita I: The potential role of amyloid beta in the pathogenesis of age-related macular degeneration. J Clin Invest 115: 2793-2800, 2005.